Charles Swanton

Last updated

Charles Swanton
FRS FMedSci FRCP
Charles Swanton Royal Society.jpg
Swanton in 2018
Born
Robert Charles Swanton

1972 (age 52–53) [1]
Poole, Dorset, England, UK [1]
Education St Paul's School, London
Alma mater University College London (MD, PhD)
Awards Ellison–Cliffe Lecture (2017)
EMBO Member (2017)
Scientific career
FieldsCancer evolution [2]
Institutions Francis Crick Institute
University College London
Thesis Viral cyclin disruption of mammalian cell cycle control mechanisms  (1998)
Doctoral advisor Nic Jones
Website www.crick.ac.uk/research/a-z-researchers/researchers-p-s/charles-swanton/

Robert Charles Swanton is a British physician scientist specialising in oncology and cancer research. Swanton is a senior group leader at London's Francis Crick Institute, [3] Royal Society Napier Professor in Cancer [4] and thoracic medical oncologist at University College London [5] and University College London Hospitals, [6] [7] co-director of the Cancer Research UK (CRUK) Lung Cancer Centre of Excellence, and Chief Clinician of Cancer Research UK. [8] [9]

Contents

Early life and education

Swanton was born in Poole, Dorset. As of 2017, his father Robert Howard Swanton (MD, FRCP) was a consultant cardiologist at UCL. [10]

Swanton was educated at St Paul's School, London [1] and completed his PhD in 1999 [11] at what was then the Imperial Cancer Research Fund Laboratories (now the Francis Crick Institute) and his Cancer Research UK clinician scientist/medical oncology training in 2008. [7]

Career

Professor Swanton speaking at a conference in 2015 Professor Charles Swanton.jpg
Professor Swanton speaking at a conference in 2015

Swanton has combined [ when? ] his laboratory research with clinical duties as co-director of the CRUK Lung Cancer Centre, focussed on how tumours evolve over space and time. [7] He has helped to define the branched evolutionary histories of solid tumours, processes that drive cancer cell-to-cell variation in the form of new cancer mutations or chromosomal instabilities, and the impact of such cancer diversity on effective immune surveillance and clinical outcome. [2] [7] [12] [13]

As of 2018, Swanton has been a co-founder of Achilles Therapeutics [14] with Sergio Quezada, Karl Peggs and Mark Lowdell. Achilles Therapeutics is a UCL/CRUK and Francis Crick Institute [15] biotechnology company funded by Syncona [16] that develops adoptive T cell therapies targeting clonal/truncal neo-antigens present in every tumour cell to limit drug resistance and tumour evolution.[ citation needed ]

Awards and honours

Personal life

References

  1. 1 2 3 Anon (2017). "Swanton, Prof. (Robert) Charles" . Who's Who (online Oxford University Press  ed.). Oxford: A & C Black. doi:10.1093/ww/9780199540884.013.U286524.(Subscription or UK public library membership required.)
  2. 1 2 Charles Swanton publications indexed by Google Scholar OOjs UI icon edit-ltr-progressive.svg
  3. ↑ "Charles Swanton – The Francis Crick Institute". crick.ac.uk. 28 April 2025.
  4. ↑ Anon (2016). "Leading scientists awarded Royal Society Research Professorships". royalsociety.org. Royal Society . Retrieved 27 November 2018.
  5. ↑ "Iris View Profile". iris.ucl.ac.uk. Archived from the original on 22 May 2017. Retrieved 12 January 2022.
  6. ↑ "The UCLH lung cancer service". uclh.nhs.uk. Retrieved 27 November 2018.
  7. 1 2 3 4 5 6 Anon (2018). "Professor Charles Swanton FMedSci FRS". London: Royal Society. One or more of the preceding sentences incorporates text from the royalsociety.org website where:
    "All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License." -- "Terms, conditions and policies | Royal Society". Archived from the original on 11 November 2016. Retrieved 27 June 2018.{{cite web}}: CS1 maint: bot: original URL status unknown (link)
  8. ↑ "Chief Executive and Executive Board". 27 September 2013.
  9. ↑ Charles Swanton publications from Europe PubMed Central
  10. ↑ Anon (2017). "Swanton, Robert Howard" . Who's Who (online Oxford University Press  ed.). Oxford: A & C Black. doi:10.1093/ww/9780199540884.013.U4000216.(Subscription or UK public library membership required.)
  11. ↑ Swanton, Robert Charles (1998). Viral cyclin disruption of mammalian cell cycle control mechanisms. london.ac.uk (PhD thesis). University College London (University of London). OCLC   941060556. EThOS   uk.bl.ethos.286205.
  12. ↑ Swanton, Charles; Mann, David J.; Fleckenstein, Bernhard; Neipel, Frank; Peters, Gordon; Jones, Nic (1997). "Herpes viral cyclin/Cdk6 complexes evade inhibition by CDK inhibitor proteins". Nature. 390 (6656): 184–187. Bibcode:1997Natur.390..184S. doi:10.1038/36606. ISSN   0028-0836. PMID   9367157. S2CID   4397584.
  13. ↑ Charles Swanton publications indexed by the Scopus bibliographic database. (subscription required)
  14. ↑ "Our Team – Achilles Therapeutics". achillestx.com. Retrieved 27 November 2018.
  15. ↑ UCL (5 October 2016). "UCL spin-out Achilles Therapeutics to develop immunotherapies for cancer". UCL News. Retrieved 27 November 2018.
  16. ↑ "Achilles Therapeutics". Syncona. Retrieved 27 November 2018.
  17. ↑ "Pontecorvo Prize for best PhD thesis". cancerresearchuk.org. 28 October 2015. Retrieved 27 November 2018.
  18. ↑ "Professor Charles Swanton – The Academy of Medical Sciences". acmedsci.ac.uk. Retrieved 27 November 2018.
  19. ↑ Systems, eZ. "List of Award Winners / Fondazione San Salvatore". fondazionesansalvatore.ch. Archived from the original on 22 July 2018. Retrieved 27 November 2018.
  20. ↑ "Translational Cancer Research Prize". cancerresearchuk.org. 28 October 2015. Retrieved 27 November 2018.
  21. ↑ Jukic, Igor. "EMBO welcomes 65 new members". Embo.org. Archived from the original on 27 September 2017. Retrieved 27 November 2018.
  22. ↑ "Kraft Prize Symposium – Massachusetts General Hospital, Boston, MA". massgeneral.org. Retrieved 27 November 2018.
  23. ↑ Azvolinsky, Anna (2018). "Cancer Evolutionist: A Profile of Charles Swanton". The Scientist .
  24. ↑ Louis-Jeantet Prize 2024

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