Music-specific disorders

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Neuroscientists have learned much about the role of the brain in numerous cognitive mechanisms by understanding corresponding disorders. Similarly, neuroscientists have come to learn much about music cognition by studying music-specific disorders. Even though music is most often viewed from a "historical perspective rather than a biological one" [1] music has significantly gained the attention of neuroscientists all around the world. For many centuries music has been strongly associated with art and culture. The reason for this increased interest in music is because it "provides a tool to study numerous aspects of neuroscience, from motor skill learning to emotion". [1]

Contents

Overview

An important technique that is used by neuroscientists in understanding the cognition of music involves understanding musical disorders. This article describes some of the disorders that have been identified by neuroscientists. They range from disorders involving pitch, rhythm and melody, playing instruments and creating music. This article explores two of the most commonly found music related disorders—(1)

Definitions: basic musical concepts

Before delving into the disorders related to music, it is important to have a basic understanding of the following terms:

Pitch

In the physical sense of the term, the word "pitch" refers to the frequency of a sound. Another term that is frequently used by music neuroscientists is "fine-grained pitch processing" which refers to the ability of a person to distinguish minor changes or fluctuations in pitch. Processing pitch is an extremely integral part of music cognition. Recent developments in brain scanning techniques have shown neuroscientists that the posterior secondary cortex plays an extremely important part in the processing of pitch in the brain. [2] In music, "pitch relation" is more important than pitch itself. A subset of five to seven pitches creates a scale. The scale tones are "not equivalent and are organized around a central tone, called the tonic" (Peretz 2005).

Time relations

Temporal organization of music is commonly referred to as "rhythm". In 1982 the neuroscientist Fraisse claimed that there are mainly two types of time relations that are fundamental to musical temporal organization: (1) "the segmentation of an ongoing sequence into temporal groups" based on the duration values (in musical terms a whole, half, quarter, eighth or sixteenth note), and (2) "extraction of an underlying temporal regularity or beat". [3]

In the brain, it is believed that the right hemisphere better handles meter, while the left hemisphere better handles rhythm. Scientists have studied patients with brain lesions in their right temporal auditory cortex and realized that they were unable to "tap a beat or generate a steady pulse". [4]

Timbre

"Timbre" refers to the quality of a musical note that enables us to distinguish between different kinds of sound production. It is the characteristic of music that helps us recognize an instrument or source of a particular sound—such as a piano, saxophone, or a flute.

Memory

It is important to note that music unfolds over time, thus the "auditory cognitive system must depend to a large degree on mechanisms that allow a stimulus to be maintained on-line to be able to relate one element in a sequence to another that occurs later" (Peretz 2005). Research has shown that working memory mechanisms for pitch information over a short period of time may be different from those involved in speech. In addition to the role that auditory cortices play in working memory for music, neuroimaging and lesion studies prove that frontal cortical areas also play an important role. [5]

Emotion

Music is not merely "limited to perception and memory", but is also closely related to emotion. The mode of music (major or minor), and the tempo of a song (fast or slow) can invoke joy or sorrow in the listener. [6] In the brain, emotional analysis is carried out by "a common cortical relay, suggesting no direct access to subcortical, limbic structures". [7]

Musical disorders

Music-specific disorders may be acquired or congenital Music Disorders.jpg
Music-specific disorders may be acquired or congenital

With a growing interest in music cognition amongst neuroscientists, music-specific disorders are becoming more relevant in research and in understanding music processing in the brain. Several music-specific disorders have been identified, with causes ranging from congenital to acquired (specific lesions in the brain).

Amusia

Definition and history

Amusia refers to the inability of certain individuals to recognize simple tunes. [8] Amusia is commonly referred to as tone-deafness, tune-deafness, dysmelodia, or dysmusia. The first documented case of congenital amusia was reported in 2002 by music neuroscientists from the Department of Psychology at the University of Montreal, Canada. The case followed the case of a middle-aged woman who "lacks most basic musical abilities". [9] Some of the techniques that are used in studying this disorder are functional magnetic resonance imaging (fMRI), positron emission tomography or PET scans, and anatomical MRI.

Symptoms and causes

Amusia may be congenital or acquired. Congenital amusia, as the term suggests, occurs as a result of birth or one's genes; while acquired amusia occurs as a result of accidental brain damage, stress, or cognitive deficits. Symptoms of this disease vary from lack of basic melodic discrimination, recognition despite normal audiometry, above average intellectual, memory, as well as language skills (Peretz 2002). Another conspicuous symptom of amusia is the ability of the affected individual to carry out normal speech, however, he or she is unable to sing. Amusic individuals "show a particular deficit in discriminating musical pitch variations and in recognizing familiar melodies". [10] Neuroscientists are now classifying congenital amusia as a "new class of learning disabilities that affect musical abilities" (Ayotte 2002).

Acquired music agnosia

Definition

The term "agnosia" refers to a loss of knowledge. Acquired music agnosia is the "inability to recognize music in the absence of sensory, intellectual, verbal, and mnesic impairments". [11] Music agnosia is most commonly acquired; in most cases it is a result of bilateral infarction of the right temporal lobes. [12] [ clarification needed ] In his article, Satoh states "when pure word deafness, auditory sound agnosia, and receptive amusia occur simultaneously, the state is called auditory agnosia" (Satoh 2007). However, one must understand the subtle difference between auditory and music agnosia; the former refers to the inability to recognize environmental sounds while the latter refers to the inability to recognize music. [13]

Symptoms and causes

The main symptoms of music agnosia range from the inability to recognize pitch, rhythm, chords, and notes to the inability to discriminate and recognize familiar songs, and judge tonality, and reproduce musical phrases. As was previously mentioned the main causes for music agnosia are lesions in the right or bilateral temporal lobes (Satoh 2007) or unilateral strokes.

Musical hallucinations

Definition

Musical hallucinations (MH) can be described as perceptions of musical sounds in the absence of external auditory stimuli. Although imagined sounds can be non-musical; such as bells, whistles and sirens, case studies indicate that music "[takes] precedence over all other auditory hallucinations" (Sacks, 2006). Furthermore, MH may often take the form of songs from childhood and may be connected with strong childhood emotions.

Symptoms and causes

In a literature review by Evers and Ellger (2004), manifestations of MH can also be attributed to: a) psychiatric disorder, b) brain lesion, c) epilepsy and d) intoxication. Of great interest to researchers are individuals who experience MH with focal lesions and epileptic brain activity. Until recently, neurologists believed in a hemispheric dominance theory of music. Brain scans of subjects with lesions seem to refute this notion. Evers and Ellger (2004) found no significant difference in the hemisphere associated with the lesion as the major cause of MH.

See also

Related Research Articles

<span class="mw-page-title-main">Agnosia</span> Medical condition

Agnosia is the inability to process sensory information. Often there is a loss of ability to recognize objects, persons, sounds, shapes, or smells while the specific sense is not defective nor is there any significant memory loss. It is usually associated with brain injury or neurological illness, particularly after damage to the occipitotemporal border, which is part of the ventral stream. Agnosia only affects a single modality, such as vision or hearing. More recently, a top-down interruption is considered to cause the disturbance of handling perceptual information.

<span class="mw-page-title-main">Temporal lobe</span> One of the four lobes of the mammalian brain

The temporal lobe is one of the four major lobes of the cerebral cortex in the brain of mammals. The temporal lobe is located beneath the lateral fissure on both cerebral hemispheres of the mammalian brain.

<span class="mw-page-title-main">Auditory cortex</span> Part of the temporal lobe of the brain

The auditory cortex is the part of the temporal lobe that processes auditory information in humans and many other vertebrates. It is a part of the auditory system, performing basic and higher functions in hearing, such as possible relations to language switching. It is located bilaterally, roughly at the upper sides of the temporal lobes – in humans, curving down and onto the medial surface, on the superior temporal plane, within the lateral sulcus and comprising parts of the transverse temporal gyri, and the superior temporal gyrus, including the planum polare and planum temporale.

Auditory imagery is a form of mental imagery that is used to organize and analyze sounds when there is no external auditory stimulus present. This form of imagery is broken up into a couple of auditory modalities such as verbal imagery or musical imagery. This modality of mental imagery differs from other sensory images such as motor imagery or visual imagery. The vividness and detail of auditory imagery can vary from person to person depending on their background and condition of their brain. Through all of the research developed to understand auditory imagery behavioral neuroscientists have found that the auditory images developed in subjects' minds are generated in real time and consist of fairly precise information about quantifiable auditory properties as well as melodic and harmonic relationships. These studies have been able to recently gain confirmation and recognition due to the arrival of Positron emission tomography and fMRI scans that can confirm a physiological and psychological correlation.

Amusia is a musical disorder that appears mainly as a defect in processing pitch but also encompasses musical memory and recognition. Two main classifications of amusia exist: acquired amusia, which occurs as a result of brain damage, and congenital amusia, which results from a music-processing anomaly present since birth.

Auditory verbal agnosia (AVA), also known as pure word deafness, is the inability to comprehend speech. Individuals with this disorder lose the ability to understand language, repeat words, and write from dictation. Some patients with AVA describe hearing spoken language as meaningless noise, often as though the person speaking was doing so in a foreign language. However, spontaneous speaking, reading, and writing are preserved. The maintenance of the ability to process non-speech auditory information, including music, also remains relatively more intact than spoken language comprehension. Individuals who exhibit pure word deafness are also still able to recognize non-verbal sounds. The ability to interpret language via lip reading, hand gestures, and context clues is preserved as well. Sometimes, this agnosia is preceded by cortical deafness; however, this is not always the case. Researchers have documented that in most patients exhibiting auditory verbal agnosia, the discrimination of consonants is more difficult than that of vowels, but as with most neurological disorders, there is variation among patients.

Music psychology, or the psychology of music, may be regarded as a branch of both psychology and musicology. It aims to explain and understand musical behaviour and experience, including the processes through which music is perceived, created, responded to, and incorporated into everyday life. Modern music psychology is primarily empirical; its knowledge tends to advance on the basis of interpretations of data collected by systematic observation of and interaction with human participants. Music psychology is a field of research with practical relevance for many areas, including music performance, composition, education, criticism, and therapy, as well as investigations of human attitude, skill, performance, intelligence, creativity, and social behavior.

<span class="mw-page-title-main">Cortical deafness</span> Medical condition

Cortical deafness is a rare form of sensorineural hearing loss caused by damage to the primary auditory cortex. Cortical deafness is an auditory disorder where the patient is unable to hear sounds but has no apparent damage to the structures of the ear. It has been argued to be as the combination of auditory verbal agnosia and auditory agnosia. Patients with cortical deafness cannot hear any sounds, that is, they are not aware of sounds including non-speech, voices, and speech sounds. Although patients appear and feel completely deaf, they can still exhibit some reflex responses such as turning their head towards a loud sound.

Apperceptive agnosia is a failure in recognition that is due to a failure of perception. In contrast, associative agnosia is a type of agnosia where perception occurs but recognition still does not occur. When referring to apperceptive agnosia, visual and object agnosia are most commonly discussed; this occurs because apperceptive agnosia is most likely to present visual impairments. However, in addition to visual apperceptive agnosia there are also cases of apperceptive agnosia in other sensory areas.

Eleanor M. Saffran, an American neuroscientist, was a researcher in the field of Cognitive Neuropsychology. Her interest in Neuropsychology began at the Baltimore City hospitals of Johns Hopkins University, where her research unit focused on neurological patients with language or cognitive impairments. In papers published between 1976 and 1982, Dr. Saffran spelled out the methodological tenets of “cognitive neuropsychology” exemplified in her studies of aphasia, alexia, auditory verbal agnosia, and short-term memory impairment.

Auditory agnosia is a form of agnosia that manifests itself primarily in the inability to recognize or differentiate between sounds. It is not a defect of the ear or "hearing", but rather a neurological inability of the brain to process sound meaning. While auditory agnosia impairs the understanding of sounds, other abilities such as reading, writing, and speaking are not hindered. It is caused by bilateral damage to the anterior superior temporal gyrus, which is part of the auditory pathway responsible for sound recognition, the auditory "what" pathway.

<span class="mw-page-title-main">Isabelle Peretz</span> Canadian psychologist

Isabelle Peretz is a professor of psychology at the University of Montreal, holding a Canada Research Chair and Casavant Chair in neurocognition of music. She specializes in music cognition, focusing on congenital and acquired musical disorders (amusia) and on the cognitive and biological foundations of music processing in general.

Musical memory refers to the ability to remember music-related information, such as melodic content and other progressions of tones or pitches. The differences found between linguistic memory and musical memory have led researchers to theorize that musical memory is encoded differently from language and may constitute an independent part of the phonological loop. The use of this term is problematic, however, since it implies input from a verbal system, whereas music is in principle nonverbal.

<span class="mw-page-title-main">Superior temporal sulcus</span> Part of the brains temporal lobe

In the human brain, the superior temporal sulcus (STS) is the sulcus separating the superior temporal gyrus from the middle temporal gyrus in the temporal lobe of the brain. A sulcus is a deep groove that curves into the largest part of the brain, the cerebrum, and a gyrus is a ridge that curves outward of the cerebrum.

The neuroscience of music is the scientific study of brain-based mechanisms involved in the cognitive processes underlying music. These behaviours include music listening, performing, composing, reading, writing, and ancillary activities. It also is increasingly concerned with the brain basis for musical aesthetics and musical emotion. Scientists working in this field may have training in cognitive neuroscience, neurology, neuroanatomy, psychology, music theory, computer science, and other relevant fields.

Phonagnosia is a type of agnosia, or loss of knowledge, that involves a disturbance in the recognition of familiar voices and the impairment of voice discrimination abilities in which the affected individual does not suffer from comprehension deficits. Phonagnosia is an auditory agnosia, an acquired auditory processing disorder resulting from brain damage, other auditory agnosias include cortical deafness and auditory verbal agnosia also known as pure word deafness.

The Levitin effect is a phenomenon whereby people, even those without musical training, tend to remember songs in the correct key. The finding stands in contrast to the large body of laboratory literature suggesting that such details of perceptual experience are lost during the process of memory encoding, so that people would remember melodies with relative pitch rather than absolute pitch.

Beat deafness is a form of congenital amusia characterized by a person's inability to distinguish musical rhythm or move in time to it.

Musical anhedonia is a neurological condition characterized by an inability to derive pleasure from music. People with this condition, unlike those suffering from music agnosia, can recognize and understand music but fail to enjoy it.

Aniruddh (Ani) D. Patel is a cognitive psychologist known for his research on music cognition and the cognitive neuroscience of music. He is Professor of Psychology at Tufts University, Massachusetts. From a background in evolutionary biology, his work includes empirical research, theoretical studies, brain imaging techniques, and acoustical analysis applied to areas such as cognitive musicology, parallel relationships between music and language, and evolutionary musicology. Patel received a Guggenheim Fellowship in 2018 to support his work on the evolution of musical cognition.

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