Rauvolfia micrantha | |
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Scientific classification | |
Kingdom: | Plantae |
Clade: | Tracheophytes |
Clade: | Angiosperms |
Clade: | Eudicots |
Clade: | Asterids |
Order: | Gentianales |
Family: | Apocynaceae |
Genus: | Rauvolfia |
Species: | R. micrantha |
Binomial name | |
Rauvolfia micrantha | |
Rauvolfia micrantha, the small-flowered snakeroot, [1] is a plant that is indigenous to southwestern India, southern Thailand, and Vietnam. It has a woody, shrub-like appearance and attractive flowers.
The general habitat of plants in the genus Rauvolfia is semi-evergreen and evergreen forest distributed along tropical areas of Asia, Africa, and America. The plant is endemic to the evergreen forest of the Tinnevelly and Travancore hills in the Indian Western Ghats (states of Kerala and Tamil Nadu. [2] It flowers and fruits between March and October. [3]
Rauvolfia micrantha is a critically endangered plant. The species has scanty distribution in the wild due to habitat degradation, fragmentation of population and narrow environmental niche. [3] Efforts toward its conservation involve cryopreservation of seeds and in-vitro methods. [4] Organogenesisis the standardized protocol for regeneration of R. micrantha in culture. Nodes of the plant are used as explants. [5] Cryopreservation of the seeds has proven to be slightly difficult. The seeds of R. micrantha are of intermediate type and hence require strict conditions during this process. [5]
The plant is a perennial woody shrub that grows at elevations up to about 600 m (2,000 ft). Branches are slender and glabrous (having no trichomes or "hair"). The leaves are approximately 8–13 cm (3–5 in) x 2–5 cm (0.8–2 in), elliptic, membranous, abruptly acuminate at both ends; petiole 1 cm long. [6] [7] Flowers are arranged in axillary long-peduncled congested cymes; sepals are 1.5 mm (0.059 in) long, triangular, acute and basely connate. The corolla is colored white with reddish color at throat, and is about 8 mm (0.31 in) long, glabrous, with acute ovate lobes. Capsule is 7 mm (0.28 in) x 5 mm (0.20 in), ovoid acute, and glabrous. [6] Fruits are obliquely ovate and pointed.
Rauvolfia micrantha is related to the snakeroot plant (Rauvolfia serpentina) which is used as a traditional herbal medicine. However, isoenzyme analysis reveals that it is more closely related to Rauvolfia tetraphylla L. [8]
Flowering reaches its peak in the month of May and anthesis occurs between 5:00 am and 8:30 am with a peak at 7:00 am. Dehiscence occurs between 6:00 am and 10:30 am on the day of the anthesis. The stigmas are receptive the day before anthesis, however, become increasingly receptive on the day of anthesis. [3] The major insect pollinators included Apis florea (honeybee), Oecophylla smargadina (red ant), Tetragonula iridipennis (pollen bee) and butterflies such as Pachliopta aristolochaea , Pachliopta hector , Delias eucharis and Euploea core . [3]
Hairy root induction of the plant is achieved in culture by using infection with Agrobacterium rhizogenes strains. [9]
Other nutrients and chemicals in the plant include phenolics, flavonoids, vitamins and carotenoids. The extracts also had antioxidant properties in vitro . [12]
The plant is used as a substitute for R. serpentina in Ayurvedic practices in Kerala, India for nervous disorders such as insomnia and insanity.[ citation needed ]
Apocynaceae is a family of flowering plants that includes trees, shrubs, herbs, stem succulents, and vines, commonly known as the dogbane family, because some taxa were used as dog poison. Members of the family are native to the European, Asian, African, Australian, and American tropics or subtropics, with some temperate members. The former family Asclepiadaceae is considered a subfamily of Apocynaceae and contains 348 genera. A list of Apocynaceae genera may be found here.
Reserpine is a drug that is used for the treatment of high blood pressure, usually in combination with a thiazide diuretic or vasodilator. Large clinical trials have shown that combined treatment with reserpine plus a thiazide diuretic reduces mortality of people with hypertension. Although the use of reserpine as a solo drug has declined since it was first approved by the FDA in 1955, the combined use of reserpine and a thiazide diuretic or vasodilator is still recommended in patients who do not achieve adequate lowering of blood pressure with first-line drug treatment alone. The reserpine-hydrochlorothiazide combo pill was the 17th most commonly prescribed of the 43 combination antihypertensive pills available In 2012.
Rauvolfia is a genus of evergreen trees and shrubs, commonly known as devil peppers, in the family Apocynaceae. The genus is named to honor Leonhard Rauwolf. The genus can mainly be found in tropical regions of Africa, Asia, Latin America, and various oceanic islands.
Rauvolfia serpentina, the Indian snakeroot, devil pepper, or serpentine wood, is a species of flower in the milkweed family Apocynaceae. It is native to the Indian subcontinent and East Asia.
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Nepenthes khasiana is an endangered tropical pitcher plant of the genus Nepenthes. It is the only Nepenthes species native to India. It is thought to attract prey by means of blue fluorescence.
Salimuzzaman Siddiqui, was a Pakistani organic chemist specialising in natural products, and a professor of chemistry at the University of Karachi.
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Strictosidine synthase (EC 4.3.3.2) is an enzyme in alkaloid biosynthesis that catalyses the condensation of tryptamine with secologanin to form strictosidine in a formal Pictet–Spengler reaction:
Hairy root culture, also called transformed root culture, is a type of plant tissue culture that is used to study plant metabolic processes or to produce valuable secondary metabolites or recombinant proteins, often with plant genetic engineering.
Senna occidentalis, commonly known as coffee senna, styptic weed, or septicweed, is a species of flowering plant in the family Fabaceae and is native to the southern United States of America, Mexico and South America. It is a shrub with pinnate leaves, with three to seven pairs of broadly elliptic to egg-shaped leaflets, and yellow flowers arranged in groups of two to four, with six fertile stamens in each flower. It is an aggressive, pantropical weed.
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Senna italica, the Port Royal senna, Italian senna, or Senegal senna is a legume tree in the genus Senna. It is recognized by many other common names based on the regions it grows in. In India, it is used to produce a powder for treating hair-related diseases which is known as “neutral henna”. Whereas, in some parts of the world, this species is cultivated for the leaves which yield the drug senna, known commonly as Senna glycoside, which in turn is the base for a laxative. Senegal senna is easily distinguishable through its many distinctive features. There are 3 subspecies of this plant based on the size of the inflorescence and the length of the petiole. The subspecies are italica, micrantha, and arachoides. In many regions, this plant is cultivated commercially and medicinally.
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