Provincial Trunk Highway 1 is Manitoba's section of the Trans-Canada Highway. It is a heavily used, 4-lane divided highway, with the exception of a short 18 km section in the southeastern corner of the province. It is the main link between southern Manitoba's largest cities, and also serves as the province's main transportation link to the neighbouring provinces of Saskatchewan and Ontario. The highway is the only major east-west divided highway in Manitoba, and carries a large majority of east-west traffic within and through the province. It has full freeway status sections at Portage la Prairie and Winnipeg. The total distance of the Trans-Canada Highway in Manitoba is approximately 490 km (300 mi).
Provincial Trunk Highway 75 is a major highway in the Canadian province of Manitoba. It is the main link between the city of Winnipeg and the United States border, where it connects with Interstate 29/U.S. Route 81.
Provincial Trunk Highway 16 (PTH 16) is a provincial highway in the Canadian province of Manitoba. It is the Manitoba section of the Yellowhead Highway, and also the Trans-Canada Highway Yellowhead section. The main purpose of this highway is to connect Winnipeg with other Canadian cities such as Saskatoon and Edmonton. The highway runs from Bloom at an intersection with the Trans-Canada Highway and Provincial Road 305 ten kilometres (6.2 mi) west of Portage la Prairie to the Saskatchewan boundary sixteen kilometres (9.9 mi) west of Russell, where it continues as Saskatchewan Highway 16.
Provincial Trunk Highway 4 is a provincial highway in the Canadian province of Manitoba. The highway connects the city of Selkirk to PTH 59, the main route to Grand Beach and cottage country on the east side of Lake Winnipeg.
Provincial Trunk Highway 6 is a provincial primary highway located in the Canadian province of Manitoba. It runs from the Perimeter Highway of Winnipeg to the Thompson south city limits. It is also the main highway connecting Winnipeg to northern Manitoba. The speed limit is 100 km/h. The route is also used to deliver nickel from the Thompson mine to the Royal Canadian Mint in Winnipeg. The section of highway between its southern terminus near Winnipeg and the second junction with PTH 68 near Eriksdale is part of the Northern Woods and Water Route. The portion of the highway between Ponton and Thompson was known as Highway 391 prior to 1986.
Provincial Trunk Highway 9 is a provincial primary highway located in the Canadian province of Manitoba. It runs from Winnipeg north to Gimli.
Provincial Trunk Highway 16A is a provincial highway in the Canadian province of Manitoba which provides access to the town of Minnedosa. The highway is an alternate route of PTH 16 and PTH 10. Like most alternate routes, it previously served as the main highway through the town.
Provincial Trunk Highway 3A is a provincial primary highway located in the Canadian province of Manitoba. It runs from PTH 3 to the same route concurrent with PTH 34. The highway continues as PR 423 from its eastern terminus.
Provincial Trunk Highway 10 is a provincial primary highway located in the Canadian province of Manitoba.
Provincial Trunk Highway 44 is a provincial highway in the Canadian province of Manitoba.
Provincial Trunk Highway 13 is a provincial highway in the Canadian province of Manitoba. It is an RTAC route capable of handling RTAC vehicles such as trucks, truck and pony trailers, trucks and full trailers, truck tractors and semi-trailers, A-trains, B-trains, or C-trains. The route extends south to north from its junction with PTH 3 and PR 245 in Carman to its junction with PTH 1 and PR 430 north of Oakville. The northern terminus of PTH 13 is located between Portage la Prairie and Manitoba's capital city Winnipeg. The Central Manitoba Railway (CEMR) shortline rail intersects PTH 13 north of Carman, the Canadian Pacific Railway (CPR) intersects at Elm Creek, and the Canadian National Railway (CNR) at Oakville.
Provincial Trunk Highway 25 is a provincial highway in the Canadian province of Manitoba. It is a short east-west route starting at PR 259 at Wheatland, east through Rivers, and terminating at PTH 10 six kilometres (3.7 mi) north of Forrest. PTH 25 serves as the major route, via PTH 10, between Rivers and Brandon.
Provincial Trunk Highway 45 is a provincial highway in the southwest region of the Canadian province of Manitoba. It runs from PTH 16 and PTH 83 in the town of Russell to PTH 10 five kilometres (3.1 mi) north of the village of Erickson.
Provincial Trunk Highway 42 is a short provincial highway in the southwest region of the Canadian province of Manitoba. It runs from PTH 16 in the town of Shoal Lake to PTH 41 just east of the French-speaking village of St. Lazare.
Provincial Trunk Highway 20 is a provincial highway in the Canadian province of Manitoba. It runs from PTH 5 and PR 582 just south of Ochre River to PTH 10 in the village of Cowan. The highway provides an eastern alternative access option to Dauphin along with PTH 20A.
Provincial Trunk Highway 26 is a provincial highway in the Canadian province of Manitoba. It is an east-west route that begins and ends at the Trans-Canada Highway. The western terminus is located near the interchange of PTH 1 and PTH 1A approximately 3 kilometres east of Portage la Prairie, while the eastern terminus is 3 kilometres southeast of St. François Xavier and 13 kilometres west of Winnipeg's Perimeter Highway. PTH 26 provides access to the small communities of St. François Xavier and Poplar Point. It serves as an alternative scenic route between Portage la Prairie and Winnipeg as it closely follows the Assiniboine River which flows south of the highway. The speed limit on this highway is 90 kilometres per hour (56 mph).
Provincial Trunk Highway 67 is a short provincial highway in the Canadian province of Manitoba. It runs as an east-west route just north of Winnipeg city limits between PTH 6 near the village of Warren to PTH 9 at the gate to Lower Fort Garry.
Manitoba Provincial Road 344 is a very short provincial road in the Canadian province of Manitoba.
Manitoba Provincial Road 331 is an east-west provincial road in the south-central section of the Canadian province of Manitoba.
Provincial Road 482 is provincial road in the far western part of the Canadian province of Manitoba.
PTH 1 (TCH) west of Portage la Prairie 
PR 240 north (Tupper Street N.)
PTH 10 (18th Street)
PR 457 east (Veterans Way)
