Hydrogen dehydrogenase

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hydrogen dehydrogenase
Identifiers
EC no. 1.12.1.2
CAS no. 9027-05-8
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In enzymology, a hydrogen dehydrogenase (EC 1.12.1.2) is an enzyme that catalyzes the chemical reaction

H2 + NAD+ H+ + NADH

Thus, the two substrates of this enzyme are H2 and NAD+, whereas its two products are H+ and NADH.

This enzyme belongs to the family of oxidoreductases, specifically those acting on hydrogen as donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is hydrogen:NAD+ oxidoreductase. Other names in common use include H2:NAD+ oxidoreductase, NAD+-linked hydrogenase, bidirectional hydrogenase, and hydrogenase. This enzyme participates in glyoxylate and dicarboxylate metabolism and methane metabolism. It has 6 cofactors: FAD, Iron, FMN, Flavin, Nickel, and Iron-sulfur.

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References


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