Haplogroup L6

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Haplogroup L6
Possible time of origin81,500-129,800 YBP [1]
Possible place of origin East Africa
AncestorL3'4'6
Descendants L6a, L6b
Defining mutations146, 152, 185C, 709, 770, 961, 1461, 4964, 5267, 6002, 6284, 9332, 10978, 11116, 11743, 12771, 13710, 14791, 14959, 5244, 15289, 15499, 16048, 16224 [2]

In human mitochondrial genetics, Haplogroup L6 is a human mitochondrial DNA (mtDNA) haplogroup. It is a small African haplogroup. [3]

Contents

Distribution

Projected spatial frequency distribution for haplogroup L6. Frequency maps based on HVS-I data for haplogroups L6.png
Projected spatial frequency distribution for haplogroup L6.
Schematic tree of mtDNA haplogroup L6 (and L4). Ages (in ka) indicated are maximum likelihood estimates obtained for the whole-mtDNA genome. Schematic tree of mtDNA haplogroups L4 and L6.png
Schematic tree of mtDNA haplogroup L6 (and L4). Ages (in ka) indicated are maximum likelihood estimates obtained for the whole-mtDNA genome.

This haplogroup has been found most often in Yemen and Ethiopia. [4]

Subclades

Tree

This phylogenetic tree of haplogroup M subclades is based on the paper by Mannis van Oven and Manfred Kayser Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation [2] and subsequent published research.

See also

Related Research Articles

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References

  1. ↑ Soares, P; Ermini, L; Thomson, N; Mormina, M; Rito, T; Röhl, A; Salas, A; Oppenheimer, S; et al. (2009). "Correcting for Purifying Selection: An Improved Human Mitochondrial Molecular Clock". American Journal of Human Genetics. 84 (6): 740–59. doi:10.1016/j.ajhg.2009.05.001. PMC   2694979 . PMID   19500773.
  2. 1 2 van Oven, Mannis; Manfred Kayser (13 Oct 2008). "Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation". Human Mutation. 30 (2): E386–E394. doi: 10.1002/humu.20921 . PMID   18853457. S2CID   27566749.
  3. ↑ Haplogroups L6.
  4. ↑ Abu-Amero, Khaled K; Ana M González (1 Mar 2007). "Eurasian and African mitochondrial DNA influences in the Saudi Arabian population". BMC Evolutionary Biology. 7: 752–770. doi: 10.1186/1471-2148-7-32 . PMC   1810519 . PMID   17331239.

Phylogenetic tree of human mitochondrial DNA (mtDNA) haplogroups

  Mitochondrial Eve (L)  
L0 L1–6 
L1 L2   L3    L4 L5 L6
M N  
CZ D E G Q   O A S R   I W X Y
C Z B F R0   pre-JT   P   U
HV JT K
H V J T
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