L-seryl-tRNASec selenium transferase

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L-seryl-tRNASec selenium transferase
L-seryl-tRNA(Sec) selenium transferase (3W1K).png
SelA in complex with its tRNA substrate, Aquifex aeolicus PDB: 3W1K
Identifiers
EC no. 2.9.1.1
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In enzymology, a L-seryl-tRNASec selenium transferase (EC 2.9.1.1) is an enzyme that catalyzes the chemical reaction

L-seryl-tRNASec + selenophosphate L-selenocysteinyl-tRNASec + phosphate

Thus, the two substrates of this enzyme are L-seryl-tRNASec and selenophosphate, whereas its two products are L-selenocysteinyl-tRNASec and phosphate.

This enzyme belongs to the family of transferases, specifically those transferring selenium-containing groups selenotransferases. The systematic name of this enzyme class is selenophosphate:L-seryl-tRNASec selenium transferase. Other names in common use include L-selenocysteinyl-tRNASel synthase, L-selenocysteinyl-tRNASec synthase selenocysteine synthase, cysteinyl-tRNASec-selenium transferase, and cysteinyl-tRNASec-selenium transferase. This enzyme participates in selenoamino acid metabolism. It employs one cofactor, pyridoxal phosphate.

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References