| Character | Game | Release year | Role | Ethnicity | Notes | Ref. |
|---|
| Apachacha | 1993 | PC | Native American | Protagnist | [2] [3] [a] |
| The Oregon Trail | 2021 | PC | Native American | | [4] [a] |
| This Land Is My Land | 2019 | PC | Native American | Protagonist | [5] [6] [a] |
| Michael Abila | Tell Me Why | 2020 | NPC | Tlinglit | | [7] |
| Agueybana | Civilization IV: Colonization | 2008 | NPC | Arawak | | [8] [b] |
| Ajidamoo | When Rivers Were Trails | 2019 | NPC | Anishinaabe, Cree, Oneida | | [9] |
| Fareeha Amari (aka Pharah) | Overwatch | 2016 | PC | First Nations and Egyptian | | [7] |
| Anacaona | Expeditions: Conquistador | 2013 | NPC | Native American | | |
| Andar | Turok: Escape from Lost Valley | 2019 | NPC | Native American | Turok's brother | [10] [11] |
| Apache Chief | LEGO Dimensions | 2015 | | Apache | | [10] |
| Aritana | Aritana and the Harpy's Feathef | 2014 | PC | Indigenous Brazilian | | [12] [13] [14] |
| Aritana and the Twin Masks | 2019 |
| Atl | Expeditions: Conquistador | 2013 | NPC | Taíno | Shaman | [15] |
| Axe Rider | Age of Empires III: The WarChiefs | 2006 | NPC | Lakota | | [16] [17] [c] |
| Ayabe | When Rivers Were Trails | 2019 | NPC | Anishinaabe, Cree, Oneida | | [9] |
| Bella | When Rivers Were Trails | 2019 | NPC | Anishinaabe, Cree, Oneida | | [9] |
| Bimibisa | When Rivers Were Trails | 2019 | NPC | Anishinaabe, Cree, Oneida | | [9] |
| Amelia Black | Age of Empires III: The WarChiefs | 2006 | NPC | Iroquois and Scottish | Nathaniel Black's daughter | [18] |
| Chayton Black | Age of Empires III: The WarChiefs | 2006 | PC | Iroquois, Scottish, and Lakota-Sioux | Nathaniel Black's grandson | [18] |
| Nathaniel Black | Age of Empires III: The WarChiefs | 2006 | PC | Iroquois and Scottish | | [18] |
| Blackwood Archer | Age of Empires III: The WarChiefs | 2006 | NPC | Tupi | | [16] [c] |
| Blowgunner | Age of Empires III: The WarChiefs | 2006 | NPC | Kalinago | | [16] [c] |
| Bolas Warrior | Age of Empires III: The WarChiefs | 2006 | NPC | Inca | | [16] [c] |
| Brave | Brave: The Search for Spirit Dancer | 2005 | PC | Native American | Protagonist; playable as a male or female | [19] [20] [21] |
| Brave: A Warrior's Tale | 2009 |
| Cacama | Expeditions: Conquistador | 2013 | NPC | Native American | | |
| Calm Water | Call of Juarez | 2006 | NPC | Apache | Chief | |
| Casiguaya | Expeditions: Conquistador | 2013 | NPC | Native American | | |
| Julia Chang | Tekken 3 | 1997 | PC | Native American and Chinese | | [10] [22] |
| Michelle Chang | Tekken | 1994 | PC | Native American and Chinese | | [7] |
| Chief Macalosh "Wild One" | Dangerous Streets | 1993 | PC | Sioux | Spiritual leader | [23] |
| Chief Scalpem (aka Wigwam) | Sunset Riders | 1991 | NPC | Native American | | [10] |
| Chief Thunder (aka hinnamatoom) | Killer Instinct | 1994 | PC | Nez Perce | | [10] [24] [22] |
| Killer Instinct | 2013 |
| Citlalli | Expeditions: Conquistador | 2013 | NPC | Native American | | |
| Clubman | Age of Empires III: The WarChiefs | 2006 | NPC | Nootka | | [16] [c] |
| Code Talker | Metal Gear Solid V: The Phantom Pain | 2015 | NPC | Navajo | | [25] |
| Mangas Coloradas | Civilization IV: Colonization | 2008 | NPC | Apache | | [8] [b] |
| Condor Heads | Breakers | 1996 | PC | Native American | | [10] |
| Coyotl | Expeditions: Conquistador | 2013 | NPC | Native American | | |
| Crazy Horse | Age of Empires III: The WarChiefs | 2006 | NPC | Lakota | | [18] [b] |
| Cuauhtemoc | Age of Empires III: The WarChiefs | 2006 | PC | Aztec | War Chief | [17] [b] |
| Cunhambebe | Civilization IV: Colonization | 2008 | NPC | Tupi | | [8] [b] |
| Cyborg 005 | Cyborg 009 | 1994 | | Native American | | [10] |
| Dances with Barlog | MapleStory | 2003 | NPC | Native American | | [10] |
| Devil Hawk | Gun.Smoke | 1985 | NPC | Comanche | | [10] |
| Eagle (aka tipyeléhne) | Killer Instinct | 1994 | PC | Nez Perce | Thunder's brother | [10] [26] [27] |
| Killer Instinct | 2013 |
| Eagle Flies | Red Dead Redemption 2 | 2018 | NPC | Wapiti (fictional) | Rains Falls' son | [10] [28] |
| Paul Eagle Star | When Rivers Were Trails | 2019 | NPC | Anishinaabe, Cree, Oneida | | [9] |
| Eagle Warrier | Age of Empires III: The WarChiefs | 2006 | NPC | Aztec | | [16] [c] |
| Anna Elk Moon | Santa Fe Mysteries: The Elk Moon Murder | 1996 | NPC | Native American | Famous artist (fictional) | |
| Enisi | Prey | 2006 | NPC | Cherokee | Domasi "Tommy" Tawodi's grandfather | [29] [4] |
| David Falk | Dino Crisis 2 | 2000 | | Native American | | [10] |
| Falling Star | Red Dead Revolver | 2004 | NPC | Red Wolf (fictional) | | [10] |
| Fights-At-Dawn | Gun | 2005 | NPC | Blackfoot | Chief | [30] |
| Danielle Fireseed | Turok 3: Shadow of Oblivion | 2000 | PC | Native American | | [10] |
| Joshua Fireseed | Turok 2: Seeds of Evil | 1998 | PC | Native American | | [7] [19] |
| Turok: Rage Wars | 1999 |
| Turok 3: Shadow of Oblivion | 2000 |
| Turok | 2008 |
| Floyd | Rochard | 2011 | NPC | Native American | Skyler Hanson's uncle | |
| Forest Prowler | Age of Empires III: The WarChiefs | 2006 | NPC | Iroquois | | [17] [c] |
| Gall | Age of Empires III: The WarChiefs | 2006 | PC | Sioux | Chief | [17] [b] |
| Galuda | Power Stone | 1999 | PC | Native American | Shaman | [10] |
| Grey Wolf | Call of Juarez: Gunslinger | 2013 | NPC | Apache | Chief | |
| Red Harlow | Red Dead Revolver | 2004 | PC | Half Native American | Protagonist | [19] |
| Huayna Capac | Civilization IV: Colonization | 2008 | NPC | Incas | | [8] [b] |
| Thunder Hawk | Super Street Fighter II Turbo | 1994 | PC | Thunderfoot (fictional) | | [22] [31] |
| Street Fighter Alpha 3 | 1998 |
| Ultra Street Fighter II: The Final Challengers | 2017 |
| Super Street Fighter IV | 2018 |
| Wolf Hawkfield | Virtua Fighter | 1993 | PC | First Nations | | [31] [22] |
| Fighters Megamix | 1996 |
| Hiawatha | Age of Empires III: The WarChiefs | 2006 | PC | Iroquois | War Chief | [17] [b] |
| Meeygen Hill | Hill Agency: PURITYdecay | 2023 | PC | Néhinaw | | [32] |
| Holcan Spearman | Age of Empires III: The WarChiefs | 2006 | NPC | Maya | | [16] [c] |
| Horse Runner | Age of Empires III: The WarChiefs | 2006 | NPC | Comanche | | [16] [c] |
| Huaminca | Age of Empires III: The WarChiefs | 2006 | NPC | Inca | | [16] |
| Huayna Capac | Age of Empires III: The WarChiefs | 2006 | PC | Inca | | |
| Humba Wumba | Banjo-Tooie | 2000 | NPC | Native American | Woman shaman | [10] |
| Banjo-Kazooie: Nuts & Bolts | 2008 |
| Iron Tail | Buffalo Bill's Wild West Show | 1989 | PC | Oglala Lakota | Chief | [b] |
| Isabela | Expeditions: Conquistador | 2013 | NPC | Taíno and Spanish | | [15] |
| Jaguar Warrier | Age of Empires III: The WarChiefs | 2006 | NPC | Aztec | | [16] [c] |
| Janitor | Elvira II: The Jaws of Cerberus | 1992 | NPC | Native American | | [33] |
| Jen | Prey | 2006 | NPC | Cherokee | Domasi "Tommy" Tawodi's girlfriend | [4] |
| Kahhori | Marvel Future Fight | 2015 | | Mowhawk | | [7] |
| Kanenʼtó꞉kon | Assassin's Creed III | 2012 | NPC | Mohawk | | |
| Kaniehtí꞉io (aka Ziio) | Assassin's Creed III | 2012 | NPC | Mohawk | | [31] |
| Kanya Horseman | Age of Empires III: The WarChiefs | 2006 | NPC | Iroquois | | [17] [c] |
| Kesegowaase | Assassin's Creed Rogue | 2014 | NPC | Abenaki | | [7] |
| Lady Six Sky | Civilization VI | 2016 | PC | Maya | Leader | [34] [b] |
| Lakota Dog Soldier | Age of Empires III: The WarChiefs | 2006 | NPC | Lakota | | [16] [c] |
| Lautaro | Civilization VI: Rise and Fall | 2018 | PC | Mapuche | | [35] [b] |
| Lily | Street Fighter 6 | 2023 | PC | Thunderfoot (fictional) | | [7] |
| Little Chief | Cowboy Kid | 1991 | NPC | Native American | | |
| Logan | Civilization IV: Colonization | 2008 | NPC | Iroquois | | [8] [b] |
| Lynetta | Cherokee Trails | 2002 | PC | Cherokee | | |
| Makwa | When Rivers Were Trails | 2019 | NPC | Anishinaabe, Cree, Oneida | | [9] |
| Man-of-Bats | Scribblenauts Unmasked: A DC Comics Adventure | 2013 | NPC | Lakota | Chief | [7] |
| Man Running | Empire of Sin: Taking Chicago | 2020 | PC | Native American | Gangster | |
| Many Wounds | Gun | 2005 | NPC | Apache | | [36] |
| Desmond Miles | Assassin's Creed | 2007 | PC | Mohawk and English | Protagonist | [37] [38] [19] |
| Assassin's Creed II | 2009 |
| Assassin’s Creed: Brotherhood | 2010 |
| Assassin’s Creed: Revelations | 2010 |
| Assassin's Creed III | 2012 |
| Montezuma II | Civilization IV: Colonization | 2008 | NPC | Aztec | | [8] [39] [b] |
| Civilization VI | 2016 | PC |
| Nahova | Tao Taido | 1993 | PC | Native American | Warrior | [7] |
| Nastas | Red Dead Redemption | 2010 | NPC | Native American | | [7] [19] |
| Natan | Shadow Hearts: From the New World | 2005 | PC | Garvoy (fictional) | | [40] [22] |
| Necalli | Expeditions: Conquistador | 2013 | NPC | Native American | | |
| Nightwolf | Mortal Kombat 3 | 1995 | PC | Matoka (fictional) | | [22] [7] |
| Mortal Kombat: Deception ; | 2004 |
| Mortal Kombat: Armageddon | 2006 |
| Mortal Kombat 11 | 2019 |
| Noembelu (aka Little Eagle) | Street Fighter Alpha 3 | 1998 | PC | Thunderfoot (fictional) | | [7] |
| Nuna | Never Alone | 2014 | PC | Iñupiaq | | [41] [4] |
| Oconostota | Civilization IV: Colonization | 2008 | NPC | Cherokee | | [8] [b] |
| Oiá꞉ner | Assassin's Creed III | 2012 | NPC | Mohawk | | |
| Opía Apito | Assassin's Creed IV: Black Flag | 2013 | NPC | Taíno | | |
| Oshiki-inini | When Rivers Were Trails | 2019 | NPC | Anishinaabe, Cree, Oneida | | [9] |
| Owlwoman | Scribblenauts Unmasked: A DC Comics Adventure | 2013 | NPC | Cherokee | | [7] |
| Pachacuti | Civilization VI | 2016 | PC | Incan | | [39] [42] [b] |
| Civilization VII | 2025 |
| Pakawa | Kasumi Ninja | 1994 | PC | Comanche Tu-Wee-Kah | | [7] |
| Patli | Expeditions: Conquistador | 2013 | NPC | Native American | | |
| Player 2 | Blood Bros. | 1990 | PC | Native American | | [43] [44] [a] |
| Pocahontas | Legend of Pocahontas | 2002 | PC | Powhatan | | [45] [7] [b] |
| Pocahontas (Disney) | Pocahontas: Riverbend Adventures | 1995 | NPC, PC | Powhatan | | [45] [7] [b] |
| Disney's Animated Storybook: Pocahontas | 1995 | |
| Disney's Pocahontas | 1996 |
| Disney Tsum Tsum | 2014 |
| Disney Emoji Blitz | 2016 |
| Disney Magic Kingdoms | 2016 |
| Disney Heroes: Battle Mode | 2018 |
| Disney Sorcerer’s Arena | 2020 |
| Pontiac | American Conquest: Fight Back | 2002 | NPC | Odawa | | [b] |
| Poundmaker | Civilization VI | 2016 | PC | Plains Cree | Leader | [7] [39] [b] |
| Puma Spearman | Age of Empires III: The WarChiefs | 2006 | NPC | Aztec | | [17] [c] |
| Rains Falls | Red Dead Redemption 2 | 2018 | NPC | Wapiti (fictional) | Chief and father of Eagle Flies | [7] [28] |
| Ratonhnhaké:ton (aka Connor Kenway) | Assassin's Creed III | 2012 | PC | Mohawk and English | Protagonist | [10] [41] [22] [46] [19] [47] [48] |
| Assassin's Creed III: The Tyranny of King Washington |
| Raven | Nightmare Circus | 1996 | PC | Native American | | [49] |
| Raven Red | Scribblenauts Unmasked: A DC Comics Adventure | 2013 | NPC | Lakota | Man-of-Bats' son | [7] |
| Red Cloud | Age of Empires III: The WarChiefs | 2006 | NPC | Lakota | | [18] [b] |
| Red Leaf | When Rivers Were Trails | 2019 | NPC | Anishinaabe, Cree, Oneida | | [9] |
| Rifle Ridger | Age of Empires III: The WarChiefs | 2006 | PC | Sioux | | [17] [c] |
| Rifleman | Age of Empires III: The WarChiefs | 2006 | NPC | Cherokee | | [16] [c] |
| Delsin Rowe | Infamous Second Son | 2014 | PC | Akomish (fictional) | | [10] [46] [19] [d] |
| Reggie Rowe | Infamous Second Son | 2014 | NPC | Akomish (fictional) | Delsin Rowe's brother | [50] |
| Running Moon | Red Dead Revolver | 2004 | NPC | Red Wolf (fictional) | Chief | [51] |
| Running River (aka Calm Water | Call of Juarez: Bound in Blood | 2009 | NPC | Apache | Chief | |
| Scout | Age of Empires III: The WarChiefs | 2006 | NPC | Native American | | [16] [c] |
| Seeing Farther | Call of Juarez: Bound in Blood | 2009 | NPC | Apache | Running River's son | |
| Shadow Wolf | Red Dead Revolver | 2004 | NPC | Red Wolf (fictional) | Red Harlow's cousin | [7] [19] |
| Red Dead Redemption | 2010 |
| Shania | Shadow Hearts: From the New World | 2005 | PC | Garvoy (fictional) | | [22] |
| Sharktooth Bowman | Age of Empires III: The WarChiefs | 2006 | NPC | Iroquois | | [16] |
| Singing Elk | When Rivers Were Trails | 2019 | NPC | Anishinaabe, Cree, Oneida | | [9] |
| Sitting Bull | Civilization IV: Beyond the Sword | 2007 | PC | Sioux | | [52] [8] [b] |
| Civilization IV: Colonization | 2008 | NPC |
| Sitting Bull | Age of Empires III: The WarChiefs | 2006 | NPC | Lakota | | [18] [b] |
| Skull Knight | Age of Empires III: The WarChiefs | 2006 | NPC | Aztec | | [17] |
| Small Bear | When Rivers Were Trails | 2019 | NPC | Anishinaabe, Cree, Oneida | | [9] |
| Charles Smith | Red Dead Redemption 2 | 2018 | NPC | Native American and African American | | [10] [46] |
| Soaring Eagle | Whomp 'Em | 1991 | PC | Native American | Protagonist | [7] [19] |
| Spirit Dancer | Brave: The Search for Spirit Dancer | 2005 | NPC | Native American | Shaman | [21] |
| Rick Strowd | Real Bout Fatal Fury 2: The Newcomers | 1998 | PC | Native American and Caucasian | | [22] |
| Sukurúame | Mulaka | 2018 | PC | Tarahumara | Shaman | [53] |
| Tala | Darkwatch: Curse of the West | 2005 | NPC | Native American | Vampire | [7] |
| Tal'Set (aka Turok) | Turok: Dinosaur Hunter | 1997 | PC | Native American | | [31] [46] [19] [54] [11] [e] |
| Turok: Battle of the Bionosaurs ; | 1997 |
| Turok: Evolution | 2002 |
| Turok: Escape from Lost Valley | 2019 |
| Domasi "Tommy" Tawodi | Prey | 2006 | PC | Cherokee | | [22] [46] [19] [31] [4] |
| Prey Mobile 3D | 2007 |
| Tayanna | Expeditions: Conquistador | 2013 | NPC | Native American | | |
| Tecumseh | Civilization VII | 2025 | PC | Shawnee | Chief and warrior | [55] [b] |
| Tiger Lily | Code Name: S.T.E.A.M. | 2015 | PC | Piccaninny (fictional) | | [31] |
| Tomahawk Warrior | Age of Empires III: The WarChiefs | 2006 | NPC | Iroquois | | [16] [c] |
| Tonto | The Lone Ranger | 1991 | NPC | Native American | Lone Ranger's partner | [31] |
| Totec | Lara Croft and the Guardian of Light | 2010 | NPC | Mayan | | [56] |
| Tracker | Age of Empires III: The WarChiefs | 2006 | NPC | Cree | | [16] [c] |
| Two Feathers | Outlaws | 1997 | NPC | Native American | | |
| Uncle Kanyenke | Age of Empires III: The WarChiefs | 2006 | NPC | Iroquois | | [18] [16] |
| Vulcan Raven | Metal Gear Solid | 1998 | NPC | Alaska native and Inuit | | [31] [22] |
| Wabishkio | When Rivers Were Trails | 2019 | NPC | Anishinaabe, Cree, Oneida | | [9] |
| Wakina Rifleman | Age of Empires III: The WarChiefs | 2006 | PC | Sioux | | [17] [c] |
| Wakosh | When Rivers Were Trails | 2019 | NPC | Anishinaabe, Cree, Oneida | | [9] |
| Wasu Maza | When Rivers Were Trails | 2019 | NPC | Anishinaabe, Cree, Oneida | | [9] |
| Colton White | Gun | 2005 | PC | Apache and Caucasian | Protagonist | [10] [19] |
| Gun: Showdown | 2006 |
| Wild Wolf Chief | Cowboy Kid | 1991 | NPC | Native American | | [19] |
| Wolf Chief | Gun.Smoke | 1985 | NPC | Native American | | [57] |
| Yakari | Yakari: The Mystery of Four Seasons | 2015 | PC | Native American | Protagonist | [58] |
| Yuno | Tengai Makyō: Daiyon no Mokushiroku | 1997 | PC | Native American | Warrior from Seattle | |