| Garcinia benthamiana | |
|---|---|
Scientific classification  | |
| Kingdom: | Plantae |
| Clade: | Tracheophytes |
| Clade: | Angiosperms |
| Clade: | Eudicots |
| Clade: | Rosids |
| Order: | Malpighiales |
| Family: | Clusiaceae |
| Genus: | Garcinia |
| Species: | G. benthamiana |
| Binomial name | |
| Garcinia benthamiana | |
| Synonyms | |
Garcinia benthamiana, also known as asashi, is a flowering tree in the family Clusiaceae (Guttiferae). The specific epithet (benthamiana) honors English botanist George Bentham. [2]
Garcinia benthamiana is native to central Brazil, northern Peru, Guyana, Suriname, and French Guiana. [3]
Its petiolate leaves are elliptical to ovate in shape and measure 12–28 centimeters (4.7–11.0 inches) in length and 4.5–11 centimeters (1.8–4.3 inches) in width. The apex can be rounded, acute or acuminate, while the base is rounded to attenuate. It has fasciculate and axillary inflorescences, and the flowers have 15–25 stamens. The fruit has a verrucose epicarp and preeminent rostrum, with a smooth, elliptic seed. Its bark is rough and dark red-brown in color, sometimes covered in a green or white mold. It is a dioecious and evergreen tree. [4] [3]
Four xanthones, α-mangostin, β-mangostin, mangostenol, mangaxanthone B, three benzophenones, mangaphenone, benthamianone, congestiflorone, and one sterol, stigmasterol, were isolated from the stem bark of Garcinia benthamiana. Α-mangostin, β-mangostin, mangaxanthone B and mangaphenone showed significant cytotoxicity through MTT assay against MCF-7 and MDA-MB-231 cells with IC50 values ranging from 4.4 to 12 µM. Mangaphenone showed no toxicity toward Vero cells, showing its potential as a lead compound for anti-breast cancer drugs. [5]
Garcinia is a genus of flowering plants in the family Clusiaceae native to Asia, America, Australia, tropical and southern Africa, and Polynesia. The number of species is disputed; Plants of the World Online (POWO) recognise up to 400. Commonly, the plants in this genus are called saptrees, mangosteens, or garcinias, and is one of several plants known as by the name "monkey fruit".
Betulinic acid is a naturally occurring pentacyclic triterpenoid which has antiretroviral, antimalarial, and anti-inflammatory properties, as well as a more recently discovered potential as an anticancer agent, by inhibition of topoisomerase. It is found in the bark of several species of plants, principally the white birch from which it gets its name, but also the ber tree, selfheal, the tropical carnivorous plants Triphyophyllum peltatum and Ancistrocladus heyneanus, Diospyros leucomelas, a member of the persimmon family, Tetracera boiviniana, the jambul, flowering quince, rosemary, and Pulsatilla chinensis.
Persin is a fungicidal toxin present in the avocado. Persin is an oil-soluble compound structurally similar to a fatty acid, and it leaches into the body of the fruit from the seeds.
Handroanthus impetiginosus, the pink ipê, pink lapacho or pink trumpet tree, is a tree in the family Bignoniaceae, distributed throughout North, Central and South America, from northern Mexico south to northern Argentina. Along with all the other species in the Handroanthus genus, it is the national tree of Paraguay.
Flueggea flexuosa is a species of plant in the family Phyllanthaceae. It is native to the Philippines, Indonesia, Vanuatu and the Solomon Islands and it is classified under "least concern" by the IUCN. The wood of this plant is usually used as building materials particularly as rafter, house post or agricultural implements. In the Philippines, this plant is locally known as anislag, tras or malagau.
Lymphotoxin-alpha (LT-α) formerly known as tumor necrosis factor-beta (TNF-β) is a protein that in humans is encoded by the LTA gene. Belonging to the hematopoietic cell line, LT-α exhibits anti-proliferative activity and causes the cellular destruction of tumor cell lines. As a cytotoxic protein, LT-α performs a variety of important roles in immune regulation depending on the form that it is secreted as. Unlike other members of the TNF superfamily, LT-α is only found as a soluble homotrimer, when found at the cell surface it is found only as a heterotrimer with LTβ.
Garcinia morella is a species of tree in the family Clusiaceae found in India, and Sri Lanka.
Premna serratifolia is a small tree/shrub in the family Lamiaceae. It flowers and fruits between May and November. During flowering season, it attracts a large number of butterflies and bees. Synonyms of Premna serratifolia Linn. include P. corymbosa Merr., P. integrifolia L. and P. obtusifolia R. Br.).
Garcinia indica, a plant in the mangosteen family (Clusiaceae), commonly known as kokum, is a fruit-bearing tree that has culinary, pharmaceutical, and industrial uses. It primarily grows in the Western Ghats, especially the Goa and Konkan region.
Tubulin inhibitors are chemotherapy drugs that interfere directly with the tubulin system, which is in contrast to those chemotherapy drugs acting on DNA. Microtubules play an important role in eukaryotic cells. Alpha- and beta-tubulin, the main components of microtubules, have gained considerable interest because of their function and biophysical properties and has become the subject of intense study. The addition of tubulin ligands can affect microtubule stability and function, including mitosis, cell motion and intracellular organelle transport. Tubulin binding molecules have generated significant interest after the introduction of the taxanes into clinical oncology and the general use of the vinca alkaloids. These compounds inhibit cell mitosis by binding to the protein tubulin in the mitotic spindle and preventing polymerization or depolymerization into the microtubules. This mode of action is also shared with another natural agent called colchicine.
Garcinia nigrolineata has been called "wild beaked Kandis" and is a tree species in the family Clusiaceae. The Catalogue of Life lists no subspecies.
Goniothalamus maewongensis is a species of plant in the family Annonaceae. It is native to Thailand. Richard M.K. Saunders and Piya Chalermglin, who first formally described the species, named it after the Mae Wong National Park in Thailand where the type specimen was collected.
Garcinia forbesii, commonly known as the rose kandis or kandis, is a small to medium-sized tree in the family Clusiaceae (Guttiferae). The specific epithet (forbesii) honors Scottish naturalist Henry Ogg Forbes.
Garcinia pseudoguttifera, known as the mo'onia tree in its native range, is a species of flowering tree in the family Clusiaceae (Guttiferae). The specific epithet (pseudoguttifera) comes from Greek pseudo and Neo-Latin guttifera.
Garcinia mannii is a dioecious and evergreen flowering tree in the family Clusiaceae (Guttiferae). The specific epithet (mannii) honors German botanist Gustav Mann.
Couepia polyandra, also known as olosapo, zapote amarillo, baboon cap, and monkey cap, is a flowering tree in the family Chrysobalanaceae.
Eugenia calycina, also known as savannah cherry, field cherry, Jabuti cherry, Grao de galo, cerejinha, cereja de cerrado, pitanga-vermelha, red pitanga, pitanga cherry of cerrado, and ca-ajaboti, is a flowering shrub in the family Myrtaceae. The specific epithet (calycina) comes from Latin calycinus, meaning having a notable calyx.
Annona cherimolioides is a species of plant in the Annonaceae family. It is native to Colombia and Ecuador. José Jerónimo Triana and Jules Émile Planchon, the botanists who first formally described the species, named it after its resemblance to another Annona species A. cherimoya.
Uvariopsis congensis is a species of plant in the Annonaceae family. It is native to Angola, Cameroon, the Central African Republic, the Democratic Republic of the Congo, Gabon, Ivory Coast, Kenya, Sudan, Uganda, Zambia. Walter Robyns and Jean Ghesquière, the botanists who first formally described the species, named it after the Belgian Congo, now called the Democratic Republic of the Congo, where the specimen they examined was collected in the town of Kisantu near the Inkisi River.
