5-hydroxypentanoate CoA-transferase

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5-hydroxypentanoate CoA-transferase
Identifiers
EC no. 2.8.3.14
CAS no. 111684-68-5
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In enzymology, a 5-hydroxypentanoate CoA-transferase (EC 2.8.3.14) is an enzyme that catalyzes the chemical reaction

acetyl-CoA + 5-hydroxypentanoate acetate + 5-hydroxypentanoyl-CoA

Thus, the two substrates of this enzyme are acetyl-CoA and 5-hydroxypentanoate, whereas its two products are acetate and 5-hydroxypentanoyl-CoA.

This enzyme belongs to the family of transferases, specifically the CoA-transferases. The systematic name of this enzyme class is acetyl-CoA:5-hydroxypentanoate CoA-transferase. Other names in common use include 5-hydroxyvalerate CoA-transferase, and 5-hydroxyvalerate coenzyme A transferase.

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<span class="mw-page-title-main">Coenzyme A transferases</span> Coenzyme A transferases

Coenzyme A transferases (CoA-transferases) are transferase enzymes that catalyze the transfer of a coenzyme A group from an acyl-CoA donor to a carboxylic acid acceptor. Among other roles, they are responsible for transfer of CoA groups during fermentation and metabolism of ketone bodies. These enzymes are found in all three domains of life.

References