Alpinumisoflavone

Alpinumisoflavone

Chemical structure of alpinumisoflavone
Names
IUPAC name 4′,5-Dihydroxy-6′′,6′′-dimethyl-6′′H-pyrano[3′′,2′′:6,7]isoflavone
Systematic IUPAC name 5-Hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-4H,8H-benzo[1,2-b:5,4-b′]dipyran-4-one
Other names 5-Hydroxy-3-(4-hydroxyphenyl)-8,8-dimethylpyrano[3,2-g]chromen-4-one
Identifiers
CAS Number	34086-50-5  Y
3D model (JSmol)	Interactive image Interactive image
ChEMBL	ChEMBL238628  Y
ChemSpider	4590280  Y
PubChem CID	5490139
UNII	6Q33HOF94Z  Y
CompTox Dashboard (EPA)	DTXSID00187683
InChI InChI=1S/C20H16O5/c1-20(2)8-7-13-15(25-20)9-16-17(18(13)22)19(23)14(10-24-16)11-3-5-12(21)6-4-11/h3-10,21-22H,1-2H3 Y Key: RQAMSFTXEFSBPK-UHFFFAOYSA-N Y InChI=1/C20H16O5/c1-20(2)8-7-13-15(25-20)9-16-17(18(13)22)19(23)14(10-24-16)11-3-5-12(21)6-4-11/h3-10,21-22H,1-2H3 Key: RQAMSFTXEFSBPK-UHFFFAOYAG
SMILES CC1(C=CC2=C(O1)C=C3C(=C2O)C(=O)C(=CO3)C4=CC=C(C=C4)O)C O=C2/C(c1ccc(O)cc1)=C\Oc4c2c(O)c3\C=C/C(Oc3c4)(C)C
Properties
Chemical formula	C20H16O5
Molar mass	336.33 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Y  verify  (what is  YN ?) Infobox references

Alpinumisoflavone is a pyranoisoflavone, a type of isoflavone.

Properties

It can be found in the bark of Rinorea welwitschii . ^[1] It can also be found in the molluscicide plant Millettia thonningii and is thought to be an antischistosomal agent ^[2] since it has been shown to kill the snails which transmit the schistosomiasis and also the larvae of the parasite itself. ^[3]

References

1. Stewart, M.; Bartholomew, B.; Currie, F.; Abbiw, D.K.; Latif, Z.; Sarker, S.D.; Nash, R.J. (2000). "Pyranoisoflavones from Rinorea welwitschii". Fitoterapia. 71 (5): 595–597. doi:10.1016/S0367-326X(00)00210-0. PMID   11449519.
2. Perrett, S.; Whitfield, P.J.; Sanderson, L.; Bartlett, A. (1995). "The plant molluscicide Millettia thonningii (Leguminosae) as a topical antischistosomal agent". Journal of Ethnopharmacology. 47 (1): 49–54. doi:10.1016/0378-8741(95)01253-a. PMID   7564421.
3. Perrett, Sheena; Whitfield, Philip J. (1995). "Aqueous degradation of isoflavonoids in an extract of Millettia thonningii (Leguminosae) which is larvicidal towards schistosomes". Phytotherapy Research. 9 (6): 401–404. doi:10.1002/ptr.2650090603. S2CID   85035592.