Haplogroup K2b (P331) | |
---|---|
Possible time of origin | About 3,000 years younger than K-M9 40,000-50,000 years old |
Possible place of origin | Probably East Asia [1] or Southeast Asia [2] |
Ancestor | K2 |
Descendants |
|
Defining mutations | P331, CTS2019/M1205, PF5990/L405, PF5969, [3] [2] |
Haplogroup K2b (P331), also known as MPS [3] is a human y-chromosome haplogroup that is thought to be less than 3,000 years younger than K, and less than 10,000 years younger than F, meaning it probably is around 50,000 years old, according to the age estimates of Tatiana Karafet et al. 2014. [2]
Basal paragroup K2b* has not been identified among living males but was found in Upper Paleolithic Tianyuan man from China. [4]
K2b1 (P397/P399) known previously as Haplogroup MS, and Haplogroup P (P-P295), also known as K2b2 are the only primary clades of K2b. The population geneticist Tatiana Karafet and other researchers (2014) point out that K2b1, its subclades and P* are virtually restricted geographically to South East Asia and Oceania. [2] Whereas, in a striking contrast, P1 (P-M45) and its primary subclades Q and R now make up "the most frequent haplogroup in Europe, the Americas, and Central Asia and South Asia". According to Karafet et al., the estimated dates for the branching of K, K2, K2b and P point to a "rapid diversification" within K2 "that likely occurred in Southeast Asia", with subsequent "westward expansions" of P*, P1, Q and R. [2]
According to geneticist Spencer Wells, haplogroup K originated in the Middle East or Central Asia, in the region of Iran or Pakistan. [5]
Modern populations with living members of K2b1 all subclades), P* (P-P295*; K2b2*) and P2 (K2b2b) appear to be restricted to Oceania, South East Asia and Siberia.
Basal, un-mutated P1* (K2b2a*; P-M45*), in modern times, is distributed in isolated pockets, over an relatively wide area that includes Island South East Asia.
Some Negrito populations of South-East Asia carry next to noteworthy East Asian ancestry, very high levels of K2b at the subclade level. It is carried, for instance, by more than 83% of males among the Aeta (or Agta) people of the Philippines, in the form of K2b1 (60%), P* (P-P295*, a.k.a. K2b2*) and P2 (P-B253; K2b2b).
K2b1 is found in 83% of males of Papua New Guinea, and up to 60% in the Aeta people of the Philippines. [2] It is also found among other Melanesian populations, as well as indigenous Australians, and at lower levels amongst Polynesians. [2] It is also found in the Melanesian populations of Indonesia.
Major studies of indigenous Australian Y-DNA, published in 2014 and 2015, suggest that about 29% of indigenous Australian males belong to subclades of K2b1. That is, up to 27% indigenous Australian males carry haplogroup S1a1a1 (S-P308; previously known as K2b1a1 or K-P308), [2] and one study found that approximately 2.0% – i.e. 0.9% (11 individuals) of the sample in a study in which 45% of the total was deemed to be non-indigenous – belonged to haplogroup M1 (M-M4; also known as M-M186 and known previously as haplogroup K2b1d1). All of these males carrying M1 were Torres Strait Islanders. [6] (The other Y-DNA haplogroups found were: basal K2* [K-M526], C1b2b [M347; previously Haplogroup C4], and basal C* [M130].)
Population | K2b1 (including haplogroups M & S) |
---|---|
Papua New Guinea | 82.76% |
Maori | 03.82% (1.95% of those sampled, i.e. 49% of Maori males were deemed to have non-indigenous Y-DNA) |
Fiji | 60.75% |
Solomon Islands | 71.9% |
French Polynesia | 08% |
Vanuatu | 76.5% |
New Caledonia | |
Guam | 33.3% (small sample size) |
Samoa | 08.04% |
Kiribati | 00% (small sample size) |
Tonga | 20.69% |
Micronesia FDR | 66.67% |
Marshall Islands | 63.64% |
American Samoa | |
Northern Mariana Islands | |
Palau | 61.5% (small sample size) |
Cook Islands | 03.9% |
Wallis and Futuna | 26% |
Tuvalu | 36% |
Nauru | 28.6% (small sample size) |
Norfolk Island | |
Niue | 00% (small sample size) |
Tokelau | 50% (small sample size) |
Hawaii | 20% (small sample size from FTDNA) |
Aboriginal Australians | 29% [6] |
Timor | 25% |
Aeta | 60% |
Malaysia | 02.40% ( small sample size ) |
Flores | 35% |
Sulawesi | 11.3% |
Sulawesi | 00% |
East Indonesia (Lesser Sunda Islands) | 25.9% |
Java Indonesia | 00% |
Bali Indonesia | 00.9% |
Sumatra Indonesia | 00% |
Borneo Indonesia | 05.8% |
West Papua (Papua Province, Indonesia) | 52.6% |
West Papua (Papua Province, Indonesia) | 82.6% |
Sumba Indonesia | 25.2% |
Chukkese people Micronesia | 76.5% |
Pohnpeian people Micronesia | 70% (small sample size) |
Apart from the basal paragroup P* (K2b2), it has only one subclade: P1 (M45), also known as K2b2a – which is also the parent of the major haplogroups Q (K2b2a1) and R (K2b2a2). [2]
P (K2b2) descendant haplogroups Q (K2b2a1) and R (K2b2a2) is widely distributed among males of Native American, Central Asian, South Asian and Siberian ancestry.
P-P295* (sometimes known as "pre-P", before P-M45 was redesignated P1) is found among 28% of males among the Aeta, as well as in Timor at 10.8%, and one case may have been found in Papua New Guinea (Kaysar et al. 2006) although this has not been verified. [2]
Population | Rate of P* (%) | Notes |
---|---|---|
Papua New Guinea | 0.69 | assumed from Kayser et al. 2006, i.e. one P* found |
New Zealand | 0 | |
Fiji | 0 | |
Solomon Islands | 0 | |
French Polynesia | 0 | |
Vanuatu | 0 | |
New Caledonia | ||
Guam | 0 | |
Samoa | 0 | |
Kiribati | ||
Tonga | 0 | |
Federated States of Micronesia | 0 | |
Marshall Islands | 0 | |
American Samoa | ||
Northern Mariana Islands | ||
Palau | ||
Cook Islands | 0 | |
Wallis and Futuna | 0 | |
Tuvalu | 0 | |
Nauru | ||
Norfolk Island | ||
Niue | 0 | small sample size |
Tokelau | 0 | small sample size |
Hawaii | 0 | small sample size from FTDNA |
Australia | 0 | |
Timor | 10.8 | |
Aeta | 28 | |
Filipino Austronesian | 0 | |
Malay | 0 | |
Flores | 0 | |
Sulawesi | 0.6 | |
East Indonesia | 0 | |
Java Indonesia | 0 | |
Bali Indonesia | 0 | |
Sumatra Indonesia | 0 | |
Borneo Indonesia | 0 | |
West Papua Province | 0 | |
Papua Province | 0 | |
Sumba Indonesia | 3.2 |
P1 (M45/PF5962), also known as K2b2a, is hundreds of times more common than P* (K2b2; PxM45), as it includes haplogroups Q and R, is estimated as being 14,300 years younger than K2b. [2]
Many ethnic groups with high frequencies of P1 are located in Central Asia and Siberia: 35.4% among Tuvans, 28.3% among Altaian Kizhi, [7] and 35% among Nivkh males.
Modern South Asian populations also feature P1 at low to moderate frequencies. [8] In South Asia it is most frequent among the Muslims of Manipur (33%), but this may be due to a very small sample size (nine individuals). Cases of P1 (M45) reported in South Asia may be unresolved cases or R2 or Q. [8]
Population group (with ethnolinguistic affiliation) | Paper | N | Percentage | SNPs Tested | |
---|---|---|---|---|---|
Tuvinian (Turkic) | Darenko 2005 | 113 | 35.40 | P-M45 | |
Nivkh (isolate) | Lell 2001 | 17 | 35 | P-M45 | |
Altai-Kizhi (Altaians) (Turkic) | Darenko 2005 | 92 | 28.3 | P-M45 | |
Todjin (Turkic) | Darenko 2005 | 36 | 22.2 | P-M45 | |
Chukchi (Chukotkan) | Lell 2001 | 24 | 20.8 | P-M45 | |
Koryak (Chukotkan) | Lell 2001 | 27 | 18.5 | P-M45 | |
Yupik (Eskimo-Aleut) | Lell 2001 | 33 | 18.2 | P-M45 | |
Uighur (Turkic) | Xue 2006 | 70 | 17.1 | P-M45 | |
Kalmyk (Mongolic) | Darenko 2005 | 68 | 11.8 | P-M45 | |
Turkmen (Turkic) | Wells 2001 | 30 | 10 | P-M45 | |
Soyot (Turkic) | Darenko 2005 | 34 | 8.8 | P-M45 | |
Uriankhai (Mongolic) | Katoh 2004 | 60 | 8.3 | P-M45 | |
Khakas (Turkic) | Darenko 2005 | 53 | 7.6 | P-M45 | |
Kazakh (Turkic) | Wells 2001 | 54 | 5.6 | P-M45 | |
Uzbek (Turkic) | Wells 2001 | 366 | 5.5 | P-M45 | |
Khasi-Khmuic (Austro-Asiatic) | Reddy 2009 | 353 | 5.40 | P-M45(xM173) § | |
Mundari (Austro-Asiatic) | Reddy 2009 | 64 | 10.90 | P-M45(xM173) § | |
Nicobarese (Mon-Khmer) | Reddy 2009 | 11 | 0.00 | P-M45(xM173) § | |
Southeast Asia ( Austro-Asiatic ) | Reddy 2009 | 257 | 1.60 | P-M45(xM173) § | |
Garo (Tibeto-Burman) | Reddy 2009 | 71 | 1.40 | P-M45(xM173) § | |
India ( Tibeto-Burman ) | Reddy 2009 | 226 | 3.10 | P-M45(xM173) § | |
East Asia (Tibeto-Burman) | Reddy 2009 | 214 | 0.00 | P-M45(xM173) § | |
Eastern India ( Indo-European ) | Reddy 2009 | 54 | 18.50 | P-M45(xM173) § | |
Iran (Southern Talysh ) | Nasidze 2009 | 50 | 4.00 | P-M45(xM124,xM173) | |
Azerbaijan (Northern Talysh ) | Nasidze 2009 | 40 | 5.00 | P-M45(xM124,xM173) | |
Mazandarani (Iranian) | Nasidze 2009 | 50 | 4.00 | P-M45(xM124,xM173) | |
Gilaki (Iranian) | Nasidze 2009 | 50 | 0.00 | P-M45(xM124,xM173) | |
Tehran (Iranian) | Nasidze 2004 | 80 | 4.00 | P-M45(xM124,xM173) | |
Isfahan (Iranian) | Nasidze 2004 | 50 | 6.00 | P-M45(xM124,xM173) | |
Bakhtiari (Iranian) | Nasidze 2008 | 53 | 2.00 | P-M45(xM124,xM173) | |
Iranian Arabs (Arabic) | Nasidze 2008 | 47 | 2.00 | P-M45(xM124,xM173) | |
North Iran (Iranian) | Regueiro 2006 | 33 | 9.00 | P-M45(xM124,xM173) | |
South Iran (Iranian) | Regueiro 2006 | 117 | 3.00 | P-M45(xM124,xM173) | |
South Caucacus ( Georgian ) | Nasidze and Stoneking 2001 | 77 | 3.00 | P-M45(xM124,xM173) | |
South Caucacus ( Armenian ) | Nasidze and Stoneking 2001 | 100 | 2.00 | P-M45(xM124,xM173) | |
Hvar ( Croatian ) | Barać et al. 2003 | 14 | |||
Korčula ( Croatian ) | Barać et al. 2003 | 6 |
§ These may include members of haplogroup R2.
Population group | N | P (xQ,xR) | Q | R | Paper | |||
---|---|---|---|---|---|---|---|---|
Count | % | Count | % | Count | % | |||
Gope | 16 | 1 | 6.4 | Sahoo 2006 | ||||
Oriya Brahmin | 24 | 1 | 4.2 | Sahoo 2006 | ||||
Mahishya | 17 | 3 | 17.6 | Sahoo 2006 | ||||
Bhumij | 15 | 2 | 13.3 | Sahoo 2006 | ||||
Saora | 13 | 3 | 23.1 | Sahoo 2006 | ||||
Nepali | 7 | 2 | 28.6 | Sahoo 2006 | ||||
Muslims of Manipur | 9 | 3 | 33.3 | Sahoo 2006 | ||||
Himachal Pradesh Rajput | 15 | 1 | 6.7 | Sahoo 2006 | ||||
Lambadi | 18 | 4 | 22.2 | Sahoo 2006 | ||||
Gujarati Patel | 9 | 2 | 22.2 | Sahoo 2006 | ||||
Katkari | 19 | 1 | 5.3 | Sahoo 2006 | ||||
Madia Gond | 14 | 1 | 7.1 | Sahoo 2006 | ||||
Kamma Chowdary | 15 | 0 | 0 | 1 | 6.7 | 12 | 80 | Sahoo 2006 |
Assuming B70 ky for the TMRCA of M168 chromosomes,10 we estimate the interval of time between the diversification of K-M9 and that of K-P331 to be <3 ky. This rapid diversification has also been assessed using whole Y-chromosome sequence data.22 In addition, we estimate the total time between the common ancestor of K-M9 and that of P-P295 to be <5 ky, and the time between the common ancestor P-P295 and that of P-P27 to be 12.3 ky (95% CI: 6.6–20 ky). [2]
A haplotype is a group of alleles in an organism that are inherited together from a single parent, and a haplogroup is a group of similar haplotypes that share a common ancestor with a single-nucleotide polymorphism mutation. More specifically, a haplotype is a combination of alleles at different chromosomal regions that are closely linked and that tend to be inherited together. As a haplogroup consists of similar haplotypes, it is usually possible to predict a haplogroup from haplotypes. Haplogroups pertain to a single line of descent. As such, membership of a haplogroup, by any individual, relies on a relatively small proportion of the genetic material possessed by that individual.
Haplogroup J-M304, also known as J, is a human Y-chromosome DNA haplogroup. It is believed to have evolved in Western Asia. The clade spread from there during the Neolithic, primarily into North Africa, the Horn of Africa, the Socotra Archipelago, the Caucasus, Europe, Anatolia, Central Asia, South Asia, and Southeast Asia.
Haplogroup D1 or D-M174 is a subclade of haplogroup D-CTS3946. This male haplogroup is found primarily in East Asia, Magar-ethnic Nepal and the Andaman Islands. It is also found regularly with lower frequency in Central Asia, Siberia and Mainland Southeast Asia, and, more rarely, in Europe and the Middle East.
Haplogroup K or K-M9 is a genetic lineage within human Y-chromosome DNA haplogroup. A sublineage of haplogroup IJK, K-M9, and its descendant clades represent a geographically widespread and diverse haplogroup. The lineages have long been found among males on every continent except Antarctica.
Haplogroup M, also known as M-P256 and Haplogroup K2b1b is a Y-chromosome DNA haplogroup. M-P256 is a descendant haplogroup of Haplogroup K2b1, and is believed to have first appeared between 32,000 and 47,000 years ago.
Haplogroup P also known as P-F5850 or K2b2 is a Y-chromosome DNA haplogroup in human genetics. P-F5850 is a branch of K2b, which is a branch of Haplogroup K2 (K-M526).
Haplogroup Q or Q-M242 is a Y-chromosome DNA haplogroup. It has one primary subclade, Haplogroup Q1 (L232/S432), which includes numerous subclades that have been sampled and identified in males among modern populations.
In human genetics, a human Y-chromosome DNA haplogroup is a haplogroup defined by mutations in the non-recombining portions of DNA from the male-specific Y chromosome. Many people within a haplogroup share similar numbers of short tandem repeats (STRs) and types of mutations called single-nucleotide polymorphisms (SNPs).
Haplogroup R, or R-M207, is a Y-chromosome DNA haplogroup. It is both numerous and widespread amongst modern populations.
Haplogroup NO1, also known as NO-M214, is a human Y-chromosome DNA haplogroup. NO1 is the sole confirmed subclade of Haplogroup K- M2313, which is the sole subclade of Haplogroup K2a (K-M2308). NO is the dominant Y-DNA haplogroup in most parts of eastern and northern Eurasia, including East Asia, Siberia and northern Fennoscandia.
Haplogroup DE is a human Y-chromosome DNA haplogroup. It is defined by the single nucleotide polymorphism (SNP) mutations, or UEPs, M1(YAP), M145(P205), M203, P144, P153, P165, P167, P183. DE is unique because it is distributed in several geographically distinct clusters. An immediate subclade, haplogroup D, is mainly found in East Asia, parts of Central Asia, and the Andaman Islands, but also sporadically in West Africa and West Asia. The other immediate subclade, haplogroup E, is common in Africa, and to a lesser extent the Middle East and southern Europe.
Haplogroup CT is a human Y chromosome haplogroup. CT has two basal branches, CF and DE. DE is divided into a predominantly Asia-distributed haplogroup D-CTS3946 and a predominantly Africa-distributed haplogroup E-M96, while CF is divided into an East Asian, Native American, and Oceanian haplogroup C-M130 and haplogroup F-M89, which dominates most non-African populations.
Haplogroup K2, also known as K-M526 and formerly known as K(xLT) and MNOPS, is a human Y-DNA haplogroup.
Haplogroup S-M230, also known as S1a1b, is a Y-chromosome DNA haplogroup. It is by far the most numerically significant subclade of Haplogroup S1a.
Haplogroup IJK is a human Y-chromosome DNA haplogroup. IJK is a primary branch of the macrohaplogroup HIJK. Its direct descendants are haplogroup IJ and haplogroup K.
Haplogroup R1b (R-M343), previously known as Hg1 and Eu18, is a human Y-chromosome haplogroup.
In human population genetics, Y-Chromosome haplogroups define the major lineages of direct paternal (male) lines back to a shared common ancestor in Africa. Men in the same haplogroup share a set of differences, or markers, on their Y-Chromosome, which distinguish them from men in other haplogroups. These UEPs, or markers used to define haplogroups, are SNP mutations. Y-Chromosome Haplogroups all form "family trees" or "phylogenies", with both branches or sub-clades diverging from a common haplogroup ancestor, and also with all haplogroups themselves linked into one family tree which traces back ultimately to the most recent shared male line ancestor of all men alive today, called in popular science Y Chromosome Adam.
Haplogroup K2b1, known sometimes as haplogroup MS, is a human Y-DNA haplogroup, defined by SNPs P397 and P399. It has a complex, diverse and not-yet fully understood internal structure; its downstream descendants include the major haplogroups Haplogroup M (P256) and Haplogroup S (M230).
Haplogroup P1, also known as P-M45 and K2b2a, is a Y-chromosome DNA haplogroup in human genetics. Defined by the SNPs M45 and PF5962, P1 is a primary branch (subclade) of P.
Haplogroup K2a is a human Y-chromosome DNA haplogroup. K2a is a primary subclade of haplogroup K2 (M526), which in turn is a primary descendant of haplogroup K (M9). Its sole primary descendant is haplogroup K-M2313.
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