Pandoraea | |
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Scientific classification | |
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Genus: | Pandoraea Coenye et al. 2000 [1] |
Type species | |
Pandoraea apista [2] | |
Species | |
Pandoraea apista |
Pandoraea is a genus of Gram-negative, non-spore-forming, motile bacteria with a single polar flagellum, of the family Burkholderiaceae and class Betaproteobacteria. [3] [4]
Pandoraea spp. are increasingly reported as opportunistic pathogens in patients with cystic fibrosis, immunocompromised hosts, and critically ill individuals. These bacteria display intrinsic multidrug resistance, with frequent resistance to β-lactams, aminoglycosides, fluoroquinolones and polymyxins. Imipenem and trimethoprim-sulfamethoxazole are the agents that most often retain activity, although clinical data remain limited and standardized susceptibility breakpoints are lacking. [5]