| Name | Developer | Publisher | Genre(s) | Operating system(s) | Date released |
|---|
| M.U.D. TV | Realmforge Studios | Kalypso Media | Business simulation | Microsoft Windows | February 23, 2010 |
| M.U.G.E.N | ElecByte | ElecByte | Fighting | MS-DOS, Microsoft Windows, Linux, macOS | July 17, 1999 |
| M1 Tank Platoon | MPS Labs | MicroProse | Simulation, real-time tactics | Amiga, Atari ST, MS-DOS | 1989 |
| M1 Tank Platoon II | MicroProse | MicroProse | Simulation, real-time tactics | Microsoft Windows | February 28, 1998 |
| Magicka | Arrowhead Game Studios | Paradox Interactive | Fantasy, action-adventure | Microsoft Windows | January 25, 2011 |
| Mass Effect | BioWare Corporation | Electronic Arts | RPG, Action, science fiction | Microsoft Windows | November 20, 2007 |
| Mass Effect 2 | BioWare Corporation | Electronic Arts | RPG, action, science fiction | Microsoft Windows | January 26, 2010 |
| Mass Effect 3 | BioWare Corporation | Electronic Arts | RPG, action, science fiction | Microsoft Windows | March 6, 2012 |
| Max Payne | Remedy Entertainment | Gathering of Developers, Rockstar Games, MacSoft, Feral Interactive | Third-person shooter | Microsoft Windows, macOS | July 23, 2001 |
| Max Payne 2: The Fall of Max Payne | Remedy Entertainment | Rockstar Games | Third-person shooter | Microsoft Windows | October 14, 2003 |
| MDK | Shiny Entertainment | PIE, Interplay Entertainment | Third-person shooter | Microsoft Windows, MS-DOS, macOS | November 21, 1997 |
| MDK2 | BioWare | Interplay Entertainment | Third-person shooter, action-adventure | Microsoft Windows | March 31, 2000 |
| Mechwarrior Online | Piranha Games | Piranha Games | Vehicular combat, action | Microsoft Windows | September 17, 2013 |
| Medal of Honor | DICE, Danger Close Games | Electronic Arts | First-person shooter | Microsoft Windows | October 8, 2010 |
| Medal of Honor: Warfighter | Danger Close Games | Electronic Arts | First-person shooter | Microsoft Windows | October 23, 2012 |
| Medieval: Total War | The Creative Assembly | Activision | Turn-based strategy | Microsoft Windows | August 20, 2002 |
| Medieval II: Total War | The Creative Assembly | Sega | Turn-based strategy | Microsoft Windows | November 11, 2006 |
|
| MegaRace | Cryo Interactive | The Software Toolworks | Racing video game | MS-DOS | 1993 |
|
| MegaRace 2 | Cryo Interactive | Mindscape | Racing video game | MS-DOS, macOS | 1996 |
|
| MegaRace 3 | Cryo Interactive | Cryo Interactive, DreamCatcher Interactive | Racing video game | Microsoft Windows | January 9, 2002 |
| Metal Gear | Konami | Konami | Action-adventure, stealth | MSX2, MS-DOS | July 7, 1987 |
| Metal Gear 2: Solid Snake | Konami | Konami | Action-adventure, stealth | MSX2 | July 20, 1990 |
| Metal Gear Rising: Revengeance | PlatinumGames | Konami | Action, hack and slash | Microsoft Windows | January 9, 2014 |
| Metal Gear Solid | KCEJ, Digital Dialect | Konami, Microsoft Game Studios | Action-adventure, stealth | Microsoft Windows | September 3, 1998 |
| Metal Gear Solid 2: Substance | KCEJ, Success | Konami | Action-adventure, stealth | Microsoft Windows | March 27, 2003 |
| Metal Gear Solid V: Ground Zeroes | Kojima Productions | Konami | Action-adventure, stealth | Microsoft Windows | September 1, 2015 |
| Metal Gear Solid V: The Phantom Pain | Kojima Productions | Konami | Action-adventure, stealth | Microsoft Windows | September 1, 2015 |
| Metro 2033 | 4A Games | Deep Silver, THQ | Post-apocalyptic, FPS | Microsoft Windows, Linux | March 16, 2010 |
| Metro: Last Light | 4A Games | Spike Chunsoft, Deep Silver | Post-apocalyptic, FPS | Microsoft Windows, Linux, macOS | May 14, 2013 |
| Microsoft Minesweeper | Arkadium | Microsoft Studios | | Microsoft Windows | 2012 |
| Middle-earth: Shadow of Mordor | Monolith | Warner Bros. | Action-adventure | Microsoft Windows, Linux, macOS | September 30, 2014 |
| Might & Magic X: Legacy | Limbic Entertainment | Ubisoft | RPG, action RPG | Microsoft Windows | January 23, 2014 |
| Might and Magic VI | New World Computing | 3DO | RPG, action RPG | Microsoft Windows | April 30, 1998 |
| Might and Magic VII | New World Computing | 3DO | RPG, action RPG | Microsoft Windows | May 15, 1999 |
| A Mind Forever Voyaging | Infocom | Infocom | Interactive fiction | Amiga, Apple II, Atari ST, Commodore 128, MS-DOS, macOS | August 14, 1985 |
| Minecraft | Mojang | Mojang | Sandbox | Microsoft Windows, Linux, macOS, Raspberry Pi | November 18, 2011 |
| Minecraft: Story Mode | Mojang | Mojang | Graphic adventure | Microsoft Windows, macOS | October 13, 2015 |
| Mirror's Edge | EA Digital Illusions CE | Electronic Arts | First-person action-adventure, platform | Microsoft Windows | November 12, 2008 |
| Monaco: What's Yours Is Mine | Pocketwatch Games | Majesco Entertainment | Action, stealth | Microsoft Windows, Linux, macOS | April 24, 2013 |
| Mortal Kombat (2011) | NetherRealm Studios, High Voltage Software | Warner Bros. Interactive Entertainment. | Fighting | Microsoft Windows | April 19, 2011 |
| Mortal Kombat X | NetherRealm Studios, High Voltage Software, QLOC | Warner Bros. Interactive Entertainment. | Fighting | Windows | April 13, 2015 |
| Mortal Kombat 11 | NetherRealm Studios, QLOC | Warner Bros. Interactive Entertainment. | Fighting | Windows | April 23, 2019 |
| Mount & Blade | TaleWorlds Entertainment | Paradox Interactive | Action RPG | Microsoft Windows | September 16, 2008 |
| Mount & Blade: Warband | TaleWorlds Entertainment | Paradox Interactive | Action RPG, strategy | Microsoft Windows, Linux, macOS | March 30, 2010 |
| Mount & Blade: With Fire & Sword | TaleWorlds Entertainment | Paradox Interactive | Action RPG, strategy | Microsoft Windows | May 3, 2011 |
| MouseCraft | Crunching Koalas | Crunching Koalas | Puzzle | Microsoft Windows, Linux, macOS | June 9, 2014 |
| MVP Baseball 2005 | EA Canada | Electronic Arts | Sports | Microsoft Windows | February 22, 2005 |
| Myst | Cyan | Broderbund | Adventure | Mac OS, Windows | 1994 |
| Myth Makers: Super Kart GP | Data Design Interactive | Phoenix Games | Racing video game | Windows | January 1, 2006 |
| Myth Makers: Trixie in Toyland | Data Design Interactive | Metro3D Europe | Platformer | Microsoft Windows | August 19, 2005 |