Haplogroup K-M9

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Haplogroup K
Haplogroup K of Y-DNA.png
Possible time of origin55,000-50,000
Possible place of origin West Asia, Central Asia, [1] [2] [3] or Southeast Asia [4] [5]
Ancestor IJK
Descendants K2, [6] LT
Defining mutationsM9, P128/PF5504, P131/PF5493, P132/PF5480

Haplogroup K or K-M9 is a genetic lineage within human Y-chromosome DNA haplogroup. A sublineage of haplogroup IJK, K-M9, and its descendant clades represent a geographically widespread and diverse haplogroup. The lineages have long been found among males on every continent except Antarctica.

Contents

The direct descendants of Haplogroup K1 (L298 = P326, also known as LT) and K-M9 are Haplogroup K2 (formerly KxLT; K-M526). [6] [7]

Origins and distribution

Y-DNA haplogroup K-M9 is an old lineage that arose approximately 47,000-50,000 years ago. [8] Geneticist Spencer Wells had argued that because haplogroup K has a geographically wide distribution, the lineage probably originated near the central part of this range in the Middle East or Central Asia, possibly in Iran or Pakistan. [1] [2] [3]

Basal K* is exceptionally rare and under-researched; while it has been reported at very low frequencies on many continents it is not always clear if the examples concerned have been screened for subclades. [6] [9] Confirmed examples of K-M9* now appear to be most common amongst some populations in Island South East Asia and Melanesia. [10] [11] [12]

Primary descendants of haplogroup LT are L (M20), also known as K1a, and T (M184), also known as K1b. [6] [7]

The descendants of haplogroup K2 include:

Structure

Haplogroup K-M9 tree [6] [16] [17] [18] [19] [20] [21] [22] [23] [24] [25] [26] [27] [28] [29] [30] [31] [32] [33] [34]

LT (L298; a.k.a. K1) has never been found in basal form (LT*). Subclades are widely distributed at low concentrations. Haplogroup L is found at its highest frequency in India, Pakistan and among the Baloch of Afghanistan. T is most common among: Fulanis, Toubou, Tuareg, Somaliland, Egyptians, some Middle East, [35] the Aegean Islands and among Kurru, Bauris and Lodha in India.

K2

K2* (M526) has been found in an estimated 27% of indigenous Australians (based on large scale surveys in which 56% of the samples were assumed to be non-indigenous.). [36] According to Mark Lipson et al.(2014), from MIT – Massachusetts Institute of Technology, United States Of America, from his jurnal: "New  statistical  genetic methods for elucidating the history and evolution of human populations”, K2* (M526) has also been found in Toba-Batak and Mandar in an estimated 14%. Only Toba Batak and Mandar have K2* (M526) from indigenous Sunda land [37]

K2a  (K-M2308) [13]

K2a* - found only in the remains of Ust'-Ishim man, dating from approximately 45,000 BP and found in
Omsk Oblast, Russia. [13] (These remains were initially classified, erroneously, as K2*.)

K-M2313*

K-M2313* [13] – so far found only in one Telugu male and one ethnic Malay, and ancient Oase-1.

NO (M214; a.k.a. K2a2) – The two primary branches of NO include the major
haplogroups:
• N, which is found mainly in populations across Northern Eurasia (and at lower frequencies in regions including East Asia, Central Asia,
Southeast Asia, Anatolia, and Southeast Europe) and;
• O, which is now numerically dominant among males from East Asia, Southeast Asia, and the Pacific Islands.

K2b  (P331)
K2b1

S (B254) which is numerically dominant in the highlands of Papua New Guinea; [38] subclades of S1, such as S1a3 (P315) and S1a1a1 (P308), [39] have also been reported at levels of up to 27% among indigenous Australians, while [36] S1a (P405; previously K2b1a) has also been found at significant levels in other parts of Oceania. S2 (P336; previously K2b1b) has been found on Alor, Timor and Borneo and; S3 (P378; previously K2b1c) found among Aeta people of the Philippines.

M (P256, Page93/S322) a.k.a. K2b1b (previously K2b1d) is the most common haplogroup in both West Papua and Papua New Guinea; also found in Australia, [36] and neighbouring parts of Melanesia and Polynesia.

P  (K2b2)
P* (K2b2*) 28% of  Aeta  (Philippines), 10% in  Timor
P1*(M45/PF5962)

P1* 22.2–35.4% in Tuvans, Kizhi, Todjins and also in Andamanese_peoples of India

Q (M242) Native Americans and Siberia/Central Asia (Kets, Selkups, Altai, Tuvans, Xirong, Mongolian Altai Kurgans)

R* found only in remains from 24,000 years BP at Mal'ta' in Siberia

R2 found in South Asia and parts of Central Asia, Caucasus and the Middle East

R1a found in Eastern Europe, South Asia, Central Asia, and Scandinavia. Ancient samples include 10 out of 11 samples from Xiaohe Tomb complex, Andronovo, Pazyryk, Mongolian Altai Kurgans (R1a/Z93 mixed with Q1a2a1/L54), The Tagar Culture, Karasuk culture, Tashtyk culture, some Corded ware folk

R1b West Europe, Chadic Languages, Banjara tribes of India, Hazaras of Pakistan, Armenian Highlands (Found in several Bell Beakers from Germany and in late antique Basques of whom it is still common in as well as 13.3% (4):one P probably R1b2 (V88): of Guanches from the Canary Islands, (reports of King Tut belonging to R1b, by iGENEA belonging to R1b have not been verified.)

K2c (P261). Minor lineage of Bali.

K2d (P402). Minor lineage of Java

K2e (M147). Highly rare lineage; two cases in South Asia. [40]

References

  1. 1 2 Wells, Spencer (20 November 2006). Deep Ancestry: The Landmark DNA Quest to Decipher Our Distant Past. National Geographic. p. 79. ISBN   978-1-4262-0211-7. Archived from the original on 11 December 2023. Given the widespread distribution of K, it probably arose somewhere in the Middle East or Central Asia, perhaps in the region of Iran or Pakistan.
  2. 1 2 Wells, Spencer (28 March 2017). The Journey of Man: A Genetic Odyssey. Princeton University Press. p. 111. ISBN   978-0-691-17601-7.
  3. 1 2 Chanda, Nayan (1 October 2008). Bound Together: How Traders, Preachers, Adventurers, and Warriors Shaped Globalization. Yale University Press. p. 15. ISBN   978-0-300-13490-2.
  4. ↑ Karafet, Tatiana M; Mendez, Fernando L; Sudoyo, Herawati; Lansing, J Stephen; Hammer, Michael F (March 2015). "Improved phylogenetic resolution and rapid diversification of Y-chromosome haplogroup K-M526 in Southeast Asia". European Journal of Human Genetics. 23 (3): 369–373. doi:10.1038/ejhg.2014.106. PMC   4326703 . PMID   24896152.
  5. ↑ Hallast, Pille; Agdzhoyan, Anastasia; Balanovsky, Oleg; Xue, Yali; Tyler-Smith, Chris (2021). "A Southeast Asian origin for present-day non-African human y chromosomes". Human Genetics. 140 (2): 299–307. doi:10.1007/s00439-020-02204-9. PMC   7864842 . PMID   32666166.
  6. 1 2 3 4 5 "Y-DNA Haplogroup Tree 2019-2020". International Society of Genetic Genealogy. 11 July 2020. Archived from the original on 31 January 2024. Retrieved 8 May 2020.
  7. 1 2 Chiaroni, J.; Underhill, P. A.; Cavalli-Sforza, L. L. (December 2009). "Y chromosome diversity, human expansion, drift, and cultural evolution". Proc. Natl. Acad. Sci. U.S.A. 106 (48): 20174–9. Bibcode:2009PNAS..10620174C. doi: 10.1073/pnas.0910803106 . JSTOR   25593348. PMC   2787129 . PMID   19920170.
  8. ↑ Karafet TM, Mendez FL, Meilerman MB, Underhill PA, Zegura SL, Hammer MF (May 2008). "New binary polymorphisms reshape and increase resolution of the human Y chromosomal haplogroup tree". Genome Res. 18 (5): 830–8. doi:10.1101/gr.7172008. PMC   2336805 . PMID   18385274.
  9. ↑ Daine J., Rowold; et al. (2016). "On the Bantu expansion" . Gene. 593 (1): 48–57. doi:10.1016/j.gene.2016.07.044. PMID   27451076 . Retrieved 13 October 2016– via Elsevier Science Direct.
  10. ↑ Delfin, Frederick; et al. (29 September 2010). "The Y-chromosome landscape of the Philippines: extensive heterogeneity and varying genetic affinities of Negrito and non-Negrito groups". European Journal of Human Genetics. 19 (2). Nature Publishing Group: 224–230. doi: 10.1038/ejhg.2010.162 . eISSN   1476-5438. ISSN   1018-4813. PMC   3025791 . PMID   20877414.
  11. ↑ Karafet, Tatiana M; Lansing, J S; Redd, Alan J; Reznikova, Svetlana; Watkins, Joseph C; Surata, S P K; Arthawiguna, W A; Mayer, Laura; Bamshad, Michael; Jorde, Lynn B; Hammer, Michael F (February 2005). "Balinese Y-chromosome perspective on the peopling of Indonesia: genetic contributions from pre-neolithic hunter-gatherers, Austronesian farmers, and Indian traders" . Human Biology. 77 (1): 93–114. doi:10.1353/hub.2005.0030. eISSN   1534-6617. hdl: 1808/13586 . ISSN   0018-7143. PMID   16114819. S2CID   7953854. Archived from the original on 31 January 2024 – via Project MUSE.
  12. ↑ Cox, Murray P; Lahr, Marta Mirazón (25 December 2005). "Y-chromosome diversity is inversely associated with language affiliation in paired Austronesian- and Papuan-speaking communities from Solomon Islands" . American Journal of Human Biology. 18 (1): 35–50. doi:10.1002/ajhb.20459. PMID   16378340. S2CID   4824401 – via Wiley Online Library.
  13. 1 2 3 4 Poznik, G. David; et al. (25 April 2016). "Punctuated bursts in human male demography inferred from 1,244 worldwide Y-chromosome sequences". Nature Genetics. 48 (6): 593–599. doi:10.1038/ng.3559. eISSN   1546-1718. hdl:11858/00-001M-0000-002A-F024-C. ISSN   1061-4036. PMC   4884158 . PMID   27111036.
  14. ↑ Rootsi, Siiri; et al. (1 February 2007). "A counter-clockwise northern route of the Y-chromosome haplogroup N from Southeast Asia towards Europe". European Journal of Human Genetics. 15 (2): 204–211. doi: 10.1038/sj.ejhg.5201748 . eISSN   1476-5438. ISSN   1018-4813. PMID   17149388.
  15. ↑ Karafet TM, Mendez FL, Meilerman MB, Underhill PA, Zegura SL, Hammer MF (May 2008). "New binary polymorphisms reshape and increase resolution of the human Y chromosomal haplogroup tree". Genome Research. 18 (5): 830–8. doi:10.1101/gr.7172008. PMC   2336805 . PMID   18385274.
  16. ↑ Karafet TM, Mendez FL, Sudoyo H, Lansing JS, Hammer MF (June 2014). "Improved phylogenetic resolution and rapid diversification of Y-chromosome haplogroup K-M526 in Southeast Asia". European Journal of Human Genetics. 23 (3): 369–373. doi:10.1038/ejhg.2014.106. PMC   4326703 . PMID   24896152.
  17. ↑ Raghavan M, Skoglund P, Graf KE, et al. (January 2014). "Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans". Nature. 505 (7481): 87–91. Bibcode:2014Natur.505...87R. doi:10.1038/nature12736. PMC   4105016 . PMID   24256729.
  18. ↑ Rasmussen M, Anzick SL, Waters MR, et al. (February 2014). "The genome of a Late Pleistocene human from a Clovis burial site in western Montana". Nature. 506 (7487): 225–9. Bibcode:2014Natur.506..225R. doi:10.1038/nature13025. PMC   4878442 . PMID   24522598.
  19. ↑ Hollard C, Keyser C, Giscard PH, et al. (September 2014). "Strong genetic admixture in the Altai at the Middle Bronze Age revealed by uniparental and ancestry informative markers". Forensic Science International: Genetics. 12: 199–207. doi:10.1016/j.fsigen.2014.05.012. PMID   25016250.
  20. ↑ Fregel R, Gomes V, Gusmão L, et al. (2009). "Demographic history of Canary Islands male gene-pool: replacement of native lineages by European". BMC Evolutionary Biology. 9 (1): 181. Bibcode:2009BMCEE...9..181F. doi: 10.1186/1471-2148-9-181 . PMC   2728732 . PMID   19650893.
  21. ↑ Grugni V, Battaglia V, Hooshiar Kashani B, et al. (2012). "Ancient migratory events in the Middle East: new clues from the Y-chromosome variation of modern Iranians". PLOS ONE. 7 (7): e41252. Bibcode:2012PLoSO...741252G. doi: 10.1371/journal.pone.0041252 . PMC   3399854 . PMID   22815981.
  22. ↑ Haber M, Platt DE, Ashrafian Bonab M, et al. (2012). "Afghanistan's ethnic groups share a Y-chromosomal heritage structured by historical events". PLOS ONE. 7 (3): e34288. Bibcode:2012PLoSO...734288H. doi: 10.1371/journal.pone.0034288 . PMC   3314501 . PMID   22470552.
  23. ↑ Bekada A, Fregel R, Cabrera VM, et al. (2013). "Introducing the Algerian mitochondrial DNA and Y-chromosome profiles into the North African landscape". PLOS ONE. 8 (2): e56775. Bibcode:2013PLoSO...856775B. doi: 10.1371/journal.pone.0056775 . PMC   3576335 . PMID   23431392.
  24. ↑ Rosser ZH, Zerjal T, Hurles ME, et al. (December 2000). "Y-chromosomal diversity in Europe is clinal and influenced primarily by geography, rather than by language". American Journal of Human Genetics. 67 (6): 1526–43. doi:10.1086/316890. PMC   1287948 . PMID   11078479.
  25. ↑ Pichler I, Mueller JC, Stefanov SA, et al. (August 2006). "Genetic structure in contemporary south Tyrolean isolated populations revealed by analysis of Y-chromosome, mtDNA, and Alu polymorphisms". Human Biology. 78 (4): 441–64. doi:10.1353/hub.2006.0057. PMID   17278620. S2CID   20205296.
  26. ↑ Robino C, Varacalli S, Gino S, et al. (October 2004). "Y-chromosomal STR haplotypes in a population sample from continental Greece, and the islands of Crete and Chios". Forensic Science International. 145 (1): 61–4. doi:10.1016/j.forsciint.2004.02.026. PMID   15374596.
  27. ↑ Trivedi, R.; Sahoo, Sanghamitra; Singh, Anamika; Bindu, G. Hima; Banerjee, Jheelam; Tandon, Manuj; Gaikwad, Sonali; Rajkumar, Revathi; Sitalaximi, T; Ashma, Richa; Chainy, G. B. N.; Kashyap, V. K. (2007). "High Resolution Phylogeographic Map of Y-Chromosomes Reveal the Genetic Signatures of Pleistocene Origin of Indian Populations" (PDF). Anthropology Today.
  28. ↑ Hirbo, Jibril Boru (2011). Complex Genetic History of East African Human Populations (PhD Thesis). hdl:1903/11443.[ page needed ]
  29. ↑ Sanchez, J.J. (2004). "Y chromosome SNP haplogroups in Danes, Greenlanders and Somalis". International Congress Series. 1261: 347–349. doi:10.1016/S0531-5131(03)01635-2.
  30. ↑ Cruciani F, Trombetta B, Sellitto D, et al. (July 2010). "Human Y chromosome haplogroup R-V88: a paternal genetic record of early mid Holocene trans-Saharan connections and the spread of Chadic languages". European Journal of Human Genetics. 18 (7): 800–7. doi:10.1038/ejhg.2009.231. PMC   2987365 . PMID   20051990.
  31. ↑ yhrd.org[ full citation needed ]
  32. ↑ Zhong, Hua; Shi, Hong; Qi, Xue-Bin; Duan, Zi-Yuan; Tan, Ping-Ping; Jin, Li; Su, Bing; Ma, Runlin Z. (2010). "Extended Y Chromosome Investigation Suggests Postglacial Migrations of Modern Humans into East Asia via the Northern Route". Molecular Biology and Evolution. 28 (1): 717–27. doi: 10.1093/molbev/msq247 . PMID   20837606.
  33. ↑ "PhyloTree Y - Minimal Y tree". www.phylotree.org.
  34. ↑ Magoon, Gregory R; Banks, Raymond H; Rottensteiner, Christian; Schrack, Bonnie E; Tilroe, Vincent O; Robb, Terry; Grierson, Andrew J (2013). "Generation of high-resolution a priori Y-chromosome phylogenies using 'next-generation' sequencing data". bioRxiv   10.1101/000802 .
  35. ↑ "FamilyTreeDNA - Arab T Haplogroup".
  36. 1 2 3 Nagle, N.; Ballantyne, K. N.; Van Oven, M.; Tyler-Smith, C.; Xue, Y.; Taylor, D.; Wilcox, S.; Wilcox, L.; Turkalov, R.; Van Oorschot, R. A.; McAllister, P.; Williams, L.; Kayser, M.; Mitchell, R. J.; Genographic, Consortium (2016). "Antiquity and diversity of aboriginal Australian Y-chromosomes". American Journal of Physical Anthropology. 159 (3): 367–381. doi:10.1002/ajpa.22886. PMID   26515539.
  37. ↑ Lipson, Mark; Loh, Po-Ru; Patterson, Nick; Moorjani, Priya; Ko, Ying-Chin; Stoneking, Mark; Berger, Bonnie; Reich, David (2014). "Reconstructing Austronesian population history in Island Southeast Asia". Nature Communications. 5: 4689. Bibcode:2014NatCo...5.4689L. doi:10.1038/ncomms5689. hdl: 11858/00-001M-0000-0024-1F46-B . PMC   4143916 . PMID   25137359.
  38. ↑ "ISOGG 2018 Y-DNA Haplogroup S".
  39. ↑ As of 2017, S1a1a1 (P308) – formerly K2b1a1 – included an unnamed subclade, identified by the SNP P60 (and previously by P304, which has been removed by ISOGG as unreliable). S1a1a1 and any sublades have only been found among indigenous Australians.
  40. ↑ International Society of Genetic Genealogy, 2020, Y-DNA Haplogroup Tree 2019-2020 (8 May 2020).
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