| Year | Single | Peak chart positions | Certifications | Album |
|---|
US
[16] | US R&B
[17] [18] | US Dan
[19] [18] | US A/C
[20] [18] | AUS
[3] | CAN
[4] | IRE
[21] | NLD
[5] | NZ
[9] | UK
[6] |
|---|
| 1973 | "Blow Your Whistle" | — | 27 | — | — | — | — | — | — | — | — | | Do It Good |
| 1974 | "Queen of Clubs" | 66 | 25 | — | — | — | 65 | — | 9 | — | 7 | |
| "Sound Your Funky Horn" | — | 21 | — | — | — | — | — | — | — | 17 | |
| 1975 | "I'm a Pushover" | — | 57 | — | — | — | — | — | — | — | — | |
| "Get Down Tonight" | 1 | 1 | 11 | — | 44 | 1 | — | 5 | — | 21 | | KC and the Sunshine Band |
| "Shotgun Shuffle" | 88 | 25 | — | — | — | 85 | — | — | — | — | | The Sound of Sunshine |
| "That's the Way (I Like It)" | 1 | 1 | 18 | — | 5 | 1 | 17 | 1 | 12 | 4 | | KC and the Sunshine Band |
| "I'm So Crazy ('Bout You)" | — | — | — | — | — | — | — | — | — | 34 | |
| 1976 | "Rock Your Baby" | — | 70 | — | — | — | — | — | — | — | — | | The Sound of Sunshine |
| "(Shake, Shake, Shake) Shake Your Booty" | 1 | 1 | 9 | — | 16 | 1 | — | 6 | 7 | 22 | | Part 3 |
| "I Like to Do It" | 37 | 4 | — | — | 60 | — | — | 31 | — | |
| 1977 | "I'm Your Boogie Man" | 1 | 3 | — | 38 | 1 | — | 6 | 12 | 41 | |
| "Keep It Comin' Love" | 2 | 1 | 36 | 28 | 1 | — | 8 | 19 | 31 | |
| "Wrap Your Arms Around Me" | 48 | 24 | — | — | — | — | — | — | — | |
| 1978 | "Boogie Shoes" | 35 | 29 | — | — | 33 | 30 | — | — | 31 | 34 | | KC and the Sunshine Band |
| "Black Water Gold" | — | 75 | 28 | — | — | — | — | — | — | — | | — |
| "It's the Same Old Song" | 35 | 30 | — | — | 38 | 36 | — | — | — | 47 | | Who Do Ya (Love) |
| "Do You Feel All Right" | 63 | 62 | — | — | — | — | — | — | — | — | |
| "Who Do Ya Love" | 68 | 88 | — | — | — | — | — | — | — | — | |
| 1979 | "I Will Love You Tomorrow" | — | — | — | — | — | — | — | 33 | — | — | |
| "Do You Wanna Go Party" | 50 | 8 | — | — | — | 87 | — | — | — | — | | Do You Wanna Go Party |
| "Come to My Island" | — | — | — | — | — | — | — | 11 | — | — | | Who Do Ya (Love) |
| "Please Don't Go" | 1 | — | — | 27 | 1 | 1 | 5 | 7 | 3 | 3 | | Do You Wanna Go Party |
| "I Betcha Didn't Know That" | — | 25 | — | — | — | — | — | — | — | — | |
| "Yes, I'm Ready" (with Teri DeSario) | 2 | 20 | — | 1 | 30 | 10 | — | 21 | 8 | — | | Moonlight Madness |
| 1980 | "Dancin' in the Streets" (with Teri DeSario) | 66 | — | — | — | — | — | — | — | — | — | |
| "Let's Go Rock and Roll" | — | — | — | — | — | — | — | 28 | — | — | | Greatest Hits |
| "Por Favor No Te Vayas" | — | — | — | — | — | — | — | — | — | — | | — |
| "Make Me a Star" | — | — | — | — | — | — | — | — | — | — | | Space Cadet: Solo Flight |
| "Space Cadet" | — | — | — | — | — | — | — | — | — | — | |
| 1981 | "I Don't Wanna Make Love" | — | — | — | — | — | — | — | — | — | — | |
| "Love Me"/"Sway" | — | — | — | — | — | — | — | — | — | — | | The Painter |
| "It Happens Every Night" | — | — | — | — | — | — | — | — | — | — | |
| 1982 | "(You Said) You'd Gimme Some More" | — | — | 9 | — | 45 | — | 24 | — | — | 41 | | All in a Night's Work |
| "Don't Run (Come Back to Me)" (with Teri DeSario) | — | — | — | 12 | — | — | — | — | — | — | |
| 1983 | "Give It Up" | 18 | — | 24 | — | 3 | 43 | 1 | 8 | 4 | 1 | | All in a Night's Work / KC Ten |
| "Something's Happening" | — | — | — | — | — | — | — | 39 | — | — | | The Painter |
| "It's the Same Old Song" (re-release) | — | — | — | — | — | — | — | — | — | 99 | | Who Do Ya (Love) |
| 1984 | "Are You Ready" | 102 | — | — | — | — | — | — | — | — | — | | KC Ten |
| "On the Top" | — | — | — | — | — | — | — | — | — | — | |
| 1991 | "Game of Love" | — | — | — | — | — | — | — | — | — | — | | Nobody's Perfect |
| 1991 | "That's the Way (I Like It)" (The Re Mastermix) | — | — | — | — | — | — | — | — | — | 59 | | — |
| 1992 | "Please Don't Go" ('92 House Remix Version) | — | — | — | — | — | — | — | — | — | — | |
| 1993 | "Megamix (The Official Bootleg)" | — | — | — | — | — | — | — | — | — | — | | Oh Yeah! |
| "Will You Love Me in the Morning" | — | — | — | — | — | — | — | — | — | — | |
| 1994 | "Get Down and Boogie (Megamix)" | — | — | — | — | 98 | — | — | — | — | — | | — |
| 1998 | "2 Live Party" (with 2 Live Crew and Freak Nasty) | — | 52 | — | — | — | — | — | — | — | — | |
| 2001 | "I'll Be There for You" | — | — | — | — | — | — | — | — | — | — | | I'll Be There for You |
| "All That Good Stuff" | — | — | — | — | — | — | — | — | — | — | |
| "Higher Love" | — | — | — | — | — | — | — | — | — | — | |
| 2015 | "I Love You More" | — | — | 30 | — | — | — | — | — | — | — | | — |
| 2016 | "I'm Feeling You" (featuring Bimbo Jones) | — | — | 11 | — | — | — | — | — | — | — | |
| "We Belong Together" | — | — | 29 | — | — | — | — | — | — | — | |
| 2017 | "Movin' Your Body" | — | — | 38 | — | — | — | — | — | — | — | |
| 2019 | "Give Me Some More (Aye Yai Yai)"
(with Tony Moran featuring Nile Rodgers) | — | — | 12 | — | — | — | — | — | — | — | |
| 2020 | "Put a Little Love in Your Heart" | — | — | — | — | — | — | — | — | — | — | |
| 2021 | "Romantica" | — | — | — | — | — | — | — | — | — | — | |
| 2022 | "Unconditional Love" (featuring Bimbo Jones) | — | — | — | — | — | — | — | — | — | — | |
| "—" denotes a recording that did not chart or was not released in that territory. |
