| Name | Notability | References |
|---|
| John Abercrombie | U.S. Representative (1912–1917), president of the University of Alabama (1902–1911) | [56] |
| Winton M. Blount | United States Postmaster General (1969–1972) and philanthropist | [57] |
| Bobby Bright | Mayor (1999–2009), U.S. Representative (2009–2011) | [58] |
| Katie Britt | U.S. Senator (2023–present) | [59] |
| Charles Waldron Buckley | U.S. Representative (1868–1873) | [60] |
| Artur Davis | U.S. Representative (2003–2011) | [61] |
| William Louis Dickinson | U.S. Representative (1965–1993) | [62] |
| Edward C. Elmore | Confederate States of America treasurer | [63] |
| Benjamin Fitzpatrick | 11th Governor of Alabama (1841–1845); United States Senator (1848–9, 1953-5, 1855–61) and President pro tempore (1857–60) | [64] |
| Emory Folmar | Mayor (1977–1999) | [65] |
| Jim Folsom Jr. | 50th Governor of Alabama (1993–1995), Lieutenant Governor (1987–1993, 2007–2011) | [66] |
| MacDonald Gallion | Attorney General of Alabama (1953–63, 1967–71) | [67] |
| Bibb Graves | 38th Governor of Alabama (1927–1931, 1935–1939) | [68] |
| Dixie Bibb Graves | First female United States Senator from Alabama (1937–1938) | [69] |
| J. Lister Hill | U.S. Representative (1923–38), U.S. Senator (1938–69), Senate Majority Whip (1941–47), known for the Hill-Burton Act | [70] |
| Perry O. Hooper Jr. | Member of Alabama House of Representatives (1984–2003) | [71] |
| Perry O. Hooper Sr. | Alabama Supreme Court 27th chief justice (1995–2001) | [72] |
| Thomas G. Jones | 28th Governor of Alabama (1890–1894) | [73] |
| Claude R. Kirk Jr. | Governor of Florida (1967–1971) | [74] |
| Ann McCrory | First Lady of North Carolina |
| Gordon Persons | 46th Governor of Alabama (1951–1955) | [75] |
| Martha Roby | Congresswoman from Alabama's 2nd congressional district (2011-2021) | [76] |
| Joe M. Rodgers | Construction executive, United States Ambassador to France | [77] |
| Sylvia Swayne | First openly transgender woman to run for public office in Alabama | [78] |
| Dorothy Tillman | Former Chicago Alderman | [79] |
| Steve Windom | 28th Lieutenant Governor of Alabama (1999–2003) | [80] |
| William Lowndes Yancey | U.S. Representative (1844–46), Fire-Eater secession advocate, Confederate diplomat and Senator | [81] |