Clinical data | |
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Trade names | Zelsuvmi |
Other names | SB206 |
License data | |
Routes of administration | Topical |
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Chemical and physical data | |
Formula | Indeterminate [1] |
Molar mass | Indeterminate [1] |
Berdazimer sodium, sold under the brand name Zelsuvmi, is a medication used for the treatment for molluscum contagiosum. [1] Berdazimer sodium is a nitric oxide releasing agent. [1] It is a polymer formed from sodium 1-hydroxy-3-methyl-3-(3-(trimethoxysilyl)propyl)-1-triazene-2-oxide and tetraethyl silicate. [2]
Berdazimer sodium was approved for medical use in the United States in January 2024. [3] [4] [5]
Berdazimer sodium is indicated for the topical treatment of molluscum contagiosum. [1]
Application site reactions, including allergic contact dermatitis, have occurred in patients treated with Zelsuvmi (Berdazimer sodium). Suspect allergic contact dermatitis in the event of pain, pruritus, swelling or erythema at the application site lasting longer than 24 hours. If allergic contact dermatitis occurs, discontinue ZELSUVMI and initiate appropriate therapy.
Berdazimer sodium is a nitric oxide releasing agent. The mechanism of action for the treatment of molluscum contagiosum is unknown.
Berdazimer sodium was approved for medical use in the United States in January 2024. [4]
Berdazimer sodium is the international nonproprietary name. [6]
Molluscum contagiosum (MC), sometimes called water warts, is a viral infection of the skin that results in small raised pink lesions with a dimple in the center. They may become itchy or sore, and occur singularly or in groups. Any area of the skin may be affected, with abdomen, legs, arms, neck, genital area, and face being the most common. Onset of the lesions is around seven weeks after infection. They usually go away within a year without scarring.
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Mapracorat is an anti-inflammatory drug belonging to the experimental class of selective glucocorticoid receptor agonists (SEGRAs). It is in clinical trials for the topical treatment of atopic dermatitis, inflammation following cataract surgery, and allergic conjunctivitis. Preliminary investigation for the treatment of keratoconjunctivitis sicca has been conducted in cellular models.
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