Stefan Kutzsche

Last updated
Stefan Kutzsche
Born15 April 1954
Alma mater
Scientific career
Fields Medicine (pediatrics, neonatology, anesthesiology, medical ethics, education)
Institutions
Thesis Effects of hypoxemia and reoxygenation on cerebral microcirculation, nitric oxide, hydrogen peroxide and excitatory amino acid concentrations  (2002)
Doctoral advisor Ola Didrik Saugstad

Stefan Kutzsche (born 15 April 1954) [1] [2] is a Norwegian paediatrician, neonatologist and anaesthesiologist. His research fields include neonatology and neuroscience, medical ethics, education, and the history of medicine.

Contents

Background and career

He was born in Frankfurt to Norwegian and German parents, the grandson of the mathematician Theodor Haagaas. He graduated as a medical doctor at the University of Hamburg in 1983 and obtained a PhD (dr.med.) degree in neonatology from the University of Oslo in 2002. [3] [4] [5] He is double board certified in paediatrics [6] and anaesthesiology. [7] He also holds an MHA in health administration and health economics from the University of Oslo (2006), [8] an MSc in health professions education from the University of Maastricht (2011), [9] and a certificate in paediatric bioethics from the Children's Mercy Bioethics Centre in Kansas City, MO (2013). [10]

He was a resident at Vestfold Hospital, Akershus University Hospital, and Oslo University Hospital, Ullevål (1985–1991). From 1994 to 2005 he was a senior consultant paediatric anaesthesiologist at Ullevål. He was an assistant professor at the Institute of Clinical Medicine at the University of Tromsø (1993) and a research fellow at the Pediatric Research Institute/the Institute for Surgical Research at the University of Oslo/The National Hospital (1994–1998). [5] From 2000 to 2005 he was a senior consultant in paediatric intensive care medicine at Ullevål, heading the department 2001–2002. From 2005 to 2014 he was a senior consultant neonatologist at Ullevål. [11] [12] He also served with No. 330 Squadron of the Royal Norwegian Air Force in Banak on search and rescue (SAR) and air ambulance missions in northernmost Norway and the waters of the High North 1993–2005. [13] He was chief physician at the Norwegian Air Ambulance Foundation 2008–2009. [1] From 2014 to 2018 he was an associate professor at the International Medical University (IMU) in Kuala Lumpur, [14] [4] and from 2016 to 2018 the director of the IMU Centre for Education. [15] He has also taken part in voluntary work for the Angkor Hospital for Children in Cambodia. [16] In 2019 he became a special advisor at Oslo University Hospital. [17]

He has been a member and chairman of the Board for Licensing Matters and Foreign Medical Practitioners in Norway (1998–2007), [18] a board member of the Norwegian Society of Pediatricians and editor of its journal Paidos (2009–2014), [19] a member of the Norwegian specialty committee for pediatrics, [20] and a member of the clinical ethics committee at Oslo University Hospital (2012–2014). [21] He is an advisory member of the IMU Centre for Bioethics and Humanities. [22] He is a member of the editorial committee of Acta Paediatrica . [23]

Research

He has published in the fields of neonatology and neuroscience, medical ethics, medical education, and the history of medicine. [22] [24] [1] [9] [10] In particular, he has collaborated with Ola Didrik Saugstad in research on secondary brain injury in newborn infants as a result of perinatal asphyxia and resuscitation with 100% oxygen or normal air. [25] [5] This research, which he and other members of Saugstad's research group conducted, contributed to the amendment of international guidelines for newborn resuscitation in 2010. [26] He has published papers in Pediatrics , Pediatric Research , Biology of the Neonate , Critical Care Medicine , Pediatric Critical Care Medicine , Thrombosis Research , Acta Paediatrica , Acta Anaesthesiologica Scandinavica , and other journals.

Selected publications

Related Research Articles

<span class="mw-page-title-main">Asphyxia</span> Severely deficient supply of oxygen

Asphyxia or asphyxiation is a condition of deficient supply of oxygen to the body which arises from abnormal breathing. Asphyxia causes generalized hypoxia, which affects all the tissues and organs, some more rapidly than others. There are many circumstances that can induce asphyxia, all of which are characterized by the inability of a person to acquire sufficient oxygen through breathing for an extended period of time. Asphyxia can cause coma or death.

<span class="mw-page-title-main">Apgar score</span> Scale for newborn viability

The Apgar score is a quick way for health professionals to evaluate the health of all newborns at 1 and 5 minutes after birth and in response to resuscitation. It was originally developed in 1952 by an anesthesiologist at Columbia University, Virginia Apgar, to address the need for a standardized way to evaluate infants shortly after birth.

<span class="mw-page-title-main">Infant respiratory distress syndrome</span> Human disease affecting newborns

Infant respiratory distress syndrome (IRDS), also called respiratory distress syndrome of newborn, or increasingly surfactant deficiency disorder (SDD), and previously called hyaline membrane disease (HMD), is a syndrome in premature infants caused by developmental insufficiency of pulmonary surfactant production and structural immaturity in the lungs. It can also be a consequence of neonatal infection and can result from a genetic problem with the production of surfactant-associated proteins.

<span class="mw-page-title-main">Kangaroo care</span> Technique of newborn care

Kangaroo mother care (KMC), which involves skin-to-skin contact (SSC), is an intervention to care for premature or low birth weight (LBW) infants. The technique and intervention is the recommended evidence-based care for LBW infants by the World Health Organization (WHO) since 2003.

Perinatal asphyxia is the medical condition resulting from deprivation of oxygen to a newborn infant that lasts long enough during the birth process to cause physical harm, usually to the brain. It remains a serious condition which causes significant mortality and morbidity. It is also the inability to establish and sustain adequate or spontaneous respiration upon delivery of the newborn, an emergency condition that requires adequate and quick resuscitation measures. Perinatal asphyxia is also an oxygen deficit from the 28th week of gestation to the first seven days following delivery. It is also an insult to the fetus or newborn due to lack of oxygen or lack of perfusion to various organs and may be associated with a lack of ventilation. In accordance with WHO, perinatal asphyxia is characterised by: profound metabolic acidosis, with a pH less than 7.20 on umbilical cord arterial blood sample, persistence of an Apgar score of 3 at the 5th minute, clinical neurologic sequelae in the immediate neonatal period, or evidence of multiorgan system dysfunction in the immediate neonatal period. Hypoxic damage can occur to most of the infant's organs, but brain damage is of most concern and perhaps the least likely to quickly or completely heal. In more pronounced cases, an infant will survive, but with damage to the brain manifested as either mental, such as developmental delay or intellectual disability, or physical, such as spasticity.

<span class="mw-page-title-main">Cerebral hypoxia</span> Oxygen shortage of the brain

Cerebral hypoxia is a form of hypoxia, specifically involving the brain; when the brain is completely deprived of oxygen, it is called cerebral anoxia. There are four categories of cerebral hypoxia; they are, in order of increasing severity: diffuse cerebral hypoxia (DCH), focal cerebral ischemia, cerebral infarction, and global cerebral ischemia. Prolonged hypoxia induces neuronal cell death via apoptosis, resulting in a hypoxic brain injury.

<span class="mw-page-title-main">Ernst Moro</span>

Ernst Moro was an Austrian physician and pediatrician who was the first in western medicine to describe the infant reflex that was named after him.

<span class="mw-page-title-main">Intrauterine hypoxia</span> Medical condition when the fetus is deprived of sufficient oxygen

Intrauterine hypoxia occurs when the fetus is deprived of an adequate supply of oxygen. It may be due to a variety of reasons such as prolapse or occlusion of the umbilical cord, placental infarction, maternal diabetes and maternal smoking. Intrauterine growth restriction may cause or be the result of hypoxia. Intrauterine hypoxia can cause cellular damage that occurs within the central nervous system. This results in an increased mortality rate, including an increased risk of sudden infant death syndrome (SIDS). Oxygen deprivation in the fetus and neonate have been implicated as either a primary or as a contributing risk factor in numerous neurological and neuropsychiatric disorders such as epilepsy, attention deficit hyperactivity disorder, eating disorders and cerebral palsy.

<span class="mw-page-title-main">Umbilical line</span>

An umbilical line is a catheter that is inserted into one of the two arteries or the vein of the umbilical cord. Generally the UAC/UVC is used in Neonatal Intensive Care Units (NICU) as it provides quick access to the central circulation of premature infants. UAC/UVC lines can be placed at the time of birth and allow medical staff to quickly infuse fluids, inotropic drugs, and blood if required. It is sometimes used in term or near-term newborns in whom the umbilical cord stump is still connected to the circulatory system. Medications, fluids, and blood can be given through this catheter and it allows monitoring of blood gasses and withdrawing of blood samples. Transumbilical catheter intervention is also a method of gaining access to the heart, for example to surgically correct a patent ductus arteriosus.

Ola Didrik Saugstad is a Norwegian pediatrician, neonatologist and neuroscientist noted for his research on resuscitation of newborn children and his contribution to reduce child mortality. He is a Research Professor at Oslo University Hospital and Professor of Neonatology at Northwestern University's Feinberg School of Medicine in Chicago. He is Professor Emeritus of Pediatrics at the University of Oslo and was Director of the Department of Pediatric Research at Oslo University Hospital from 1991 to 2017.

Acta Paediatrica is a monthly peer-reviewed medical journal covering paediatrics. It is published by Wiley-Blackwell on behalf of the Foundation Acta Paediatrica, based at the Karolinska Institute in Sweden.

Kåre Ingmar Berg, MD was a Norwegian professor in medical genetics, physician-in-chief and well-cited researcher.

Mild total body hypothermia, induced by cooling a baby to 33-34°C for three days after birth, is nowadays a standardized treatment after moderate to severe hypoxic ischemic encephalopathy in full-term and near to fullterm neonates. It has recently been proven to be the only medical intervention which reduces brain damage, and improves an infant's chance of survival and reduced disability.

Neonatal sepsis is a type of neonatal infection and specifically refers to the presence in a newborn baby of a bacterial blood stream infection (BSI) in the setting of fever. Older textbooks may refer to neonatal sepsis as "sepsis neonatorum". Criteria with regards to hemodynamic compromise or respiratory failure are not useful clinically because these symptoms often do not arise in neonates until death is imminent and unpreventable. Neonatal sepsis is divided into two categories: early-onset sepsis (EOS) and late-onset sepsis (LOS). EOS refers to sepsis presenting in the first 7 days of life, with LOS referring to presentation of sepsis after 7 days. Neonatal sepsis is the single most common cause of neonatal death in hospital as well as community in developing country.

Pain in babies, and whether babies feel pain, has been a large subject of debate within the medical profession for centuries. Prior to the late nineteenth century it was generally considered that babies hurt more easily than adults. It was only in the last quarter of the 20th century that scientific techniques finally established babies definitely do experience pain – probably more than adults – and developed reliable means of assessing and of treating it. As recently as 1999, it was widely believed by medical professionals that babies could not feel pain until they were a year old, but today it is believed newborns and likely even fetuses beyond a certain age can experience pain.

Diffuse neonatal hemangiomatosis (DNH) is a potentially fatal disorder where multiple benign (non-cancerous) blood vessel tumors (hemangiomas) are present in the skin and other organs. The mortality rate of diffuse neonatal hemangiomatosis is 50-90%. This disease is normally found in female Caucasian infants. The most common site of internal organ damage, or lesions, is the liver, which can redirect blood away from the heart and cause arteriovenous shunting. This can cause high cardiac output, leading to further complications such as congestive heart failure. This condition affecting the liver is also known as infantile hepatic hemangioma (IHH). Other sites of internal organ damage can include the intestines, nervous system, lungs, and sometimes the skeletal system. Early detection and treatment with steroids results in most newborn babies with this disease remaining healthy, with serious problems developing for some individuals during the hemangioma's growth phase.

<span class="mw-page-title-main">Neonatal resuscitation</span>

Neonatal resuscitation, also known as newborn resuscitation, is an emergency procedure focused on supporting approximately 10% of newborn children who do not readily begin breathing, putting them at risk of irreversible organ injury and death. Many of the infants who require this support to start breathing breath well on their own after assistance. Through positive airway pressure, and in severe cases chest compressions, medical personnel certified in neonatal resuscitation can often stimulate neonates to begin breathing on their own, with attendant normalization of heart rate.

<span class="mw-page-title-main">Gerhard Jorch</span> German pediatrician (born 1951)

Gerhard Jorch is a German pediatrician. He is Professor for general pediatrics and neonatology at the Otto-von-Guericke University of Magdeburg and director of the University children's hospital.

Perinatal stroke is a disease where an infant has a stroke between the 140th day of the gestation period and the 28th postpartum day, affecting up to 1 in 2300 live births. This disease is further divided into three subgroups, namely neonatal arterial ischemic stroke, neonatal cerebral sinovenous ischemic stroke, and presumed perinatal stroke. Several risk factors contribute to perinatal stroke including birth trauma, placental abruption, infections, and the mother's health.

<span class="mw-page-title-main">Henry Halliday (paediatrician)</span> British neonatologist (1945–2022)

Henry Lewis Halliday was a British-Irish paediatrician and neonatologist. In 2021, Halliday was awarded the James Spence Medal for research into neonatology, for coordinating two of the largest neonatal multicentre trials for prevention and treatment of a number of neonatal respiratory illnesses and for a breakthrough in the development of a new lung surfactant that brought relief to very small babies suffering from infant respiratory distress syndrome (RDS).

References

  1. 1 2 3 "Stefan Kutzsche". Store Norske Leksikon . 2014-09-28.
  2. Larsen, Øivind, ed. (1996). "Kutzsche, Stefan Paus". Norges leger[Physicians of Norway] (in Norwegian). Vol. 3. Oslo: Norwegian Medical Association. p. 452. ISBN   978-82-90921-43-4.
  3. Larsen, Øivind, ed. (2014). Doktorskole og medisinstudium: Det medisinske fakultet ved Universitetet i Oslo gjennom 200 år (1814–2014). Oslo: Norwegian Medical Society. p. 640. ISBN   978-82-92871-92-8.
  4. 1 2 "60 år: Dr.med. Stefan Kutzsche". Dagsavisen . 15 April 2014. p. 33.
  5. 1 2 3 Kutzsche, S (2003). "Oksygen ved fødselsasfyksi". Journal of the Norwegian Medical Association . 123 (11): 1545.
  6. "Godkjente spesialister i barnesykdommer". Norwegian Medical Association. Archived from the original on 17 November 2013. Retrieved 17 August 2015.
  7. "Godkjente spesialister i anestesiologi". Norwegian Medical Association. Archived from the original on 21 June 2017. Retrieved 17 August 2015.
  8. "The Quality of Internationally Trained Medical Doctors". University of Oslo . Retrieved 17 August 2015.
  9. 1 2 Kutzsche, S (2012). "Pedagogical training for health personnel". Journal of the Norwegian Medical Association . 132 (6): 628. doi: 10.4045/tidsskr.12.0112 . PMID   22456137.
  10. 1 2 "Utdanning i etikk for barneleger". Dagens Medisin. 9 September 2013. Retrieved 17 August 2015.
  11. Pedersen, Natasha, ed. (2016). Barnepalliasjon: mer enn omsorg ved livets slutt [Pediatric Palliative Care: More Than End-of-Life Care]. Foreningen for barnepalliasjon. p. 59. Dr. med. Stefan Kutzsche (f. 1954) er barnelege og anestesilege med mangeårig erfaring i omsorg og behandling av pasienter med akutt alvorlig sykdom eller skade. Han er ansatt på Nyfødtintensivavdelingen ved Oslo universitetssykehus.
  12. Kutzsche, S; Fugelseth, D (2013). "Trygg barseltid for nyfødte barn" (PDF). Journal of the Norwegian Medical Association . 133 (3): 270–1. doi: 10.4045/tidsskr.12.1222 . PMID   23381161.
  13. "Årsrapport 2005 Banak" (PDF). Finnmark Hospital Trust. Archived from the original (PDF) on 18 August 2015.
  14. "60 år: Dr.med. Stefan Kutzsche". Aftenposten . 15 April 2014. p. 35.
  15. "Team to steer uni to greater heights". The Star . 7 February 2016.
  16. "Et håndslag til barnehelse i Kambodsja". Paidos. 15 July 2019.
  17. "Stefan Kutzsche". Archived from the original on 2021-06-30. Retrieved 2024-01-13.
  18. Larsen, Øivind, ed. (2013). "Det medisinske fakultet i Oslo siden 1970-årene – et aktørseminar" (PDF). Michael . 10: 219–344. Archived from the original (PDF) on 2024-01-14.
  19. Bjørkhaug, Anders (2014). "Redaktøren". Paidos. 32 (2): 34. Retrieved 14 August 2015.
  20. "Medlemmer i spesialitetskomiteen for barnesykdommer". Norwegian Medical Association. Archived from the original on 27 October 2013.
  21. "Klinisk etikk-komité Oslo universitetssykehus, Ullevål og Aker sykehus". University of Oslo. Archived from the original on 27 June 2014.
  22. 1 2 "Centre for Bioethics and Humanities" . Retrieved 30 June 2021.
  23. "Editorial Board". Acta Paediatrica.
  24. Gupta, Sanjay (9 October 2013). "Sad Times, Tough Calls on the Pediatric Service". The Gupta Guide. Archived from the original on 2 December 2014. Retrieved 1 December 2014.
  25. Hofstad, Eivor (1998). "Gassforskning på Rikshospitalet" [Gas research at the National Hospital]. Legemidler og samfunn. No. 7. pp. 62–63. I Norge er det mellom 1200 og 1800 barn årlig som trenger gjenoppliving på grunn av oksygenmangel i forbindelse med fødselen (fødselsasfyksi). På Rikshospitalet pågår nå et prosjekt som vil evaluere dagens behandlingsformer [...] I prosjektet undersøker Kutzsche forskjellen på hvordan behandlingen fungerer med rent oksygen (dagens standardbehandling) i forhold til luft.
  26. Fugelsnes, Elin (19 October 2010). "Kan redde 200 000 nyfødte". Forskning.no . Retrieved 14 August 2015.