| Phoneutria keyserlingi | |
|---|---|
Scientific classification  | |
| Kingdom: | Animalia |
| Phylum: | Arthropoda |
| Subphylum: | Chelicerata |
| Class: | Arachnida |
| Order: | Araneae |
| Infraorder: | Araneomorphae |
| Family: | Ctenidae |
| Genus: | Phoneutria |
| Species: | P. keyserlingi |
| Binomial name | |
| Phoneutria keyserlingi (F.O. P-Cambridge, 1897) [1] | |
Phoneutria keyserlingi is a species of spiders in the family Ctenidae, found in Brazil. [1]
P. keyserlingi is venomous and should be treated with caution, studies on the other Phoneutria are scarce, however, a recent characterization of the venom of this species has shown that it contains neurotoxins similar to those isolated from Phoneutria nigriventer and that are active on the neuronal ion (Ca2+, Na+ and K+) channels and NMDA-type glutamate receptors. [2] CRISP-1 is a protein (basically an allergen) from the cysteine-rich P. keyserlingi venom, proteins in the CAP domain that includes CRISP have also been recruited from cephalopods , cone snails , scorpions , reptiles and ticks , the proteins in the domain CAP are allergy-inducing toxins, although their role in spider toxins has yet to be determined, CRISP-1 is known to induce a dangerous allergic reaction in humans. [3] [4]