Language isolates are languages that cannot be classified into larger language families with any other languages. Korean and Basque are two of the most commonly cited language isolates, but there are many others such as Ainu in Asia, Sandawe in Africa, and Haida in the Americas. "The absolute number of language isolates, is, however, uncertain and in fact will never be known."
Over a thousand indigenous languages are spoken by the Indigenous peoples of the Americas. These languages cannot all be demonstrated to be related to each other and are classified into a hundred or so language families, as well as a number of extinct languages that are unclassified due to a lack of data.
The Pima are a group of Native Americans living in an area consisting of what is now central and southern Arizona, as well as northwestern Mexico in the states of Sonora and Chihuahua. The majority population of the two current bands of the Akimel O'odham in the United States are based in two reservations: the Keli Akimel Oʼotham on the Gila River Indian Community (GRIC) and the On'k Akimel O'odham on the Salt River Pima-Maricopa Indian Community (SRPMIC).
Uto-Aztecan, Uto-Aztekan or (rarely) Uto-Nahuatl is a family of indigenous languages of the Americas, consisting of over thirty languages. Uto-Aztecan languages are found almost entirely in the Western United States and Mexico. The name of the language family was created to show that it includes both the Ute language of Utah and the Nahuan languages of Mexico.
Muskogean is a Native American language family spoken in different areas of the Southeastern United States. Though the debate concerning their interrelationships is ongoing, the Muskogean languages are generally divided into two branches, Eastern Muskogean and Western Muskogean. Typologically, Muskogean languages are agglutinative. One documented language, Apalachee, is extinct and the remaining languages are critically endangered.
Zuni is a language of the Zuni people, indigenous to western New Mexico and eastern Arizona in the United States. It is spoken by around 9,500 people, especially in the vicinity of Zuni Pueblo, New Mexico, and much smaller numbers in parts of Arizona.
Comecrudan refers to a group of possibly related languages spoken in the southernmost part of Texas and in northern Mexico along the Rio Grande of which Comecrudo is the best known. Very little is known about these languages or the people who spoke them. Knowledge of them primarily consists of word lists collected by European missionaries and explorers. All Comecrudan languages are extinct.
Yokuts, formerly known as Mariposa, is an endangered language spoken in the interior of Northern and Central California in and around the San Joaquin Valley by the Yokuts people. The speakers of Yokuts were severely affected by disease, missionaries, and the Gold Rush. While descendants of Yokuts speakers currently number in the thousands, most of the constituent dialects are now extinct.
Plateau Penutian is a family of languages spoken in northern California, reaching through central-western Oregon to northern Washington and central-northern Idaho.
Kalapuyan is a small extinct language family that was spoken in the Willamette Valley of Western Oregon, United States. It consists of three languages.
The Tepehuán are an indigenous people of Mexico. They live in Northwestern, Western, and some parts of North-Central Mexico. The indigenous Tepehuán language has three branches: Northern Tepehuan, Southeastern Tepehuan, Southwestern Tepehuan. The heart of the Tepehuan territory is in the Valley of Guadiana in Durango, but they eventually expanded into southern Chihuahua, eastern Sinaloa, and northern Jalisco, Nayarit, and Zacatecas. By the time of the Spanish conquest of Mexico, Tepehuan lands spanned a large territory along the Sierra Madre Occidental. Tepehuán groups are divided into the Ódami, Audam, and O'dam, each with their own language, culture, and beliefs.
Lyle Richard Campbell is an American scholar and linguist known for his studies of indigenous American languages, especially those of Central America, and on historical linguistics in general. Campbell is professor emeritus of linguistics at the University of Hawaii at Manoa.
The Waorani (Huaorani) language, commonly known as Sabela is a vulnerable language isolate spoken by the Huaorani people, an indigenous group living in the Amazon rainforest between the Napo and Curaray Rivers in Ecuador. A small number of speakers with so-called uncontacted groups may live in Peru.
Guajiboan is a language family spoken in the Orinoco River region in eastern Colombia and southwestern Venezuela, a savanna region known as the Llanos.
Jicaquean, also known as Tolan, is a small language family of Honduras. There are two attested Jicaquean languages, Tol and Western Jicaque, which Campbell (1997) reports were about as distant as English and Swedish. Only Tol survives.
Tepehuán (Tepehuano) is the name of three closely related languages of the Piman branch of the Uto-Aztecan language family, all spoken in northern Mexico. The language is called O'otham by its speakers.
Pima Bajo is a Mexican indigenous language of the Piman branch of the Uto-Aztecan language family, spoken by around 1,000 speakers in northern Mexico. The language is called O'ob No'ok by its speakers. The closest related languages are O'odham and the O'othams.
Quechumaran or Kechumaran is a language-family proposal that unites Quechua and Aymara. Quechuan languages, especially those of the south, share a large amount of vocabulary with Aymara. Terrence Kaufman finds the proposal reasonably convincing, but Willem Adelaar, a Quechua specialist, believes the similarities to be caused by borrowing during long-term contact. Lyle Campbell suspects that the proposal is valid but does not consider it to have been conclusively proved.
The Tepecano language is an extinct indigenous language of Mexico belonging to the Uto-Aztecan language-family. It was formerly spoken by a small group of people in Azqueltán, Jalisco, a small village on the Río Bolaños in the far northern part of the state, just east of the territory of the Huichol people. Most closely related to Southern Tepehuán of the state of Durango, Tepecano was a Mesoamerican language and evinced many of the traits that define the Mesoamerican Linguistic Area. So far as is known, the last speaker of Tepecano was Lino de la Rosa, who was still living as of February 1980.