In human mitochondrial genetics, Haplogroup C is a human mitochondrial DNA (mtDNA) haplogroup.
Apoptosis regulator BAX, also known as bcl-2-like protein 4, is a protein that in humans is encoded by the BAX gene. BAX is a member of the Bcl-2 gene family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis.
In human mitochondrial genetics, haplogroup E is a human mitochondrial DNA (mtDNA) haplogroup typical for the Malay Archipelago. It is a subgroup of haplogroup M9.
In human mitochondrial genetics, Haplogroup Y is a human mitochondrial DNA (mtDNA) haplogroup.
28S ribosomal protein S12, mitochondrial is a protein that in humans is encoded by the MRPS12 gene.
The ATP5MF gene encodes the ATP synthase subunit f, mitochondrial enzyme in humans.
39S ribosomal protein L28, mitochondrial is a protein that in humans is encoded by the MRPL28 gene.
The human gene ATP5PD encodes subunit d of the peripheral stalk part of the enzyme mitochondrial ATP synthase.
39S ribosomal protein L12, mitochondrial is a protein that in humans is encoded by the MRPL12 gene.
Mitochondrial-processing peptidase subunit beta is an enzyme that in humans is encoded by the PMPCB gene. This gene is a member of the peptidase M16 family and encodes a protein with a zinc-binding motif. This protein is located in the mitochondrial matrix and catalyzes the cleavage of the leader peptides of precursor proteins newly imported into the mitochondria, though it only functions as part of a heterodimeric complex.
39S ribosomal protein L1, mitochondrial is a protein that in humans is encoded by the MRPL1 gene.
Tricarboxylate transport protein, mitochondrial, also known as tricarboxylate carrier protein and citrate transport protein (CTP), is a protein that in humans is encoded by the SLC25A1 gene. SLC25A1 belongs to the mitochondrial carrier gene family SLC25. High levels of the tricarboxylate transport protein are found in the liver, pancreas and kidney. Lower or no levels are present in the brain, heart, skeletal muscle, placenta and lung.
39S ribosomal protein L33, mitochondrial is a protein that in humans is encoded by the MRPL33 gene.
39S ribosomal protein L10, mitochondrial is a protein that in humans is encoded by the MRPL10 gene.
Voltage-dependent anion-selective channel protein 2 is a protein that in humans is encoded by the VDAC2 gene on chromosome 10. This protein is a voltage-dependent anion channel and shares high structural homology with the other VDAC isoforms. VDACs are generally involved in the regulation of cell metabolism, mitochondrial apoptosis, and spermatogenesis. Additionally, VDAC2 participates in cardiac contractions and pulmonary circulation, which implicate it in cardiopulmonary diseases. VDAC2 also mediates immune response to infectious bursal disease (IBD).
Carterocephalus silvicola, the northern chequered skipper, is a species of butterfly of the family Hesperiidae. It is found in northern Europe and the northern and eastern Palearctic.
Histia is a genus of moths of the family Zygaenidae.
Chrysophanol, also known as chrysophanic acid, is a fungal isolate and a natural anthraquinone. It is a C-3 methyl substituted chrysazin of the trihydroxyanthraquinone family.
Reductive stress is the counterpart to oxidative stress, where electron acceptors are expected to be mostly reduced. It can be caused by excess amounts of glutathione, and can contribute to cytotoxicity. Although different organelles may each have a different redox status, through probing for factors such as glutathione and hydrogen peroxide (H2O2), it was determined that reductive stress is present in the endoplasmic reticulum (ER) of senescent cells. Reductive stress is significant in the aging process of a cell and when ER oxidation status is elevated, cellular aging is slowed. In particular, when reductive stress is increased, it may result in many downstream effects such as increased apoptosis, decreased cell survival, and mitochondrial dysfunction—all of which need to be properly regulated to ensure that the needs of the cell are met. Reductive stress has even been suggested to lead to higher probability of cardiomyopathy in humans. This has also been mysteriously linked to the abundant presence of heat shock protein 27 (Hsp27), suggesting that high levels of Hsp27 induce can induce cardiomyopathy. Reductive stress is present in many diseases with abnormalities such as the increase of reducing equivalents, resulting in issues such as hypoxia-induced oxidative stress.
Vitis pseudoreticulata, commonly known as the wild Chinese grape or eastern Chinese grape, is a Chinese liana in the grape family. It is native to eastern China, specifically the provinces of Anhui, Fujian, Guangdong, Guangxi, Henan, Hubei, Hunan, Jiangsu, Jiangxi, and Zhejiang. The plant grows at altitudes of 100–300 m (330–980 ft) and bears medium-sized purplish-black grapes. It has been observed to be resistant to damage from moisture, white rot, anthracnose, and Downy mildew.
