Angiokeratoma

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Angiokeratoma
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Angiokeratoma is a benign cutaneous lesion of capillaries, resulting in small marks of red to blue color and characterized by hyperkeratosis. Angiokeratoma corporis diffusum refers to Fabry's disease, [1] but this is usually considered a distinct condition.

Contents

Signs and symptoms

Presentation includes telangiectasia, acanthosis, and hyperkeratosis. [2]

Presentation can be solitary or systemic. [3]

Multiple angiokeratomas, especially on the trunk in young people, are typical for Fabry disease, genetic disorder connected with systemic complications.

Complications

In some instances nodular angiokeratomas can produce necrotic tissue and valleys that can harbor fungal, bacterial and viral infections. Infections can include staphylococcus. If the lesion becomes painful, begins draining fluids or pus, or begins to smell, consult a physician. In these instance a doctor may recommend excision and grafting.

Pathophysiology

Histology

Angiokeratomas characteristically have large dilated blood vessels in the superficial dermis and hyperkeratosis (overlying the dilated vessels).

Diagnosis

Due to the rarity of different types of vascular conditions, angiokeratomas may be misdiagnosed. A biopsy of the lesion can produce a more accurate diagnosis.[ citation needed ]

Classification

Angiokeratoma may be classified as:

Treatment

Outpatient treatments such as interventional radiology, lasers, and physical therapy are employed to reduce the severity of the vascular lesions. However, in some cases lasers have caused a reaction in the tissue causing it to expand and become exposed to infection. Excision and grafting may be necessary to remove the lesion. Recovery time on such an operation ranges from 3 to 12 weeks depending on location of the graft, healing time and the possibility of complications.[ citation needed ]

See also

Related Research Articles

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References

  1. Trickett R, Dowd H (October 2006). "Angiokeratoma of the scrotum: a case of scrotal bleeding". Emerg Med J. 23 (10): e57. doi:10.1136/emj.2006.038745. PMC   2579622 . PMID   16988295.
  2. " angiokeratoma " at Dorland's Medical Dictionary
  3. Sion-Vardy N, Manor E, Puterman M, Bodner L (January 2008). "Solitary angiokeratoma of the tongue" (PDF). Med Oral Patol Oral Cir Bucal. 13 (1): E12–4. PMID   18167473.
  4. Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN   978-1-4160-2999-1.
  5. 1 2 3 4 5 James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN   0-7216-2921-0.
  6. Mibelli's disease II @ Who Named It