Smitilbin

Last updated
Smitilbin
Smitilbin.svg
Names
IUPAC name
(2R,3S)-2-(3,5-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-2,3-dihydrochromen-4-one
Other names
Isoastilbin B
Identifiers
3D model (JSmol)
ChemSpider
PubChem CID
Properties
C21H22O11
Molar mass 450.39 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Smitilbin is a flavanonol, a type of flavonoid. It is a rhamnoside that can be isolated in Smilax glabra [2] (Chinaroot, sarsaparilla).

Flavanonol class of chemical compounds

The flavanonols are a class of flavonoids that use the 3-hydroxy-2,3-dihydro-2-phenylchromen-4-one backbone.

Smilax glabra, the Chinaroot, tufuling (土茯苓) or sarsaparilla, is a plant species in the genus Smilax. It is native to China, the Himalayas, and Indochina.

Contents

Uses

Smitilbin could be used for preventing immunological hepatocyte damage. [3]

In biology, immunity is the balanced state of multicellular organisms having adequate biological defenses to fight infection, disease, or other unwanted biological invasion, while having adequate tolerance to avoid allergy, and autoimmune diseases.

Hepatocyte cell type

A hepatocyte is a cell of the main parenchymal tissue of the liver. Hepatocytes make up 70-85% of the liver's mass. These cells are involved in:

Neosmitilbin Neosmitilbin.svg
Neosmitilbin

Neosmitilbin is a stereoisomer of smitilbin.


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Baicalein chemical compound

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Tetrandrine chemical compound

Tetrandrine, a bis-benzylisoquinoline alkaloid, is a calcium channel blocker. It has anti-inflammatory, immunologic and antiallergenic effects. It inhibits the degranulation of mast cells. It has a "quinidine-like" anti-arrhythmic effect. It has been isolated from Stephania tetrandra S Moore, and other Chinese and Japanese herbs. It has vasodilatory properties and can therefore reduce blood pressure. Tetrandrine may have potential use for the treatment of liver disease and liver cancer. Tetrandrine has potential therapeutic value to prevent excess scarring/fibrosis in conjunctiva following trabeculectomy or in patients with severe conjunctival inflammation. Tetrandrine has anti-inflammatory and anti-fibrogenic actions, which make tetrandrine and related compounds potentially useful in the treatment of lung silicosis, liver cirrhosis, and rheumatoid arthritis. Tetrandrine has also been shown to inhibit entry of Ebola virus into host cells in vitro and showed therapeutic efficacy against Ebola in preliminary studies on mice.

Taxifolin chemical compound

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Astilbin chemical compound

Astilbin is a flavanonol, a type of flavonoid. Astilbin is the (2R-trans)-isomer; neoisoastilbin is the (2S-cis)-isomer and isoastilbin is the (2R-cis)-isomer.

Licochalcone A chemical compound

Licochalcone A is a chalconoid, a type of natural phenol. It can be isolated from root of Glycyrrhiza glabra (liquorice) or Glycyrrhiza inflata. It shows antimalarial, anticancer, antibacterial and antiviral properties in vitro.

Kaempferol 7-<i>O</i>-glucoside chemical compound

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<i>Smilax china</i> species of plant

Smilax china is a climbing plant species in the genus Smilax. It is native to China, Korea, Taiwan, Japan, Philippines, Vietnam, Thailand, Myanmar, and Assam. Common names for the plant include China root.

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References