Glycoside hydrolase family 44

Last updated
Glycoside hydrolase family 44
Identifiers
SymbolGlyco_hydro_44
Pfam PF12891
Pfam clan CL0058
CAZy GH44
Available protein structures:
Pfam   structures / ECOD  
PDB RCSB PDB; PDBe; PDBj
PDBsum structure summary

In molecular biology, glycoside hydrolase family 44 is a family of glycoside hydrolases.

Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families. [1] [2] [3] This classification is available on the CAZy web site, [4] [5] and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes. [6] [7]

Glycoside hydrolase family 44 CAZY GH_44, formerly known as cellulase family J, includes enzymes with endoglucanase EC 3.2.1.4 and xyloglucanase EC 3.2.1.151 activities. The overall structure of enzymes in this family consists of a TIM-like barrel domain, a beta-sandwich domain and an active site with two glutamic acid residues, all of which are conserved between the endoglucanases and xyloglucanases in the family, with only minor differences. [8] [9]

Related Research Articles

<span class="mw-page-title-main">Glycoside hydrolase family 10</span>

In molecular biology, Glycoside hydrolase family 10 is a family of glycoside hydrolases.

<span class="mw-page-title-main">Glycoside hydrolase family 12</span>

In molecular biology, Glycoside hydrolase family 12 is a family of glycoside hydrolases.

<span class="mw-page-title-main">Glycoside hydrolase family 20</span>

In molecular biology, glycoside hydrolase family 20 is a family of glycoside hydrolases.

<span class="mw-page-title-main">Glycoside hydrolase family 32</span> Family of glycoside hydrolases

In molecular biology, glycoside hydrolase family 32 is a family of glycoside hydrolases.

<span class="mw-page-title-main">Glycoside hydrolase family 35</span>

In molecular biology, glycoside hydrolase family 35 is a family of glycoside hydrolases.

<span class="mw-page-title-main">Glycoside hydrolase family 4</span>

In molecular biology, glycoside hydrolase family 4 is a family of glycoside hydrolases EC 3.2.1., which are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families. This classification is available on the CAZy web site, and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.

<span class="mw-page-title-main">Glycoside hydrolase family 45</span>

In molecular biology, glycoside hydrolase family 45 is a family of glycoside hydrolases.

<span class="mw-page-title-main">Glycoside hydrolase family 46</span>

In molecular biology, glycoside hydrolase family 46 is a family of glycoside hydrolases.

<span class="mw-page-title-main">Glycoside hydrolase family 48</span>

In molecular biology, glycoside hydrolase family 48 is a family of glycoside hydrolases.

<span class="mw-page-title-main">Glycoside hydrolase family 49</span>

In molecular biology, glycoside hydrolase family 49 is a family of glycoside hydrolases.

<span class="mw-page-title-main">Glycoside hydrolase family 68</span>

In molecular biology, glycoside hydrolase family 68 is a family of glycoside hydrolases.

<span class="mw-page-title-main">Glycoside hydrolase family 7</span> Enzyme family

In molecular biology, glycoside hydrolase family 7 is a family of glycoside hydrolases EC 3.2.1., which are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families. This classification is available on the CAZy web site, and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.

In molecular biology, glycoside hydrolase family 92 is a family of glycoside hydrolases.

In molecular biology, glycoside hydrolase family 98 is a family of glycoside hydrolases.

In molecular biology, glycoside hydrolase family 9 is a family of glycoside hydrolases.

In molecular biology, glycoside hydrolase family 5 is a family of glycoside hydrolases EC 3.2.1., which are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families. This classification is available on the CAZy web site, and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.

In molecular biology, glycoside hydrolase family 6 is a family of glycoside hydrolases EC 3.2.1., which are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families. This classification is available on the CAZy web site, and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.

In molecular biology, glycoside hydrolase family 8 is a family of glycoside hydrolases EC 3.2.1., which are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families. This classification is available on the CAZy website, and also discussed at CAZypedia, an online encyclopedia of carbohydrate-active enzymes.

<span class="mw-page-title-main">Glycoside hydrolase family 13</span>

In molecular biology, glycoside hydrolase family 13 is a family of glycoside hydrolases.

In molecular biology, glycoside hydrolase family 75 is a family of glycoside hydrolases.

References

  1. Henrissat B, Callebaut I, Fabrega S, Lehn P, Mornon JP, Davies G (July 1995). "Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases". Proceedings of the National Academy of Sciences of the United States of America. 92 (15): 7090–4. Bibcode:1995PNAS...92.7090H. doi: 10.1073/pnas.92.15.7090 . PMC   41477 . PMID   7624375.
  2. Davies G, Henrissat B (September 1995). "Structures and mechanisms of glycosyl hydrolases". Structure. 3 (9): 853–9. doi: 10.1016/S0969-2126(01)00220-9 . PMID   8535779.
  3. Henrissat B, Bairoch A (June 1996). "Updating the sequence-based classification of glycosyl hydrolases". The Biochemical Journal. 316 (Pt 2): 695–6. doi:10.1042/bj3160695. PMC   1217404 . PMID   8687420.
  4. "Home". CAZy.org. Retrieved 2018-03-06.
  5. Lombard V, Golaconda Ramulu H, Drula E, Coutinho PM, Henrissat B (January 2014). "The carbohydrate-active enzymes database (CAZy) in 2013". Nucleic Acids Research. 42 (Database issue): D490-5. doi:10.1093/nar/gkt1178. PMC   3965031 . PMID   24270786.
  6. "Glycoside Hydrolase Family 44". CAZypedia.org. Retrieved 2018-03-06.
  7. CAZypedia Consortium (December 2018). "Ten years of CAZypedia: a living encyclopedia of carbohydrate-active enzymes". Glycobiology. 28 (1): 3–8. doi: 10.1093/glycob/cwx089 . PMID   29040563.
  8. Kitago Y, Karita S, Watanabe N, Kamiya M, Aizawa T, Sakka K, Tanaka I (December 2007). "Crystal structure of Cel44A, a glycoside hydrolase family 44 endoglucanase from Clostridium thermocellum". The Journal of Biological Chemistry. 282 (49): 35703–11. doi: 10.1074/jbc.M706835200 . PMID   17905739.
  9. Ariza A, Eklöf JM, Spadiut O, Offen WA, Roberts SM, Besenmatter W, Friis EP, Skjøt M, Wilson KS, Brumer H, Davies G (September 2011). "Structure and activity of Paenibacillus polymyxa xyloglucanase from glycoside hydrolase family 44". The Journal of Biological Chemistry. 286 (39): 33890–900. doi: 10.1074/jbc.M111.262345 . PMC   3190823 . PMID   21795708.