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Malaria is a mosquito-borne infectious disease that affects humans and other vertebrates. Human malaria causes symptoms that typically include fever, fatigue, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. Symptoms usually begin 10 to 15 days after being bitten by an infected Anopheles mosquito. If not properly treated, people may have recurrences of the disease months later. In those who have recently survived an infection, reinfection usually causes milder symptoms. This partial resistance disappears over months to years if the person has no continuing exposure to malaria.
Yellow fever is a viral disease of typically short duration. In most cases, symptoms include fever, chills, loss of appetite, nausea, muscle pains – particularly in the back – and headaches. Symptoms typically improve within five days. In about 15% of people, within a day of improving the fever comes back, abdominal pain occurs, and liver damage begins causing yellow skin. If this occurs, the risk of bleeding and kidney problems is increased.
Anopheles or Marsh Mosquitoes is a genus of mosquito first described and named by J. W. Meigen in 1818. About 460 species are recognized; while over 100 can transmit human malaria, only 30–40 commonly transmit parasites of the genus Plasmodium, which cause malaria in humans in endemic areas. Anopheles gambiae is one of the best known, because of its predominant role in the transmission of the most dangerous malaria parasite species – Plasmodium falciparum.
The o'nyong'nyong virus (ONNV) was first isolated by researchers at the Uganda Virus Research Institute in Entebbe, Uganda, during a large outbreak of a disease in 1959 that resembled dengue fever. ONNV is a togavirus, genus Alphavirus, is closely related to the chikungunya and Igbo Ora viruses, and is a member of the Semliki Forest antigenic complex. The name was given to the disease by the Acholi tribe during the 1959 outbreak. The name comes from the Nilotic language of Uganda and Sudan and means "weakening of the joints". The virus can infect humans and may cause disease.
The Suriya-Mal Movement was formed in the British colony of Ceylon to sell Suriya flowers on Poppy Day for the benefit of Sri Lankan ex-servicemen. The movement became anti-imperialist in character, and was also involved in relief work during the Malaria epidemic of 1934–1935.
Paratransgenesis is a technique that attempts to eliminate a pathogen from vector populations through transgenesis of a symbiont of the vector. The goal of this technique is to control vector-borne diseases. The first step is to identify proteins that prevent the vector species from transmitting the pathogen. The genes coding for these proteins are then introduced into the symbiont, so that they can be expressed in the vector. The final step in the strategy is to introduce these transgenic symbionts into vector populations in the wild. One use of this technique is to prevent mortality for humans from insect-borne diseases. Preventive methods and current controls against vector-borne diseases depend on insecticides, even though some mosquito breeds may be resistant to them. There are other ways to fully eliminate them. “Paratransgenesis focuses on utilizing genetically modified insect symbionts to express molecules within the vector that are deleterious to pathogens they transmit.” The acidic bacteria Asaia symbionts are beneficial in the normal development of mosquito larvae; however, it is unknown what Asais symbionts do to adult mosquitoes.
Globalization, the flow of information, goods, capital, and people across political and geographic boundaries, allows infectious diseases to rapidly spread around the world, while also allowing the alleviation of factors such as hunger and poverty, which are key determinants of global health. The spread of diseases across wide geographic scales has increased through history. Early diseases that spread from Asia to Europe were bubonic plague, influenza of various types, and similar infectious diseases.
Mosquito-borne diseases or mosquito-borne illnesses are diseases caused by bacteria, viruses or parasites transmitted by mosquitoes. Nearly 700 million people get a mosquito-borne illness each year resulting in over 725,000 deaths.
Anopheles (Cellia) subpictus is a species complex of four species of mosquito belonging to the genus Anopheles.
As of 2010, dengue fever is believed to infect 50 to 100 million people worldwide a year with 1/2 million life-threatening infections. It dramatically increased in frequency between 1960 and 2010, by 30 fold. This increase is believed to be due to a combination of urbanization, population growth, increased international travel, and global warming. The geographical distribution is around the equator with 70% of the total 2.5 billion people living in endemic areas from Asia and the Pacific. Many of the infected people during outbreaks are not virally tested, therefore their infections may also be due to chikungunya, a coinfection of both, or even other similar viruses.
Anopheles stephensi is a primary mosquito vector of malaria in urban India and is included in the same subgenus as Anopheles gambiae, the primary malaria vector in Africa. A. gambiae consists of a complex of morphologically identical species of mosquitoes, along with all other major malaria vectors; however, A. stephensi has not yet been included in any of these complexes. Nevertheless, two races of A. stephensi exist based on differences in egg dimensions and the number of ridges on the eggs; A. s. stephensisensu stricto, the type form, is a competent malaria vector that takes place in urban areas, and A. s. mysorensis, the variety form, exists in rural areas and exhibits considerable zoophilic behaviour, making it a poor malaria vector. However, A. s. mysorensis is a detrimental vector in Iran. An intermediate form also exists in rural communities and peri-urban areas, though its vector status is unknown. About 12% of malaria cases in India are due to A. stephensi.
Manavanna, also known as Manavarman in Indian sources, was king of Anuradhapura from 684 AD to 718 AD. Considered an important monarch of the Anuradhapura kingdom, he is known for concluding almost half a century of anarchy and ushering an era of prosperity within the nation.
Elizabethkingia anophelis is a yellow-pigmented, rod-shaped, gram-negative bacterium in the Flavobacteriaceae family. Elizabethkingia is isolated from the midgut of Anopheles gambiae G3 mosquitoes reared in captivity. The genus Elizabethkingia, named for former US Centers for Disease Control and Prevention (CDC) microbiologist Elizabeth O. King, also includes E. meningoseptica which causes neonatal sepsis and infections in immunocompromised persons, E. endophytica, and E. miricola.
Anopheles (Cellia) karwari is a species complex of zoophilic mosquito belonging to the genus Anopheles. It is found in India, and Sri Lanka, Bangladesh, Sumatra, and Java. A. karwari is a member of the Maculatus Group and the second scarcest species reported from Indonesia. Female is blood sucking and involved in transmitting Plasmodium falciparum, thus an important malarial vector. It is considered a secondary vector in the Australian region, but its vectorial status in South-East Asia was unknown.
Anopheles (Cellia) tessellatus is a species complex of zoophilic mosquito belonging to the genus Anopheles. It is found in India, and Sri Lanka, Bangladesh, Cambodia, China, Indonesia, Malaysia, Laos, Maldives, Myanmar, Nepal, Philippines, Taiwan, Thailand and Vietnam. It is first described from Sri Lanka. Larvae are known to found from dirty stagnant water in sun or shady habitats. Adults are zoophilic. It is not regarded as a malaria vector, but is a secondary vector of Wuchereria bancrofti in Maldives.
Airport malaria, sometimes known as baggage, luggage or suitcasemalaria, occurs when a malaria infected female Anopheles mosquito travels by aircraft from a country where malaria is common, arrives in a country where malaria is usually not found, and bites a person at or around the vicinity of the airport, or if the climate is suitable, travels in luggage and bites a person further away. The infected person usually presents with a fever in the absence of a recent travel history. There is often no suspicion of malaria, resulting in a delay in diagnosis. It is typically considered as a diagnosis after other explanations for symptoms have been ruled out.
Quartan fever is one of the four types of malaria which can be contracted by humans.
East Africa had a regional outbreak of Rift Valley fever in late 2006 that affected Kenya, Somalia, and Tanzania. During outbreak, 1062 people were infected with Rift Valley fever and 394 people died between December 2006 and December 2007. Rift Valley fever (RVF) is caused by a phlebovirus in the Bunyavirales order which is transmitted by mosquito bite and contact with infected animal blood; it mainly infects livestock that come into infectious contact with a viral reservoir but human beings can also be infected. The outbreak began after a heavy El Niño rain season across East Africa left greater than usual breeding ground for Aedes aegypti mosquitos, with particularly heavy rainfall over eastern Kenya, central Tanzania, and southern Somalia. While most people infected with the virus experience a relatively mild, flu-like illness without hospitalization, around 8% will develop a severe illness that can include eye disease, encephalitis, hemorrhagic fever and death. During this outbreak, of the 1,062 hospitalized, laboratory-confirmed RVF cases assays, 37% died.
Global climate change has resulted in a wide range of impacts on the spread of infectious diseases. Like other ways in which climate change affects on human health, climate change exacerbates existing inequalities and challenges in managing infectious disease. Infectious diseases whose transmission can be impacted by climate change include dengue fever, malaria, tick-borne diseases, leishmaniasis and Ebola virus disease. For example, climate change is altering the geographic range and seasonality of the mosquito that can carry dengue.
The dengue pandemic in Sri Lanka is part of the tropical disease dengue fever pandemic. Dengue fever is caused by Dengue virus, first recorded in the 1960s. It is not a native disease in this island. Present-day dengue has become a major public health problem. Aedes aegypti and Aedes albopictus are both mosquito species native to Sri Lanka. However, the disease did not emerge until the early 1960s. Dengue was first serologically confirmed in the country in 1962. A Chikungunya outbreak followed in 1965. In the early 1970s two type of dengue dominated in Sri Lanka: DENV-1 type1 and DENV-2 type 2. A total of 51 cases and 15 deaths were reported in 1965–1968. From 1989 onward, dengue fever has become endemic in Sri Lanka.
References
- 1 2 3 Wijesundere, Dilkushi Anula; Ramasamy, Ranjan (2017-08-28). "Analysis of Historical Trends and Recent Elimination of Malaria from Sri Lanka and Its Applicability for Malaria Control in Other Countries". Frontiers in Public Health. 5: 212. doi: 10.3389/fpubh.2017.00212 . ISSN 2296-2565. PMC 5581355 . PMID 28894732.
- 1 2 Gayan Dharmasiri, A. G.; Perera, A. Yashan; Harishchandra, Jeevanie; Herath, Hemantha; Aravindan, Kandasamy; Jayasooriya, H. T. R.; Ranawaka, Gaya R.; Hewavitharane, Mihirini (2017-08-10). "First record of Anopheles stephensi in Sri Lanka: a potential challenge for prevention of malaria reintroduction". Malaria Journal. 16 (1): 326. doi:10.1186/s12936-017-1977-7. ISSN 1475-2875. PMC 5553605 . PMID 28797253.
- ↑ "Anti Malaria Campaign | Sri Lanka - Anti Malaria Campaign | Sri Lanka". www.malariacampaign.gov.lk. Retrieved 2020-11-28.
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