Names | |
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Preferred IUPAC name 7-Hydroxy-3-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one | |
Other names 7,3′-Dihydroxy-4′-methoxyisoflavone 3′,7-Dihydroxy-4′-methoxyisoflavone 3′-Hydroxyformononetin | |
Identifiers | |
3D model (JSmol) | |
ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.222.904 |
PubChem CID | |
UNII | |
CompTox Dashboard (EPA) | |
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Properties | |
C16H12O5 | |
Molar mass | 284.267 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
verify (what is ?) | |
Infobox references | |
Calycosin is an O-methylated isoflavone. It can be isolated from Astragalus membranaceus Bge. var. mongholicus [1] and Trifolium pratense L. (red clover). [2]
Isoflavone 3′-hydroxylase uses formononetin, NADPH, H+ and O2 to produce calycosin, NADP+ and H2O.
Clover or trefoil are common names for plants of the genus Trifolium, consisting of about 300 species of flowering plants in the legume or pea family Fabaceae originating in Europe. The genus has a cosmopolitan distribution with highest diversity in the temperate Northern Hemisphere, but many species also occur in South America and Africa, including at high altitudes on mountains in the tropics. They are small annual, biennial, or short-lived perennial herbaceous plants, typically growing up to 30 cm tall. The leaves are trifoliate, monofoil, bifoil, cinquefoil, hexafoil, septfoil, etcetera, with stipules adnate to the leaf-stalk, and heads or dense spikes of small red, purple, white, or yellow flowers; the small, few-seeded pods are enclosed in the calyx. Other closely related genera often called clovers include Melilotus and Medicago.
Forage is a plant material eaten by grazing livestock. Historically, the term forage has meant only plants eaten by the animals directly as pasture, crop residue, or immature cereal crops, but it is also used more loosely to include similar plants cut for fodder and carried to the animals, especially as hay or silage.
Trifolium pratense, the red clover, is a herbaceous species of flowering plant in the bean family Fabaceae, native to Europe, Western Asia, and northwest Africa, but planted and naturalized in many other regions.
Isoflavones are substituted derivatives of isoflavone, a type of naturally occurring isoflavonoids, many of which act as phytoestrogens in mammals. Isoflavones are produced almost exclusively by the members of the bean family, Fabaceae (Leguminosae).
Daidzein is a naturally occurring compound found exclusively in soybeans and other legumes and structurally belongs to a class of compounds known as isoflavones. Daidzein and other isoflavones are produced in plants through the phenylpropanoid pathway of secondary metabolism and are used as signal carriers, and defense responses to pathogenic attacks. In humans, recent research has shown the viability of using daidzein in medicine for menopausal relief, osteoporosis, blood cholesterol, and lowering the risk of some hormone-related cancers, and heart disease.
Astragalus propinquus (syn. Astragalus membranaceus, commonly known as Mongolian milkvetch in English; 'Хунчир' in Mongolian; huáng qí, běi qí or huáng huā huáng qí, in Mongolia, is a flowering plant in the family Fabaceae. It is one of the 50 fundamental herbs used in traditional Mongolian medicine. It is a perennial plant and it is not listed as being threatened.
Hepatoprotection or antihepatotoxicity is the ability of a chemical substance to prevent damage to the liver. This is opposite to hepatotoxicity.
Prenylated flavonoids or prenylflavonoids are a sub-class of flavonoids. They are widely distributed throughout the plant kingdom. Some are known to have phytoestrogenic or antioxidant properties. They are given in the list of adaptogens in herbalism. Chemically they have a prenyl group attached to their flavonoid backbone. It is usually assumed that the addition of hydrophobic prenyl groups facilitate attachment to cell membranes. Prenylation may increase the potential activity of its original flavonoid.
Retusin is an O-methylated isoflavone, a type of flavonoid. It can be found in Fabaceae species like Dipteryx odorata, in Dalbergia retusa and in Millettia nitida. It can also be found in Maackia amurensis cell cultures.
Irilone is an isoflavone, a type of flavonoid. It can be found in Trifolium pratense, in Iris unguicularis and in Iris germanica.
Pratensein is an O-methylated isoflavone, a type of flavonoid. It can be found in Trifolium pratense and can have effects for the prevention of atherosclerosis.
Kumatakenin is an O-methylated flavonol. It can be found in Astragalus membranaceus.
Barbigerone is one of a few pyranoisoflavones among several groups of isoflavones. It was first isolated from the seed of a leguminous plant Tephrosia barbigera; hence the name "barbigerone". Members of the genus Millettia are now known to be rich in barbigerone, including M. dielsiena, M. ferruginea, M. usaramensis, and M. pachycarpa. It has also been isolated from the medicinal plant Sarcolobus globosus. Barbigerone from S. globosus is validated to have significant antioxidant property. Barbigerone exhibits profound antiplasmodial activity against the malarial parasite Plasmodium falciparum. It is also demonstrated that it has anti-cancer potential as it causes apoptosis of murine lung-cancer cells.
8-Prenylnaringenin is a prenylflavonoid phytoestrogen. It is reported to be the most estrogenic phytoestrogen known. The compound is equipotent at the two forms of estrogen receptors, ERα and ERβ, and it acts as a full agonist of ERα. Its effects are similar to those of estradiol, but it is considerably less potent in comparison.
The flora of Lebanon includes approximately 2,600 plant species. Situated on the eastern coast of the Mediterranean Basin, Lebanon is a reservoir of plant diversity and one of the world's biodiversity hotspots for conservation priorities. Endemic species constitute 12% of the Lebanese flora; 221 plant species are broad endemics and 90 are narrow endemics. Important Plant Areas (IPAs) featuring the country exceptional botanical richness were defined in 2018.
Astragalosides are a series of related chemical compounds isolated from Astragalus membranaceus.
Penicillium albidum is an anamorph fungus species of the genus of Penicillium which was isolated from volcanic soils in the south of Chile. Penicillium albidum produces the antibiotic Albidin.
Pisatin (3-hydroxy-7-methoxy-4′,5′-methylenedioxy-chromanocoumarane) is the major phytoalexin made by the pea plant Pisum sativum. It was the first phytoalexin to be purified and chemically identified. The molecular formula is C17H14O6.