Brigham and Women's Hospital

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Brigham and Women's Hospital
Mass General Brigham
Brigham and Womens Hospital logo.svg
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Brigham and Women's Hospital
Geography
Location75 Francis Street
Boston, Massachusetts, United States
Coordinates 42°20′10″N71°06′25″W / 42.336152°N 71.106834°W / 42.336152; -71.106834
Organization
Type Teaching
Affiliated university Harvard University
Services
Emergency department Level I trauma center
Beds793
Helipad FAA LID: MA39
History
Opened1980
Links
Website brighamandwomens.org
Lists Hospitals in Massachusetts

Brigham and Women's Hospital (BWH) is the second largest teaching hospital of Harvard Medical School and the largest hospital in the Longwood Medical Area in Boston, Massachusetts. Along with Massachusetts General Hospital, it is one of the two founding members of Mass General Brigham, the largest healthcare provider in Massachusetts. Robert Higgins, MD, MSHA serves as the hospital's current president. [1]

Contents

Brigham and Women's Hospital conducts the second largest (behind MGH) hospital-based research program in the world, with an annual research budget of more than $630 million. [2] Pioneering achievements at BWH have included the world's first successful heart valve operation and the world's first solid organ transplant.

History

221 Longwood Avenue, formerly the Boston Lying-In Hospital building, part of Brigham and Women's Hospital but separate from the main building at 15-75 Francis Street; view from Longwood Avenue Bwh-longwood.jpg
221 Longwood Avenue, formerly the Boston Lying-In Hospital building, part of Brigham and Women's Hospital but separate from the main building at 15–75 Francis Street; view from Longwood Avenue
Former site of the Free Hospital for Women across the street from Olmsted Park. This institution was absorbed into Brigham and Women's Hospital. Free Hospital for Women.jpg
Former site of the Free Hospital for Women across the street from Olmsted Park. This institution was absorbed into Brigham and Women's Hospital.

Brigham and Women's Hospital was established with the 1980 merger of three Harvard-affiliated hospitals: Peter Bent Brigham Hospital (established in 1913); Robert Breck Brigham Hospital (established in 1914); and Boston Hospital for Women (established in 1966 as a merger of Boston Lying-In Hospital, established in 1832, and Free Hospital for Women, established in 1875).[ citation needed ]

In 1954, the Peter Bent Brigham Hospital became the location for the first-ever successful kidney transplant, performed on identical twins, Ronald Hendrick (the donor) and Richard Hendrick (the recipient). J. Hartwell Harrison, Chief of the Urology Department, operated on the donor, and Joseph Murray was the surgeon for the recipient. Murray later received a Nobel Prize for this and other work. Dr. Samuel A. Levine introduced the arm-chair treatment of myocardial infarction in the 1950s and his protégé Dr. Bernard Lown was an early innovator in the development of the coronary care unit in the 1960s. [3]

After a 10-year affiliation with Faulkner Hospital in the Jamaica Plain section of Boston, BWH merged with the community hospital in 2012 to form Brigham and Women's Faulkner Hospital. [4]

In April 2017, Brigham and Women's announced they would be offering voluntary buyouts to 1,600 staff in an effort to control costs. The hospital was profitable, but this move was due to higher labor and other costs amid stagnant payments from insurance companies. The hospital also needs to pay for two large projects, a $550 million new outpatient and research building that opened the previous year and a $335 million new software system launched in 2015. [5]

Also in April 2017, the United States District Court for the District of Massachusetts announced that Brigham and Women's Hospital and its nonprofit hospital and physicians network, Partners HealthCare, agreed to pay a $10 million fine to resolve allegations that a stem cell research lab fraudulently obtained federal grant funding. [6]

After 11 years as the president of Brigham and Women's Hospital, Dr. Elizabeth Nabel, will step down to pursue opportunities in the for-profit biotech sector. She will leave the position as of March 1, 2021 and join a biotech firm co-founded by her husband Gary Nabel and Elias Zerhouni. [7]

In the late 2010s, Brigham Health contracted with Evergrande to provide medical training and consulting to set up the private Boao Evergrande International Hospital in China for patients who could afford to pay. The venture struggled due to lack of patients; the contract was allowed to lapse and Brigham branding was removed by mid-2021. The relatively remote location of Boao compared to population centers of wealthy Chinese was blamed for the failure. [8]

Core service lines

Quality and safety

In the early 1990s, BWH pioneered Computerized Physician Order Entry (CPOE) to prevent medication errors. BWH has received patient safety awards for its electronic Medication Administration Record (eMAR) and barcoding system, which places barcodes on patients' medications, name bands, and nurses' badges. A nurse scans all three barcodes before administering a medication to ensure that each patient receives the correct medication and dosage at the correct time. [9] [10]

The orthopedic surgery department focused on patients' satisfaction for those who received knee and hip replacements. Leaders in the department included John Wright, Mary Anne Kenyon, and Carolyn Beagan, but they gave little attention to holding costs down. [11]

Research

In 2013, the BWH Biomedical Research Institute (BRI) received $630 million in research support from all sources. For over a decade, it has been one of the two hospitals receiving the most National Institutes of Health (NIH) funding among independent hospitals in the United States. It employs over 3,300 researchers.[ citation needed ]

BRI has worked on regenerative medicine, designing nanoparticles to attack different cancer types and starting a clinical trial for a type of Alzheimer's disease vaccine. BWH research also includes population studies including the Nurses' Health Study and Physicians' Health Study. [9]

The 21st century has seen dramatic shifts in the diagnostic and therapeutic approach to lung carcinomas, beginning with the discovery of epidermal growth factor receptor (EGFR) mutations and their role in directing management with targeted tyrosine kinase inhibitors. Since 2003, this has reshaped the approach at BWH's molecular diagnostic testing center. [12]

In 2017, the hospital began the first human clinical trials to reverse the aging process using NAD+. The trials are headed by biologist David Andrew Sinclair. [13]

In 2019, BWH opened the Brigham Preventive Genomics Clinic, [14] becoming one of the first hospitals in the United States [15] to offer DNA sequencing, reporting, and interpretation of disease-associated genes to healthy patients seeking to reduce their risk of future disease. [16]

Related Research Articles

<span class="mw-page-title-main">Harvard Medical School</span> Medical school in Boston, Massachusetts, US

Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area in Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States. Unlike most other leading medical schools, HMS does not operate in conjunction with a single hospital but is directly affiliated with several teaching hospitals in the Boston area. Affiliated teaching hospitals and research institutes include Dana–Farber Cancer Institute, Massachusetts General Hospital, Brigham and Women's Hospital, Beth Israel Deaconess Medical Center, Boston Children's Hospital, McLean Hospital, Cambridge Health Alliance, The Baker Center for Children and Families, and Spaulding Rehabilitation Hospital.

<span class="mw-page-title-main">Massachusetts General Hospital</span> Hospital in Massachusetts, United States

Massachusetts General Hospital is the original and largest teaching hospital of Harvard Medical School, Harvard University located in the West End neighborhood of Boston, Massachusetts. Massachusetts General Hospital houses the world's largest hospital-based research program, the Mass General Research Institute, with an annual research budget of more than $1.2 billion in 2021. It is the third-oldest general hospital in the United States with a patient capacity of 999 beds. Along with Brigham and Women's Hospital, Mass General is a founding member of Mass General Brigham, formerly known as Partners HealthCare, the largest healthcare provider in Massachusetts. It is currently ranked as the eighth-best hospital in the United States by U.S. News & World Report.

<span class="mw-page-title-main">Mass General Brigham</span> Health Care System Based in Greater Boston, Massachusetts

Mass General Brigham is a not-for-profit, integrated health care system that is a national leader in medical research, teaching, and patient care. It is the largest hospital-based research enterprise in the United States, with annual funding of more than $2 billion. The system's annual revenue was nearly $18 billion in 2022. It is also an educational institution, founded by Brigham and Women's Hospital and Massachusetts General Hospital. The system provides clinical care through two academic hospitals, three specialty hospitals, seven community hospitals, home care services, a health insurance plan, and a robust network of specialty practices, urgent care facilities, and outpatient clinics/surgical centers. It is the largest private employer in Massachusetts. In 2023, the system reported that from 2017–2021 its overall economic impact was $53.4 billion – more than the annual state budget.

Salem Hospital, formerly known as North Shore Medical Center, is a Level III trauma center located in Salem, Massachusetts. A member of Mass General Brigham since 1996, it offers comprehensive medical and surgical services and includes emergency/trauma departments and a birthplace. It includes Salem Hospital and the Mass General Brigham Healthcare Center in Lynn, as well as outpatient care and urgent care. The Medical Staff includes nearly 800 affiliated physicians representing primary care, family practice and 50 additional sub-specialties. It is affiliated with Tufts University School of Medicine.

<span class="mw-page-title-main">Bernard Lown</span> American inventor and cardiologist (1921–2021)

Bernard Lown was a Lithuanian-American cardiologist and inventor. Lown was the original developer of the direct current defibrillator for cardiac resuscitation, and the cardioverter for correcting rapid disordered heart rhythms. He introduced a new use for the drug lidocaine to control heartbeat disturbances.

<span class="mw-page-title-main">Elizabeth Nabel</span> American academic

Elizabeth Nabel is an American cardiologist and Executive Vice President of Strategy at ModeX Therapeutics and OPKO Health. Prior to this role, she served as President of Brigham Health and its Brigham and Women's Hospital, Professor of Medicine at Harvard Medical School, and Director of the NIH's National Heart, Lung, and Blood Institute.

<span class="mw-page-title-main">Carola B. Eisenberg</span> American psychiatrist (1917–2021)

Carola Blitzman Eisenberg was an Argentine-American psychiatrist who became the first woman to hold the position of dean of students at Massachusetts Institute of Technology. From 1978 to 1990, she was the dean of student affairs at Harvard Medical School (HMS). She has for a long time been lecturer in the newly renamed Department of Global Health and Social Medicine at HMS. She was also both a founding member of Physicians for Human Rights and an honorary psychiatrist with the Massachusetts General Hospital in Boston, a longstanding position there.

<span class="mw-page-title-main">Myrtelle Canavan</span> American physician (1879-1953)

Myrtelle May Moore Canavan was an American physician and medical researcher. She was one of the first female pathologists and is best known for publishing a description of Canavan disease in 1931.

George Constantin Cotzias was a Greek scientist who together with his coworkers developed L-Dopa treatment, currently the most commonly used treatment for Parkinson's disease.

Allan Macy Butler (1894–1986) was an American pediatrician and Chief of the Children's Medical Services at Massachusetts General Hospital and a professor of Pediatrics at Harvard Medical School. A pioneer in health services, Butler sought to change the structure of the American ‘fee-for-service’ system of health care to one based on government-paid medical care for the elderly and low-income people.

<span class="mw-page-title-main">Leona Baumgartner</span> American physician (1902–1991)

Leona Baumgartner was an American physician. She was the first woman to serve as Commissioner of New York City's Department of Health (1954–1962). She was a strong advocate of health education and a pioneer in promoting health services among New York's immigrant and poverty-stricken population.

David Davis Rutstein (1909-1986) was a long-time faculty member at Harvard Medical School and an advocate for preventive medicine. He was one of the first physicians to use television as an outreach tool to inform the public about health concerns and research. Rutstein also played a national role in the organization of medical care in the United States, the integration of preventive medicine into patient care, and the measurement of medical outcomes.

Matthew H. Liang is a physician specializing in social rheumatology, Professor of Medicine at Harvard Medical School, Professor of Health Policy and Management at Harvard School of Public Health, and the Director of Special Projects of the Robert B. Brigham Arthritis and Musculoskeletal Diseases Clinical Research Center which he founded. At the Brigham and Women's Hospital he is Medical Director of Rehabilitation Services. He is a founding faculty of the Division of General Internal Medicine and Primary Care at the Brigham and Women's Hospital and a founding faculty of the Clinical Effectiveness Program at the Harvard School of Public Health and is a Study Director in the Veterans Administration Cooperative Studies Program.

<span class="mw-page-title-main">Ferenc A. Jolesz</span> Hungarian-American physician

Ferenc Andras Jolesz was a Hungarian-American physician and scientist best known for his research on image guided therapy, the process by which information derived from diagnostic imaging is used to improve the localization and targeting of diseased tissue to monitor and control treatment during surgical and interventional procedures. He pioneered the field of Magnetic Resonance Imaging-guided interventions and introduced of a variety of new medical procedures based on novel combinations of imaging and therapy delivery.

Howard Haym Hiatt is a medical researcher involved with the discovery of messenger RNA. He was the past chair of the department of medicine at Beth Israel Hospital in Boston from 1963-1972. He was past dean of the Harvard School of Public Health from 1972–1984. He was co-founder and associate chief of the Division of Social Medicine and Health Inequalities at the Brigham and Women's Hospital, and was also the Associate Chief of the hospital's Division of Global Health Equity. He was a founding head of the cancer division of Beth Israel Hospital. He was a member of the team at the Pasteur Institute, Paris, led by Francois Jacob and Jacques Monod, which first identified and described messenger RNA, and he was part of the team led by James Watson that was among the first to demonstrate messenger RNA in mammalian cells.

Paula Adina Johnson is a cardiologist and the current president of Wellesley College. She is the first Black woman to serve in this role. The first Black graduate of Wellesley College came in the year 1887, and 129 years later President Johnson became the first Black leader. Prior to her role as president of Wellesley, Johnson founded and served as the inaugural executive director of the Mary Horrigan Connors Center for Women's Health & Gender Biology, as well as Chief of the Division of Women's Health at Brigham and Women's Hospital. Dr. Johnson's background in working for the betterment of women in the field of health led her on a notable path to Wellesley College, a women's college right outside of Boston, where there is an emphasis on the role of women in STEM.

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Abraham Clifford Barger was an American professor of physiology who spent his entire career at Harvard Medical School. His research focused on the pathophysiology of heart failure and on the role of the kidneys in hypertension. Barger served as the president of the American Physiological Society in 1970-71 and was elected to the Institute of Medicine in 1974.

Dr. Elizabeth Connell was an American doctor and proponent of women's reproductive health.

Mariana Castells is a Spanish-American allergist who focuses on mast cell diseases, including mastocytosis, mast cell activation syndrome and hereditary alpha tryptasimia. Mastocytosis is a rare disease with limited treatment options. Castells works at Brigham and Women's Hospital in Massachusetts in the Department of Allergy, Rheumatology, and Immunology and at the Dana Farber Cancer Institute. She is also a professor of medicine at Harvard Medical School.

References

  1. "Robert Higgins, MD, MSHA President, Brigham and Women's Hospital". Brigham and Women's Hospital. Brigham Health. Retrieved 15 February 2023.
  2. "Awards, Honors & Grants News – Brigham and Women's Hospital".
  3. Julian, D (September 2001). "The evolution of the coronary care unit". Cardiovascular Research. 51 (4): 621–624. doi: 10.1016/S0008-6363(01)00365-0 . PMID   11530092.
  4. "Preliminary Review of PHS Proposed Acquisition" (PDF). mass.gov. Commonwealth of Massachusetts Health Policy Commission. 18 December 2013. pp. 1, 5. Archived from the original (PDF) on 17 March 2014. Retrieved 8 November 2014. PHS is now called Mass General Brigham
  5. Dayal McCluskey, Priyanka (2017-04-27). "Brigham and Women's offers buyouts to 1,600 workers". The Boston Globe . Retrieved 2017-04-27.
  6. Finucane, Martin (2017-04-27). "Partners, Brigham and Women's to pay $10m in research fraud case". The Boston Globe . Retrieved 2017-04-27.
  7. Dayal McCluskey, Priyanka (2021-01-05). "Brigham and Women's president to step down". The Boston Globe . Retrieved 2021-03-10.
  8. Deirdre Fernandes; Rebecca Ostriker; Liz Kowalczyk; Patricia Wen (December 26, 2021). "How Brigham Health helped create a Chinese hospital for elites — and almost nobody came". The Boston Globe .
  9. 1 2 3 "Boston Hospital & Medical Center". Brigham and Women's Hospital. Archived from the original on 11 May 2020. Retrieved 2 April 2018.
  10. Thomas W. Cooley, et al. "Implementation of computerized prescriber order entry in four academic medical centers," American Journal of Health-System Pharmacy (12/15/2012) 69#24 pp 2166–2173
  11. "Patients Come First at Brigham and Women's Department of Orthopedic Surgery," Journal of Bone and Joint Surgery, American Volume (March 2013) Special Report, Jeffrey Shyu, p17-23.
  12. Neal Lindeman, "Molecular Diagnostics of Lung Cancers at the Brigham and Women's Hospital and Dana-Farber Cancer Institute: Technology in Rapid Evolution", Archives of Pathology & Laboratory Medicine (Oct 2012) 136#10 pp. 1198–1200. PMID   23020723, doi : 10.5858/arpa.2012-0277-RA.
  13. "Scientists unveil a giant leap for anti-aging". ScienceDaily . Retrieved 2 April 2018.
  14. "Brigham and Women's launches preventive genomics clinic". Beckers Hospital Review.
  15. "Concierge DNA Testing: Boston Doctors And Genetic Counselors Consult, But It Will Cost You". www.wbur.org.
  16. Robbins,STAT, Rebecca. "Top U.S. Medical Centers Roll Out DNA Sequencing Clinics for Healthy Clients". Scientific American.