Multicenter AIDS Cohort Study

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The Multicenter AIDS Cohort Study (MACS) is an ongoing cohort study involving over 6,000 men, including both those infected with HIV, as well as HIV-negative men. The MACS has four main sites: Baltimore, Pittsburgh, Los Angeles, and Chicago. The Los Angeles component of the MACS is called the Los Angeles Mens Study or LAMS. LAMS affiliated with UCLA and is supervised by Dr Roger Detels, MD & John Oishi.[ citation needed ]

The study, a program of the Division of Acquired Immunodeficiency Syndrome, has been ongoing since 1984 and has resulted in over 1,000 scientific publications. It helped to establish that AIDS was the result of a viral illness and how HIV was spread. Participants were quizzed in detail about their sexual behavior. "They ask you for numbers, how many times did you do what." Some participants who had many sexual partners were not infected, and this led to the realization that some people had genetic resistance to the virus. [1] [2]

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Since reports of emergence and spread of the human immunodeficiency virus (HIV) in the United States between the 1970s and 1980s, the HIV/AIDS epidemic has frequently been linked to gay, bisexual, and other men who have sex with men (MSM) by epidemiologists and medical professionals. It was first noticed after doctors discovered clusters of Kaposi's sarcoma and pneumocystis pneumonia in homosexual men in Los Angeles, New York City, and San Francisco in 1981. The first official report on the virus was published by the Center for Disease Control (CDC) on June 5, 1981 and detailed the cases of five young gay men who were hospitalized with serious infections. A month later, The New York Times reported that 41 homosexuals had been diagnosed with Kaposi's sarcoma, and eight had died less than 24 months after the diagnosis was made.

David DuPuy Celentano is a noted epidemiologist and professor who has contributed significantly to the promotion of research on HIV/AIDS and other sexually transmitted infections (STIs). He is the Charles Armstrong chair of the Department of Epidemiology at the Johns Hopkins Bloomberg School of Public Health. He holds joint appointments with the school’s departments of Health Policy and Management, Health Behavior and Society, and International Health, and the Johns Hopkins University School of Medicine’s Division of Infectious Diseases.

References

  1. Brenda Wilson (April 24, 2009), AIDS Study Marks 25th Year, National Public Radio
  2. Multicenter AIDS Cohort Study, May 2006