Cleistanthus collinus | |
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Scientific classification ![]() | |
Kingdom: | Plantae |
Clade: | Tracheophytes |
Clade: | Angiosperms |
Clade: | Eudicots |
Clade: | Rosids |
Order: | Malpighiales |
Family: | Phyllanthaceae |
Genus: | Cleistanthus |
Species: | C. collinus |
Binomial name | |
Cleistanthus collinus | |
Synonyms | |
Lebidieropsis orbiculata var. lambertii Contents |
Cleistanthus collinus [2] is a plant species first described by Roxburgh, with its current name after Bentham and Hooker; it is included in the family Phyllanthaceae. [3] [4] The IUCN categorizes this species as vulnerable. [1] No subspecies are listed in the Catalogue of Life. [3]
Cleistanthus collinus (Karra) contains a plant poison also called oduvan (Tamil), kadise (Kannada), Vadisaku (Telugu), Oduku (Malayalam) and Gaja Madara (Sinhala) . Ingestion of its leaves or a decoction of its leaves causes hypokalemia (kaliuresis and cardiac arrhythmias), [5] metabolic acidosis, hypotension and hypoxia [6] probably due to distal renal tubular acidosis, ARDS and toxin induced vasodilatation respectively. [7] [8] [9] Hypokalemia and acidosis probably also induces rhabdomyolysis resulting in myoglobinuric kidney failure and neuromuscular weakness. [10] Its effects are probably mediated by injury to the distal renal tubules, pulmonary epithelium and peripheral blood vessels due to glutathione depletion [11] (animal studies have shown benefit with N-acetylcysteine). [12]