N8-acetylspermidine oxidase (propane-1,3-diamine-forming)

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N8-acetylspermidine oxidase (propane-1,3-diamine-forming)
Identifiers
EC no. 1.5.3.15
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N8-acetylspermidine oxidase (propane-1,3-diamine-forming) (EC 1.5.3.15) is an enzyme with systematic name N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming). [1] This enzyme catalyses the following chemical reaction

N8-acetylspermidine + O2 + H2O propane-1,3-diamine + 4-acetamidobutanal + H2O2

This enzyme is also active n N1-acetylspermine, and it has weak activity on N1,N12-diacetylspermine.

Related Research Articles

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<span class="mw-page-title-main">Diamine oxidase</span> Enzyme

Diamine oxidase (DAO), also known "amine oxidase, copper-containing, 1" (AOC1), formerly called histaminase, is an enzyme involved in the metabolism, oxidation, and inactivation of histamine and other polyamines such as putrescine or spermidine in animals. It belongs to the amine oxidase (copper-containing) (AOC) family of amine oxidase enzymes. In humans, DAO is encoded by the AOC1 gene.

Histamine <i>N</i>-methyltransferase Mammalian enzyme involved in the metabolism of histamine

Histamine N-methyltransferase is an enzyme involved in the metabolism of histamine. It is one of two enzymes involved in the metabolism of histamine in mammals, the other being diamine oxidase (DAO). HNMT catalyzes the methylation of histamine in the presence of S-adenosylmethionine (SAM-e) forming N-methylhistamine. The HNMT enzyme is present in most body tissues but is not present in serum. Histamine N-methyltransferase is encoded by a single gene, HNMT, which in humans has been mapped to chromosome 2.

In enzymology, a spermidine dehydrogenase (EC 1.5.99.6) is an enzyme that catalyzes the chemical reaction

In enzymology, a 1,3-propanediol dehydrogenase (EC 1.1.1.202) is an enzyme that catalyzes the chemical reaction

In enzymology, a 3-hydroxyanthranilate oxidase (EC 1.10.3.5) (also called 3-HAO) is an enzyme that catalyzes the chemical reaction:

<span class="mw-page-title-main">Amine oxidase (copper-containing)</span>

Amine oxidase (copper-containing) (AOC) (EC 1.4.3.21 and EC 1.4.3.22; formerly EC 1.4.3.6) is a family of amine oxidase enzymes which includes both primary-amine oxidase and diamine oxidase; these enzymes catalyze the oxidation of a wide range of biogenic amines including many neurotransmitters, histamine and xenobiotic amines. They act as a disulphide-linked homodimer. They catalyse the oxidation of primary amines to aldehydes, with the subsequent release of ammonia and hydrogen peroxide, which requires one copper ion per subunit and topaquinone as cofactor:

The enzyme diaminobutyrate decarboxylase (EC 4.1.1.86) catalyzes the chemical reaction

In enzymology, an acetylspermidine deacetylase (EC 3.5.1.48) is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">Diamine N-acetyltransferase</span>

In enzymology, a diamine N-acetyltransferase is an enzyme that catalyzes the chemical reaction

In enzymology, a homospermidine synthase (spermidine-specific) is an enzyme that catalyzes the chemical reaction

In enzymology, a sym-norspermidine synthase is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">2,6-Diacetylpyridine</span> Chemical compound

2,6-Diacetylpyridine is an organic compound with the formula C5H3N(C(O)CH3)2. It is a white solid that is soluble in organic solvents. It is a disubstituted pyridine. It is a precursor to ligands in coordination chemistry.

Carboxynorspermidine synthase (EC 1.5.1.43, carboxynorspermidine dehydrogenase, carboxyspermidine dehydrogenase, CASDH, CANSDH) is an enzyme with systematic name carboxynorspermidine:NADP+ oxidoreductase. This enzyme catalyses the following chemical reactions

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Polyamine oxidase (propane-1,3-diamine-forming) (EC 1.5.3.14, MPAO, maize PAO) is an enzyme with systematic name spermidine:oxygen oxidoreductase (propane-1,3-diamine-forming). This enzyme catalyses the following chemical reaction

Non-specific polyamine oxidase (EC 1.5.3.17, polyamine oxidase, Fms1, AtPAO3) is an enzyme with systematic name polyamine:oxygen oxidoreductase (3-aminopropanal or 3-acetamidopropanal-forming). This enzyme catalyses the following chemical reaction

MPAO may refer to:

Homospermidine synthase (EC 2.5.1.44) is an enzyme with systematic name putrescine:putrescine 4-aminobutyltransferase (ammonia-forming). This enzyme catalyses the following chemical reaction

Deoxyhypusine synthase (EC 2.5.1.46, spermidine:eIF5A-lysine 4-aminobutyltransferase (propane-1,3-diamine-forming)) is an enzyme with systematic name (eIF5A-precursor)-lysine:spermidine 4-aminobutyltransferase (propane-1,3-diamine-forming). This enzyme catalyses the following chemical reaction

References

  1. Shukla OP, Müller S, Walter RD (March 1992). "Polyamine oxidase from Acanthamoeba culbertsoni specific for N8-acetylspermidine". Molecular and Biochemical Parasitology. 51 (1): 91–8. doi:10.1016/0166-6851(92)90204-w. PMID   1565141.