Cayey, officially Cayey de Muesas, is a mountain town and municipality in central Puerto Rico located on the Sierra de Cayey within the Central Mountain range, north of Salinas and Guayama; south of Cidra and Caguas; east of Aibonito and Salinas; and west of San Lorenzo. Cayey is spread over 21 barrios plus Cayey Pueblo. It is part of the San Juan-Caguas-Guaynabo Metropolitan Statistical Area.
Puerto Rico Highway 52 (PR-52), a major toll road in Puerto Rico, is also known as Autopista Luis A. Ferré. It was formerly called Expreso Las Américas. It runs from PR-1 in southwest Río Piedras and heads south until it intersects with highway PR-2 in Ponce. At its north end, the short PR-18 continues north from PR-52 towards San Juan. This short segment is known as Expreso Las Américas, the only segment of the route still unofficially bearing this name, since PR-18 is officially named Roberto Sánchez Vilella Expressway. The combined route of PR-18 and PR-52 runs concurrent with the unsigned Interstate Highway PRI-1. Toll stations are located in San Juan, Caguas, Salinas, Juana Díaz, and Ponce.
This is a list of properties and historic districts that are listed on the National Register of Historic Places (NRHP) in Puerto Rico, not to be confused with the Puerto Rico Register of Historic Sites and Zones. There are more than 375 listings in Puerto Rico, with one or more listing in each of Puerto Rico's 78 municipalities.
Puerto Rico Highway 2 (PR-2) is a road in Puerto Rico that connects the cities of San Juan and Ponce. At 156 miles (230 km) long, it is Puerto Rico's longest singled-signed highway.
Puerto Rico Highway 3(PR-3) at nearly 100 miles long, is the second-longest highway on Puerto Rico. It connects the San Juan neighborhood of Río Piedras to downtown Salinas indirectly around the eastern coast of the island. Highway 3 ranges from a three lane urban avenue in San Juan to a one lane rural road past Fajardo. While other roads connect San Juan, it runs the coastline of Puerto Rico east of San Juan, beginning in Río Piedras near Santurce and goes to Fajardo where it goes south paralleling the coastline to Humacao and Maunabo. It goes up to a mountain-scenic route and goes west to Salinas, where it meets PR-1.
Puerto Rico Highway 53 (PR-53) or unsigned Interstate PR3 is a main tollway that is parallel to Puerto Rico Highway 3, which goes from Fajardo to Salinas. Some segments are still in planning, but when finished it will be about 58 miles (93 km) in length. Two tunnels, about 0.6 mi (1 km) long each, in the towns of Yabucoa and Maunabo were completed in October 2008. It will connect the cities of Fajardo, Ceiba, Naguabo, Humacao, Yabucoa, Maunabo, Patillas, Arroyo, Guayama and Salinas, thus bordering the entire eastern and southeastern coasts of Puerto Rico. Its northern terminus is at PR-3 and PR-194 in Fajardo, and its south terminus is at PR-52 in Salinas.
Puerto Rico Highway 10 (PR-10) is a major highway in Puerto Rico. The primary state road connects the city of Ponce in the south coast to Arecibo in the north; it is also the shortest route between the two cities.
Puerto Rico Highway 181 (PR-181), also known as Expreso Trujillo Alto, is a road in Puerto Rico connecting the municipality of San Juan on the northeastern coastal plain with Patillas on the southeastern coastal plain. Beginning in the Rio Piedras district of barrio Oriente in San Juan at Jesus de Piñero Avenue (PR-17), it runs through Trujillo Alto, Gurabo and San Lorenzo on the Caguas Valley, and western Yabucoa and eastern Patillas on the Sierra de Cayey, before ending in the Patillas Pueblo downtown area on the southeastern coastal plain of Puerto Rico. PR-181 is a four-lane highway from San Juan through the Trujillo Alto Pueblo downtown area, and completely rural on the way to Patillas with the exception of a small tract in Gurabo where it intersects PR-30. Along with PR-10, PR-149, PR-1 and PR-52, it is one of the longest roads crossing the main island from north to south.
Puerto Rico Highway 12 (PR-12), also called Avenida Malecón, and Avenida Santiago de los Caballeros, is a 6.4-kilometer, limited-access highway entirely located within the city limits of Ponce, Puerto Rico, and connecting Puerto Rico Highway 14 to the La Guancha area in Barrio Playa in Ponce. It is similar to a freeway but has one traffic light near its intersection with PR-14. In addition to its northern and southern terminus, the highway has four full interchange exits: PR-52, PR-2, PR-133/Calle Comercio, and Avenida Las Américas. Since PR-12's southern terminus is at the Port of Ponce, its traffic volume is expected to grow as construction in the new Port of the Americas is completed.
Puerto Rico Highway 184 (PR-184) is a main, rural highway that connects Patillas to Cayey, Puerto Rico, with plans to be extended to Cidra. It extends from PR-3 in Cacao Bajo to PR-1 in Beatriz.
The San Juan–Bayamón–Caguas metropolitan area, most commonly known as the San Juan metropolitan area, is the largest and most populous metropolitan statistical area (MSA) in Puerto Rico, concentrated in the capital municipality of San Juan and surrounding municipalities, including Bayamón, Caguas, and Carolina, on the northeastern coastal plain of the main island. One of 6 metropolitan statistical areas in Puerto Rico, it lies within the San Juan–Bayamón combined statistical area (CSA), which is one of 3 primary statistical areas in the main island as defined by the United States Census Bureau. As of 2023, census estimates place the population of the San Juan–Bayamón–Caguas metropolitan area at 2,035,733.
The Ruta Panorámica, officially the Ruta Panorámica Luis Muñoz Marín, is a 167-mile (269 km) network of some 40 secondary roads which traverse the island of Puerto Rico from west to east along its Cordillera Central. Most of the route consists of three roads, PR-105, PR-143, and PR-182. The route starts in Mayagüez and ends in Maunabo. The first major segment of the route runs from Mayagüez to Maricao as Route 105, then from Adjuntas to Aibonito as Route 143, and then follows Route 182 toward Maunabo.
The Arenas Bridge is a truss bridge built in 1894 between the municipalities of Cayey and Cidra in Puerto Rico. Also known as Puente Rio La Plata, it was the longest bridge constructed in Puerto Rico during the Spanish colonial period. It crosses the Rio de la Plata, the longest river in Puerto Rico. According to the U.S. National Park Service, "[t]his is the most important metal bridge in Puerto Rico from the period." The bridge is still standing.
The Carretera Central is a historic north–south central highway in Puerto Rico, linking the cities of San Juan and Ponce by way of Río Piedras, Caguas, Cayey, Aibonito, Coamo, and Juana Díaz. It crosses the Cordillera Central. Plans for the road started in the first half of the 19th century, and the road was fully completed in 1898. At the time the United States took possession of Puerto Rico in 1898, the Americans called it "the finest road in the Western Hemisphere."
This portion of National Register of Historic Places listings in Puerto Rico is along the central mountain region, from Las Marías and Maricao in the central-west to Juncos in the central-east, including the slopes of the Cordillera.
Puerto Rico Highway 506 (PR-506) is a two-lane tertiary highway in the municipality of Ponce in Puerto Rico. The road runs north to south, joining PR-14, where PR-506 starts, to PR-52 interchange, where it ends. The road is located entirely within Barrio Coto Laurel and its length is 2.0 km (1.2 mi).
Porta Cordillera, or simply Central Region, is a land-locked tourism region located in the central mountainous area of Puerto Rico. Porta Cordillera was officially launched in July 2012 by the Puerto Rico Tourism Company. It consists of 16 municipalities: Aguas Buenas, Cidra, Cayey, Comerío, Aibonito, Naranjito, Barranquitas, Corozal, Orocovis, Morovis, Ciales, Jayuya, Florida, Utuado, Adjuntas and Lares.
Puerto Rico has approximately 14,400 kilometers (8,900 mi) of national, forest and municipal roads. The highways serve the more than 3 million residents, and 3-4 million tourists who visit each year.
PR-123 in Primero–Segundo 
