Methylphosphonate synthase

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Methylphosphonate synthase
Identifiers
EC no. 1.13.11.73
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
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PMC articles
PubMed articles
NCBI proteins

Methylphosphonate synthase (EC 1.13.11.73, mpnS (gene)) is an enzyme with systematic name 2-hydroxyethylphosphonate:O2 1,2-oxidoreductase (methylphosphonate forming). [1] This enzyme catalyses the following chemical reaction:

 
O2
H2CO3
Methylphosphonate synthase
 
 
 

The carbon atom which is removed from 2-hydroxyethylphosphonic acid becomes carbonic acid. [2] Methylphosphonate synthase is isolated from the marine archaeon Nitrosopumilus maritimus .

References

  1. Metcalf WW, Griffin BM, Cicchillo RM, Gao J, Janga SC, Cooke HA, Circello BT, Evans BS, Martens-Habbena W, Stahl DA, van der Donk WA (August 2012). "Synthesis of methylphosphonic acid by marine microbes: a source for methane in the aerobic ocean". Science. 337 (6098): 1104–7. Bibcode:2012Sci...337.1104M. doi:10.1126/science.1219875. PMC   3466329 . PMID   22936780.
  2. Enzyme 1.13.11.73 at KEGG Pathway Database.