University of Pittsburgh Cancer Institute

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Hillman Cancer Center, home of the University of Pittsburgh Cancer Institute and UPMC Cancer Centers HillmanCancerCenterUPMC.jpg
Hillman Cancer Center, home of the University of Pittsburgh Cancer Institute and UPMC Cancer Centers

The University of Pittsburgh Cancer Institute (UPCI) is a National Cancer Institute (NCI)-designated Comprehensive Cancer Center located in the Hillman Cancer Center in the Shadyside neighborhood of Pittsburgh, Pennsylvania, United States. The only NCI-designated cancer center in Western Pennsylvania, UPCI is composed of collaborative academic and research efforts between the University of Pittsburgh, the University of Pittsburgh Medical Center (UPMC), and Carnegie Mellon University. [1] UPCI works in tandem with UPMC Cancer Centers to provide clinical cancer care to some 74,000 patients treated at its facilities at both the flagship Hillman Cancer Center location and at dozens of UPMC-affiliated sites throughout the Pittsburgh region as well as at a growing list of overseas locations. Founded in 1984, UPCI became the youngest cancer center in history to achieve NCI-designation, [2] and as of 2007 received nearly $200 million in funding from the National Cancer Institute ranking it in the top ten of all cancer research institutes. [1]

NCI-designated Cancer Centers are a group of 71 cancer research institutions in the United States supported by the National Cancer Institute.

Shadyside (Pittsburgh) Neighborhood of Pittsburgh in Allegheny County, Pennsylvania, United States

Shadyside is a neighborhood in the East End of Pittsburgh, Pennsylvania, United States. It has three zip codes and representation on Pittsburgh City Council by the council member for District 8. Shadyside is drawn from the name of a 19th-century Pennsylvania Railroad station in the area, which was named for its shady lanes.

Pittsburgh City in western Pennsylvania

Pittsburgh is a city in the Commonwealth of Pennsylvania in the United States, and is the county seat of Allegheny County. A population of about 301,048 residents live within the city limits, making it the 66th-largest city in the U.S. The metropolitan population of 2,324,743 is the largest in both the Ohio Valley and Appalachia, the second-largest in Pennsylvania, and the 27th-largest in the U.S.

Contents

Cancer Institute

The UPCI was founded in 1984 under the direction of Ronald B. Herberman, MD. [3] UPCI remains the only NCI-designated Comprehensive Cancer Center in Western Pennsylvania, and today is composed of 625 research faculty members specializing in disciplines ranging from cancer prevention and early detection to novel therapeutic discovery, survivorship, and end of life care. While most UPCI faculty maintain academic appointments at the University of Pittsburgh and physician-scientists maintain their clinical appointments through UPMC hospitals, some UPCI members are affiliated solely with UPMC or neighboring Carnegie Mellon University. Four target research areas of molecular and medical oncology at the institute include 1) the biological basis of cancer development and progression; 2) identification of new biomarkers for improved cancer detection and diagnosis; 3) the development of novel therapeutics for successful and comprehensive cancer treatment; and 4) establish and implement effect cancer prevention measures. [1] Over the last five years, UPCI's 350 faculty members have published more than 4,500 publications in peer-reviewed journals.

Oncology branch of medicine

Oncology is a branch of medicine that deals with the prevention, diagnosis, and treatment of cancer. A medical professional who practices oncology is an oncologist. The name's etymological origin is the Greek word ὄγκος (ónkos), meaning "tumor", "volume" or "mass" and the word λόγος (logos), meaning "study".

UPCI is ranked 12th in funding from the National Cancer Institute. It has increased its federal research funding to a total of nearly $174 million in 2011; up from totals of $154 million in 2007, $149 million in 2004, and $120 million in 2001. These totals include three competitive Specialized Program of Research Excellence (SPORE) grants focusing on head and neck, lung, and skin cancers. UPCI works in tandem with UPMC Cancer Centers Network to translate the latest research advances to clinical application for patients. UPCI also offers a variety of education, training programs and fellowships, in conjunction with related schools within the University of Pittsburgh, for both new cancer researchers to experienced investigators. [4] The current director of the UPCI and UPMC Cancer Centers is Nancy E. Davidson, MD. [3]

UPMC CancerCenter

UPMC CancerCenter works in tandem with the UPCI to offer the latest advances in cancer prevention, detection, diagnosis, and treatment to patients at UPMC-affiliated locations throughout the Pittsburgh region and abroad. The centers combine to create a network of more than 2,300 physicians, scientists, administrative staff, and other health care professionals that provide the latest care, technology, and treatments, as well as clinical trials, to over 36,000 patients each year. [3] UPMC CancerCenter encompass 13 areas of expertise, each focusing on a specific type or treatment of cancer. These include programs devoted to melanoma, brain cancers, breast cancer, colon and gastrointestinal cancers, head and neck cancers, leukemias and lymphomas, liver cancer, lung cancer, gynecologic cancers, prostate and urologic cancers, and stem cell transplantation. Pediatric cancers are treated by specialists at the UPMC Children's Hospital of Pittsburgh. [5]

Melanoma malignant neoplasm originating from melanocytes

Melanoma, also known as malignant melanoma, is a type of cancer that develops from the pigment-containing cells known as melanocytes. Melanomas typically occur in the skin, but may rarely occur in the mouth, intestines, or eye. In women, they most commonly occur on the legs, while in men they are most common on the back. Sometimes they develop from a mole with changes such as an increase in size, irregular edges, change in color, itchiness, or skin breakdown.

Brain tumor type of tumor

A brain tumor occurs when abnormal cells form within the brain. There are two main types of tumors: cancerous (malignant) tumors and benign (non-cancerous) tumors. Cancerous tumors can be divided into primary tumors, which start within the brain, and secondary tumors, which have spread from elsewhere, known as brain metastasis tumors. All types of brain tumors may produce symptoms that vary depending on the part of the brain involved. These symptoms may include headaches, seizures, problems with vision, vomiting and mental changes. The headache is classically worse in the morning and goes away with vomiting. Other symptoms may include difficulty walking, speaking or with sensations. As the disease progresses, unconsciousness may occur.

Breast cancer cancer that originates in the mammary gland

Breast cancer is cancer that develops from breast tissue. Signs of breast cancer may include a lump in the breast, a change in breast shape, dimpling of the skin, fluid coming from the nipple, a newly-inverted nipple, or a red or scaly patch of skin. In those with distant spread of the disease, there may be bone pain, swollen lymph nodes, shortness of breath, or yellow skin.

Locations

The network works as a hub-and-satellite system of cancer care services at locations that are tied to the central hub and the flagship facility of the UPMC CancerCenter Network and UPCI, the Hillman Cancer Center. The UPMC CancerCenter Network covers a geographic area of more than 200 miles (320 km) around greater Pittsburgh, comprising 180 affiliated oncologists at over 30 locations throughout Western Pennsylvania and Ohio and includes a growing list of international locations starting in Dublin and Waterford, Ireland and a radiotherapy center in Rome. [6] [7] In November, 2008, UPMC announced a partnership with GE Healthcare to open 25 additional cancer treatment centers across Europe and the Middle East over the next ten years. [8] [9]

Western Pennsylvania Place in Pennsylvania, United States

Western Pennsylvania refers to the western third of the state of Pennsylvania in the United States. Pittsburgh is the region's principal city, with a metropolitan area population of about 2.4 million people, and serves as its economic and cultural center. Erie, Altoona, and Johnstown are its other metropolitan centers. As of the 2010 census, Western Pennsylvania's total population is nearly 4 million.

Ireland Island in north-west Europe, 20th largest in world, politically divided into the Republic of Ireland and Northern Ireland (a part of the UK)

Ireland is an island in the North Atlantic. It is separated from Great Britain to its east by the North Channel, the Irish Sea, and St George's Channel. Ireland is the second-largest island of the British Isles, the third-largest in Europe, and the twentieth-largest on Earth.

Rome Capital of Italy

Rome is the capital city and a special comune of Italy. Rome also serves as the capital of the Lazio region. With 2,872,800 residents in 1,285 km2 (496.1 sq mi), it is also the country's most populated comune. It is the fourth most populous city in the European Union by population within city limits. It is the centre of the Metropolitan City of Rome, which has a population of 4,355,725 residents, thus making it the most populous metropolitan city in Italy. Rome is located in the central-western portion of the Italian Peninsula, within Lazio (Latium), along the shores of the Tiber. The Vatican City is an independent country inside the city boundaries of Rome, the only existing example of a country within a city: for this reason Rome has been often defined as capital of two states.

Pittsburgh Locations

  • Hillman Cancer Center (Primary Location), Pittsburgh, PA
  • Mary Hillman Jennings Radiation Oncology Center at Shadyside Hospital, Pittsburgh, PA
  • UPMC CancerCenter at Magee-Womens Hospital of UPMC, Pittsburgh, PA
  • UPMC CancerCenter at UPMC Mercy, Pittsburgh, PA
  • UPMC CancerCenter at UPMC St. Margaret, Pittsburgh, PA
UPMC Mercy Hospital in Pennsylvania, United States

UPMC Mercy is a main hospital facility of the University of Pittsburgh Medical Center (UPMC) and is located in the Uptown section of the city of Pittsburgh, Pennsylvania, adjacent to Duquesne University, and a few blocks from the PPG Paints Arena and downtown Pittsburgh. It is the first chartered hospital to have been founded in the city of Pittsburgh and it is also the first hospital in the world to have been established by the Sisters of Mercy. It is also the first teaching hospital in the region, accepting residents to teaching positions beginning in 1848, one year after opening its doors.

Locations North of Pittsburgh

Locations South of Pittsburgh

Locations East of Pittsburgh

Locations West of Pittsburgh

International Locations

  • Beacon Hospital Cancer Centre, Dublin, Ireland
  • UPMC Whitfield Cancer Centre, Waterford, Ireland
  • UPMC San Pietro FBF Advanced Radiotherapy Center, Rome, Italy

Hillman Cancer Center

Hillman Cancer Center is the flagship facility for the clinical services of UPMC Cancer Centers and research activities for the UPCI. The $130 million, 350,000-square-foot, 5-story facility, designed by Pittsburgh architectural firm IKM, opened in 2002 in the Shadyside neighborhood of Pittsburgh. It is located directly across Centre Avenue from, and connected via a pedestrian bridge to, UPMC Shadyside hospital where cancer surgery and Intensity Modulated Radiation Therapy (IMRT) are conducted. [10] [11] The Hillman Cancer Center building houses both a research pavilion and a clinical pavilion connected by a three-story atrium. The facility brings together 400 full-time researchers and clinicians and 185 physicians practicing in the UPMC Cancer Centers network. The clinical pavilion offers cancer prevention, risk assessment, detection, treatment, and stress and symptom management services including radiology services such as magnetic resonance imaging (MRI), ultrasound, computed tomography (CT) and positron emission tomography (PET). [12] It also includes waiting rooms equipped with televisions and play areas for children and access to a kitchen stocked with beverages and light refreshments. The outpatient clinic, known as The William Cooper Pavilion, honoring the oncologist who led the campaign for philanthropic support of the center, was designed by architectural firm Radelet McCarthy. [11] The Hillman Cancer Center also offers other amenities for patients including valet parking, a patient and family education and information center, a garden and meditation with a granite fountain, a café, gift shop and a salon where patients can receive salon services and purchase wigs, hats, skin care products and prostheses. [13]

In 2012, the Hillman Cancer Center opened the Mario Lemieux Center for Blood Cancers on the fourth floor of the building. The center is dedicated to former Pittsburgh Penguins hockey player Mario Lemieux, who was diagnosed with Hodgkin's lymphoma in 1993 and was cured. [14]

A prominent sculpture at the center is the bronze "Circle of Care" by Tuck Langland of Granger, Indiana. [15]

Notable people associated with the Institute

See also

Related Research Articles

Roswell Park Comprehensive Cancer Center Hospital in New York, United States

Roswell Park Comprehensive Cancer Center is a cancer research and treatment center and a New York State public-benefit corporation located in Buffalo, New York and founded by Roswell Park. Candace S. Johnson is President & Chief Executive Officer of Roswell Park Comprehensive Cancer Center. In 2018, Roswell Park ranked #30 on U.S. News & World Report's list of the best cancer hospitals in the country. Roswell Park was the first dedicated medical facility for cancer treatment and research in the United States, and is the only upstate New York facility to hold the National Cancer Institute designation of "comprehensive cancer center." Roswell Park Comprehensive Cancer Center, which conducts clinical research on cancer as well as developing new drugs, provides advanced treatment for all forms of adult and pediatric cancer and serves as a member of the National Comprehensive Cancer Network.

University of Pittsburgh Medical Center Global medical organization

The University of Pittsburgh Medical Center (UPMC) is a $19 billion integrated global nonprofit health enterprise that has 85,000 employees, 40 hospitals with more than 8,000 licensed beds, 600 clinical locations including outpatient sites and doctors' offices, a 3.4 million-member health insurance division, as well as commercial and international ventures. It is closely affiliated with its academic partner, the University of Pittsburgh. It is considered a leading American health care provider, as its flagship facilities have ranked in U.S. News & World Report "Honor Roll" of the approximately 15 to 20 best hospitals in America for over 15 years. As of 2016, UPMC is ranked 12th nationally among the best hospitals by U.S. News & World Report and ranked in 15 of 16 specialty areas when including UPMC Magee-Womens Hospital. This does not include UPMC Children's Hospital of Pittsburgh which ranked in the top 10 of pediatric centers in a separate US News ranking.

University of Pittsburgh School of Medicine medical school located in Pittsburgh, Pennsylvania

The University of Pittsburgh School of Medicine (UPSOM) is a medical school located in Pittsburgh, Pennsylvania. The School of Medicine, also known as Pitt Med, is consistently ranked as a "Top Medical School" by U.S. News & World Report in both research and primary care. UPSOM is currently ranked 13th in the category of research and 14th in primary care by U.S. News for 2020, and is separately ranked 17th in the Academic Ranking of World Universities list of best medical schools in the world. The school encompasses both a medical program, offering the doctor of medicine, and graduate programs, offering doctor of philosophy and master's degrees in several areas of biomedical science, clinical research, medical education, and medical informatics.

Cooper University Hospital Hospital in New Jersey, US

Cooper University Hospital is a teaching hospital and biomedical research facility located in Camden, New Jersey. The hospital formerly served as a clinical campus of Robert Wood Johnson Medical School and the University of Medicine and Dentistry of New Jersey. It is currently affiliated with the newly established Cooper Medical School of Rowan University and offers training programs across a variety of fields for medical students, residents, fellows, nurses, and allied health professionals. In 2013, Cooper announced a partnership with the University of Texas MD Anderson Cancer Center and opened a new comprehensive cancer center to serve patients in New Jersey and the Delaware Valley. Cooper also is affiliated with the Coriell Institute for Medical Research, a leading non-profit research organization that focuses on stem cell science, genomics and personalized medicine. Cooper is a tertiary partner for 21 hospitals in the region who can transfer their critically ill patients to Cooper University Hospital.

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Allegheny Health Network

Allegheny Health Network (AHN), based in Pittsburgh, is a non-profit, eight-hospital academic medical system with facilities located in Western Pennsylvania and one hospital in Western New York. The second-largest provider of health care in its region and one of the largest providers in Pennsylvania, AHN was formed in 2013 when Highmark Inc., a Pennsylvania-based Blue Cross Blue Shield insurance carrier, purchased the assets of the West Penn Allegheny Health System (WPAHS) and added three more hospitals to its new provider division. Allegheny Health Network was formed to act as the parent company to the WPAHS hospitals and its affiliate hospitals, while Highmark Health today serves as the ultimate parent of AHN, creating one of the nation's largest integrated health delivery and financing systems.

UPMC St. Margaret Hospital in Pennsylvania, United States

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Ronald B. Herberman was a physician, immunologist, oncologist, researcher, and professor of medicine and pathology who founded the University of Pittsburgh Cancer Institute (UPCI), a National Cancer Institute (NCI)-designated Comprehensive Care Center in 1984. He helped discover natural killer cells capable of killing cancer. He became well known outside the medical community in 2008 for his public warning about the potential health impacts of mobile telephones and recommending a reduction in their use.

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References

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  2. Levine, Arthur S. MD; Detre, Thomas P. MD; McDonald, Margaret C. PhD MFA; Roth, Loren H. MD MPH; Huber, George A. JD; Brignano, Mary Germann MA; Danoff, Sandra N. MSHS; Farner, David M.; Masnick, Jeffrey L. MBA MS; Romoff, Jeffrey A. MPhil (September 2008). "The Relationship Between the University of Pittsburgh School of Medicine and the University of Pittsburgh Medical Center—A Profile in Synergy". Academic Medicine. Lippincott Williams & Wilkins. 83 (9): 816–26. doi:10.1097/ACM.0b013e318181d1a8. ISSN   1040-2446. PMID   18728434 . Retrieved 2013-10-18.Cite uses deprecated parameter |deadurl= (help)
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  5. "About UPMC Cancer Centers - Overview" . Retrieved 2009-08-26.
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  7. "UPMC Cancer Centers -- Network Locations" . Retrieved 2009-08-19.
  8. Mitchell, Susan (2008-11-23). "UPMC planning to open 25 cancer centres outside Ireland". The Sunday Business Post. Cork, Ireland. Retrieved 2008-08-26.
  9. Schmid, John (2008-11-12). "GE, medical center team up to build cancer centers worldwide". Milwaukee-Wisconsin Journal Sentinel. Retrieved 2008-08-26.
  10. "Gallery - Category: Hillman Cancer Center". IKM. Retrieved 2008-08-26.
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  12. Steele, Bruce (2002-10-10). "Hillman Cancer Center opens". University Times. Retrieved 2009-08-26.
  13. "Hillman Cancer Center opens". Pittsburgh Business Times. 2002-10-09. Retrieved 2009-08-26.
  14. "UPMC'S Mario Lemieux Center for Blood Cancers opens in Shadyside". Pittsburgh Post-Gazette. 2012-12-24. Retrieved 2014-05-02.
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  16. "Cancer Epidemiology and Prevention Program (CEPP)" . Retrieved 17 March 2015.

Coordinates: 40°27′19″N79°56′32″W / 40.4553°N 79.9422°W / 40.4553; -79.9422