Blood group B linear chain alpha-1,3-galactosidase

Baicalin-beta-D-glucuronidase
Identifiers
EC no.	3.2.1.167
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Baicalin-beta-D-glucuronidase (EC 3.2.1.167, baicalinase) is an enzyme with systematic name 5,6,7-trihydroxyflavone-7-O-beta-D-glucupyranosiduronate glucuronosylhydrolase. ^{[1] [2] [3] [4]} This enzyme catalyses the following chemical reaction

baicalin + H₂O ${\displaystyle \rightleftharpoons }$ baicalein + D-glucuronate

The enzyme also hydrolyses wogonin 7-O-beta-D-glucuronide and oroxylin 7-O-beta-D-glucuronide with lower efficiency.

References

1. Ikegami F, Matsunae K, Hisamitsu M, Kurihara T, Yamamoto T, Murakoshi I (November 1995). "Purification and properties of a plant beta-D-glucuronidase form Scutellaria root". Biological & Pharmaceutical Bulletin. 18 (11): 1531–4. doi: 10.1248/bpb.18.1531 . PMID   8593473.
2. Zhang C, Zhang Y, Chen J, Liang X (2005). "Purification and characterization of baicalin-β-D-glucuronidase hydrolyzing baicalin to baicalein from fresh roots of Scutellaria viscidula Bge". Proc. Biochem. 40 (5): 1911–1915. doi:10.1016/j.procbio.2004.07.003.
3. Sasaki K, Taura F, Shoyama Y, Morimoto S (September 2000). "Molecular characterization of a novel beta-glucuronidase from Scutellaria baicalensis georgi". The Journal of Biological Chemistry. 275 (35): 27466–72. doi: 10.1074/jbc.m004674200 . PMID   10858442.
4. Morimoto S, Harioka T, Shoyama Y (1995). "Purification and characterization of flavone-specific β-glucuronidase from callus cultures of Scutellaria baicalensis Georgi". Planta. 195 (4): 535–540. Bibcode:1995Plant.195..535M. doi:10.1007/bf00195712.

External links

• Baicalin-beta-D-glucuronidase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)