Help Conquer Cancer is a volunteer computing project that runs on the BOINC platform. It is a joint project of the Ontario Cancer Institute and the Hauptman-Woodward Medical Research Institute. It is also the first project under World Community Grid to run with a GPU counterpart. [1]
The goal is to enhance the efficiency of protein X-ray crystallography, which will enable researchers to determine the structure of many cancer-related proteins faster. This will lead to improving the understanding of the function of these proteins, and accelerate the development of new pharmaceutical drugs.
Grid computing is the use of widely distributed computer resources to reach a common goal. A computing grid can be thought of as a distributed system with non-interactive workloads that involve many files. Grid computing is distinguished from conventional high-performance computing systems such as cluster computing in that grid computers have each node set to perform a different task/application. Grid computers also tend to be more heterogeneous and geographically dispersed than cluster computers. Although a single grid can be dedicated to a particular application, commonly a grid is used for a variety of purposes. Grids are often constructed with general-purpose grid middleware software libraries. Grid sizes can be quite large.
The Berkeley Open Infrastructure for Network Computing is an open-source middleware system for volunteer computing. Developed originally to support SETI@home, it became the platform for many other applications in areas as diverse as medicine, molecular biology, mathematics, linguistics, climatology, environmental science, and astrophysics, among others. The purpose of BOINC is to enable researchers to utilize processing resources of personal computers and other devices around the world.
grid.org was a website and online community established in 2001 for cluster computing and grid computing software users. For six years it operated several different volunteer computing projects that allowed members to donate their spare computer cycles to worthwhile causes. In 2007, it became a community for open source cluster and grid computing software. After around 2010 it redirected to other sites.
Predictor@home was a volunteer computing project that used BOINC software to predict protein structure from protein sequence in the context of the 6th biannual CASP, or Critical Assessment of Techniques for Protein Structure Prediction. A major goal of the project was the testing and evaluating of new algorithms to predict both known and unknown protein structures.
World Community Grid (WCG) is an effort to create the world's largest volunteer computing platform to tackle scientific research that benefits humanity. Launched on November 16, 2004, with proprietary Grid MP client from United Devices and adding support for Berkeley Open Infrastructure for Network Computing (BOINC) in 2005, World Community Grid eventually discontinued the Grid MP client and consolidated on the BOINC platform in 2008. In September 2021, it was announced that IBM transferred ownership to the Krembil Research Institute of University Health Network in Toronto, Ontario.
LHC@home is a volunteer computing project researching particle physics that uses the Berkeley Open Infrastructure for Network Computing (BOINC) platform. The project's computing power is utilized by physicists at CERN in support of the Large Hadron Collider and other experimental particle accelerators.
The Human Proteome Folding Project (HPF) is a collaborative effort between New York University, the Institute for Systems Biology (ISB) and the University of Washington, using the Rosetta software developed by the Rosetta Commons. The project is managed by the Bonneau lab.
United Devices, Inc. was a privately held, commercial volunteer computing company that focused on the use of grid computing to manage high-performance computing systems and enterprise cluster management. Its products and services allowed users to "allocate workloads to computers and devices throughout enterprises, aggregating computing power that would normally go unused." It operated under the name Univa UD for a time, after merging with Univa on September 17, 2007.
David Pope Anderson is an American research scientist at the Space Sciences Laboratory, at the University of California, Berkeley, and an adjunct professor of computer science at the University of Houston. Anderson leads the SETI@home, BOINC, Bossa, and Bolt software projects.
Rosetta@home is a volunteer computing project researching protein structure prediction on the Berkeley Open Infrastructure for Network Computing (BOINC) platform, run by the Baker lab. Rosetta@home aims to predict protein–protein docking and design new proteins with the help of about fifty-five thousand active volunteered computers processing at over 487,946 GigaFLOPS on average as of September 19, 2020. Foldit, a Rosetta@home videogame, aims to reach these goals with a crowdsourcing approach. Though much of the project is oriented toward basic research to improve the accuracy and robustness of proteomics methods, Rosetta@home also does applied research on malaria, Alzheimer's disease, and other pathologies.
SZTAKI Desktop Grid (SzDG) was a BOINC project located in Hungary run by the Computer and Automation Research Institute (SZTAKI) of the Hungarian Academy of Sciences. It closed on June 21, 2018.
Volunteer computing is a type of distributed computing in which people donate their computers' unused resources to a research-oriented project, and sometimes in exchange for credit points. The fundamental idea behind it is that a modern desktop computer is sufficiently powerful to perform billions of operations a second, but for most users only between 10–15% of its capacity is used. Common tasks such as word processing or web browsing leave the computer mostly idle.
Ibercivis was a volunteer computing platform which allows internet users to participate in scientific research by donating unused computer cycles to run scientific simulations and other tasks. The original project, which became operational in 2008, was a scientific collaboration between the Portuguese and Spanish governments, but it is open to the general public and scientific community, both within and beyond the Iberian Peninsula. The project's name is a portmanteau of Iberia and the Latin word civis, meaning 'citizen'.
GridRepublic is a BOINC Account Manager. It focuses on creating a clean and simple way to join and interact with BOINC. GridRepublic was started with a mission to raise public awareness and participation in volunteer computing with BOINC. GridRepublic was formed in 2004 by Matthew Blumberg as a mechanism to control the multiple projects from one place. The code for the BOINC software had to be redesigned to allow for the Account Manager system to be implemented.
POEM@Home was a volunteer computing project hosted by the Karlsruhe Institute of Technology and running on the Berkeley Open Infrastructure for Network Computing (BOINC) software platform. It modeled protein folding using Anfinsen's dogma. POEM@Home was started in 2007 and, due to advances using GPUs that rendered the BOINC program redundant, concluded in October 2016. The POEM@home applications were proprietary.
Smash Childhood Cancer is a World Community Grid volunteer computing subproject on the BOINC platform. It is based on World Community Grid's Help Childhood Cancer subproject which was a joint effort of Chiba University and the Chiba Cancer Center. Based on the results of that project, the Smash Childhood Cancer started in January 2017 looking for drug candidates targeting additional childhood cancers.
Help Cure Muscular Dystrophy is a volunteer computing project that runs on the BOINC platform.
Décrypthon is a project which uses grid computing resources to contribute to medical research. The word is a portmanteau of the French word "décrypter" and "telethon".
SLinCA@Home was a research project that uses Internet-connected computers to do research in fields such as physics and materials science.
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