Ibacitabine

Last updated
Ibacitabine
Ibacitabine.svg
Names
IUPAC name
2′-Deoxy-5-iodocytidine
Systematic IUPAC name
4-Amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidin-2(1H)-one
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.009.337 OOjs UI icon edit-ltr-progressive.svg
KEGG
PubChem CID
UNII
  • InChI=1S/C9H12IN3O4/c10-4-2-13(9(16)12-8(4)11)7-1-5(15)6(3-14)17-7/h2,5-7,14-15H,1,3H2,(H2,11,12,16)/t5-,6+,7+/m0/s1 X mark.svgN
    Key: WEVJJMPVVFNAHZ-RRKCRQDMSA-N X mark.svgN
  • InChI=1/C9H12IN3O4/c10-4-2-13(9(16)12-8(4)11)7-1-5(15)6(3-14)17-7/h2,5-7,14-15H,1,3H2,(H2,11,12,16)/t5-,6+,7+/m0/s1
    Key: WEVJJMPVVFNAHZ-RRKCRQDMBC
  • OCC1[C@@H](O)C[C@@H](O1)N2C=C(I)C(N)=NC2=O
Properties
C9H12IN3O4
Molar mass 353.11375
Pharmacology
D06BB08 ( WHO )
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Ibacitabine (or ibacitabin, [1] or 5-iodo-2'-deoxycytidine ) is an antiviral drug. It is topically applied to treat herpes labialis. [2]

Related Research Articles

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<span class="mw-page-title-main">Aciclovir</span> Antiviral medication used against herpes, chickenpox and shingles

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<span class="mw-page-title-main">Ganciclovir</span> Chemical compound

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<span class="mw-page-title-main">Imiquimod</span> Chemical compound

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Idoxuridine is an anti-herpesvirus antiviral drug.

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Clotrimazole, sold under the brand name Lotrimin, among others, is an antifungal medication. It is used to treat vaginal yeast infections, oral thrush, diaper rash, tinea versicolor, and types of ringworm including athlete's foot and jock itch. It can be taken by mouth or applied as a cream to the skin or in the vagina.

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Herpes simplex is a viral infection caused by the herpes simplex virus. Infections are categorized based on the part of the body infected.

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A cold sore, also known as a fever blister and herpes labialis, is a type of infection by the herpes simplex virus that affects primarily the lip. Symptoms typically include a burning pain followed by small blisters or sores. The first attack may also be accompanied by fever, sore throat, and enlarged lymph nodes. The rash usually heals within ten days, but the virus remains dormant in the trigeminal ganglion. The virus may periodically reactivate to create another outbreak of sores in the mouth or lip.

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<span class="mw-page-title-main">William Prusoff</span>

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References

  1. Serpentier-Daude, A.; Collet, E.; Didier, A. F.; Touraud, J. P.; Sgro, C.; Lambert, D. (February 2000). "[Contact dermatitis to topical antiviral drugs]". Ann Dermatol Venereol. 127 (2): 191–3. PMID   10739980.
  2. Groot, Anton C. de (2021). Topical drugs (First ed.). Boca Raton, FL: CRC Press. p. 421. ISBN   9781000367867.