lysine-tRNA(Pyl) ligase | |||||||||
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Identifiers | |||||||||
EC no. | 6.1.1.25 | ||||||||
CAS no. | 782472-12-2 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a lysine-tRNAPyl ligase (EC 6.1.1.25) is an enzyme that catalyzes the chemical reaction
The 3 substrates of this enzyme are ATP, L-lysine, and tRNA(Pyl), whereas its 3 products are AMP, diphosphate, and L-lysyl-tRNA(Pyl).
This enzyme belongs to the family of ligases, to be specific those forming carbon-oxygen bonds in aminoacyl-tRNA and related compounds. The systematic name of this enzyme class is L-lysine:tRNAPyl ligase (AMP-forming).
Pyrrolysine is an α-amino acid that is used in the biosynthesis of proteins in some methanogenic archaea and bacteria; it is not present in humans. It contains an α-amino group, a carboxylic acid group. Its pyrroline side-chain is similar to that of lysine in being basic and positively charged at neutral pH.
In enzymology, an alanine—tRNA ligase is an enzyme that catalyzes the chemical reaction
In enzymology, an arginine—tRNA ligase is an enzyme that catalyzes the chemical reaction
In enzymology, an asparagine-tRNA ligase is an enzyme that catalyzes the chemical reaction
Aspartate—tRNAAsn ligase is an enzyme with systematic name L-aspartate:tRNAAsx ligase (AMP-forming). This enzyme catalyses the following chemical reaction
In enzymology, an aspartate—tRNA ligase is an enzyme that catalyzes the chemical reaction
In enzymology, a cysteine—tRNA ligase is an enzyme that catalyzes the chemical reaction
In enzymology, a glutamate—tRNAGln ligase is an enzyme that catalyzes the chemical reaction
In enzymology, a glutamate—tRNA ligase is an enzyme that catalyzes the chemical reaction
In enzymology, a glutamine—tRNA ligase is an enzyme that catalyzes the chemical reaction
In enzymology, a histidine-tRNA ligase is an enzyme that catalyzes the chemical reaction
In enzymology, a leucine—tRNA ligase is an enzyme that catalyzes the chemical reaction
In enzymology, a lysine—tRNA ligase is an enzyme that catalyzes the chemical reaction
In enzymology, a methionine—tRNA ligase is an enzyme that catalyzes the chemical reaction
In enzymology, a proline—tRNA ligase is an enzyme that catalyzes the chemical reaction
In enzymology, a serine—tRNA ligase is an enzyme that catalyzes the chemical reaction
In enzymology, a threonine-tRNA ligase is an enzyme that catalyzes the chemical reaction
In enzymology, a tryptophan-tRNA ligase is an enzyme that catalyzes the chemical reaction
Pyrrolysine—tRNAPyl ligase is an enzyme with systematic name L-pyrrolysine:tRNAPyl ligase (AMP-forming). This enzyme catalyses the following chemical reaction
TRNAIle-lysidine synthase (EC 6.3.4.19, TilS, mesJ (gene), yacA (gene), isoleucine-specific transfer ribonucleate lysidine synthetase, tRNAIle-lysidine synthetase) is an enzyme with systematic name L-lysine:(tRNAIle2)-cytidine34 ligase (AMP-forming). This enzyme catalyses the following chemical reaction