Indole-3-acetaldehyde oxidase

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indole-3-acetaldehyde oxidase
Identifiers
EC no. 1.2.3.7
CAS no. 66082-22-2
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
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PMC articles
PubMed articles
NCBI proteins

In enzymology, indole-3-acetaldehyde oxidase (EC 1.2.3.7) is an enzyme that catalyzes the chemical reaction

+ H2O
 
 
O2
H2O2
Indole-3-acetaldehyde oxidase
O2
H2O2
 

The three substrates of this enzyme are indole-3-acetaldehyde, water, and oxygen. Its products are indole-3-aceticacid and hydrogen peroxide. [1] [2] [3] [4] [5]

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with oxygen as acceptor. The systematic name of this enzyme class is (indol-3-yl)acetaldehyde:oxygen oxidoreductase. Other names in common use include indoleacetaldehyde oxidase, IAAld oxidase, AO1, and indole-3-acetaldehyde:oxygen oxidoreductase. This enzyme participates in tryptophan metabolism. It has 3 cofactors: flavin adenine dinucleotide, heme, and molybdenum. [6] [7] [8]

References

  1. Enzyme 1.2.3.7 at KEGG Pathway Database.
  2. Bower PJ, Brown HM, Purves WK (1978). "Cucumber seedling indoleacetaldehyde oxidase". Plant Physiol. 61 (1): 107–110. doi:10.1104/pp.61.1.107. PMC   1091807 . PMID   16660220.
  3. Miyata S, Suzuki Y, Kamisaka S, Masuda Y (1981). "Indole-3-acetaldehyde oxidase of pea-seedlings". Physiol. Plant. 51 (4): 402–406. Bibcode:1981PPlan..51..402M. doi:10.1111/j.1399-3054.1981.tb05577.x.
  4. Rajagopal R (1971). "Metabolism of indole-3-acetaldehyde. III. Some characteristics of the aldehyde oxidase of Avena coleoptiles". Physiol. Plant. 24 (2): 272–281. Bibcode:1971PPlan..24..272R. doi:10.1111/j.1399-3054.1971.tb03491.x.
  5. Koshiba T, Matsuyama H (1993). "An in Vitro System of Indole-3-Acetic Acid Formation from Tryptophan in Maize (Zea mays) Coleoptile Extracts". Plant Physiol. 102 (4): 1319–1324. doi:10.1104/pp.102.4.1319. PMC   158922 . PMID   12231908.
  6. Marion-Poll A, Caboche M, Kamiya Y, Koshiba T (1998). "Molecular cloning and characterization of aldehyde oxidases in Arabidopsis thaliana". Plant Cell Physiol. 39 (4): 433–42. doi: 10.1093/oxfordjournals.pcp.a029387 . PMID   9615466.
  7. T; Akaba, S; Oritani, T; Delarue, M; Bellini, C; Caboche, M; Koshiba, T (1998). "Higher activity of an aldehyde oxidase in the auxin-overproducing superroot1 mutant of Arabidopsis thaliana". Plant Physiol. 116 (2): 687–93. doi:10.1104/pp.116.2.687. PMC   35127 . PMID   9489015.
  8. Koshiba T, Saito E, Ono N, Yamamoto N, Sato M (1996). "Purification and Properties of Flavin- and Molybdenum-Containing Aldehyde Oxidase from Coleoptiles of Maize". Plant Physiol. 110 (3): 781–789. doi:10.1104/pp.110.3.781. PMC   157777 . PMID   12226218.