Provincial Trunk Highway 1 is Manitoba's section of the Trans-Canada Highway. It is a heavily used, 4-lane divided highway, with the exception of a short 18 km section in the southeastern corner of the province. It is the main link between southern Manitoba's largest cities, and also serves as the province's main transportation link to the neighbouring provinces of Saskatchewan and Ontario. The highway is the only major east-west divided highway in Manitoba, and carries a large majority of east-west traffic within and through the province. It has full freeway status sections at Portage la Prairie and Winnipeg. The total distance of the Trans-Canada Highway in Manitoba is approximately 490 km (300 mi).
Provincial Trunk Highway 4 is a provincial highway in the Canadian province of Manitoba. The highway connects the city of Selkirk to PTH 59, the main route to Grand Beach and cottage country on the east side of Lake Winnipeg.
Provincial Trunk Highway 6 is a provincial primary highway located in the Canadian province of Manitoba. It runs from the Perimeter Highway of Winnipeg to the Thompson south city limits. It is also the main highway connecting Winnipeg to northern Manitoba. The speed limit is 100 km/h. The route is also used to deliver nickel from the Thompson mine to the Royal Canadian Mint in Winnipeg. The section of highway between its southern terminus near Winnipeg and the second junction with PTH 68 near Eriksdale is part of the Northern Woods and Water Route. The portion of the highway between Ponton and Thompson was known as Highway 391 prior to 1986.
Provincial Trunk Highway 17 is a provincial highway in the Interlake Region of the Canadian province of Manitoba. It runs from a junction with PR 224 and PR 325 near Hodgson to a junction with PTH 9 near Winnipeg Beach.
Provincial Trunk Highway 11 (PTH 11) is a provincial primary highway located in the Eastman Region of the Canadian province of Manitoba. It runs from an intersection with PTH 59 near Victoria Beach to an intersection with PTH 1.
Provincial Trunk Highway 5 is a provincial primary highway located in the Canadian province of Manitoba.
Provincial Trunk Highway 23 is a major east-west provincial highway in the southern portion of the Canadian province of Manitoba. It runs from PTH 21 just south of Hartney to PTH 59 in La Rochelle. Along its route, PTH 23 passes through the communities of Elgin, Ninette, Baldur, Miami, Lowe Farm, and Morris.
Provincial Trunk Highway 45 is a provincial highway in the Parkland Region of the Canadian province of Manitoba. It runs from PTH 16 and PTH 83 in the town of Russell to PTH 10 five kilometres (3.1 mi) north of the village of Erickson.
Provincial Trunk Highway 42 is a short provincial highway in the southwest region of the Canadian province of Manitoba. It runs from PTH 16 in the town of Shoal Lake to PTH 41 just east of the French-speaking village of St. Lazare.
Provincial Trunk Highway 41 is a short provincial highway in the far southwest region of the Canadian province of Manitoba. It runs from PTH 1 and PR 542 in the village of Kirkella to PTH 16 and PTH 83 just south of Binscarth.
Provincial Trunk Highway 21 is a provincial highway in the Canadian province of Manitoba. It runs from the U.S. border to PTH 45 and PR 577 in the village of Oakburn.
Provincial Trunk Highway 26, also known as Chemin Assiniboine Trail, is a provincial highway in the Canadian province of Manitoba. It is an east-west route that begins and ends at the Trans-Canada Highway. The western terminus is located near the interchange of PTH 1 and PTH 1A approximately 3 kilometres east of Portage la Prairie, while the eastern terminus is 3 kilometres southeast of St. François Xavier and 13 kilometres west of Winnipeg's Perimeter Highway. PTH 26 provides access to the small communities of St. François Xavier and Poplar Point. It serves as an alternative scenic route between Portage la Prairie and Winnipeg as it closely follows the Assiniboine River which flows south of the highway. The speed limit on this highway is 90 kilometres per hour (56 mph).
Provincial Trunk Highway 34 is a provincial primary highway located in the Canadian province of Manitoba. It runs from the U.S. border to PTH 16 at the town of Gladstone.
Provincial Road 242 is a north-south provincial road in the Pembina Valley and Central Plains Regions of Manitoba, Canada.
Provincial Road 240 (PR 240) is a 122.8-kilometre-long (76.3 mi) north–south highway in the Pembina Valley and Central Plains regions of Manitoba, connecting the hamlets of Darlingford, Miami, Roseisle, and St. Claude with the city of Portage la Prairie, as well as providing the only road access to the hamlet of Delta Beach on Lake Manitoba.
Provincial Road 260 is a 40.9-kilometre-long (25.4 mi) north–south highway in the Central Plains Region of Manitoba. It connects the communities of Gladstone and Keyes with Ogilvie, Plumas, Waldersee, Tenby, and via PR 261, Amaranth and the western shore of Lake Manitoba.
Provincial Road 264 is a 119.2-kilometre-long (74.1 mi) north–south highway in the Westman and Parkland Regions of Manitoba, connecting Crandall, Decker, Kelloe, Rossburn, and Silver Beach.
Provincial Road 265 is a 80.6-kilometre-long (50.1 mi) east–west road in the Westman and Central Plains Regions of Manitoba. Mostly a gravel road, it connects the communities of Clanwilliam, Polonia, Eden, Plumas, and Langruth, as well as providing a connection between Riding Mountain National Park and Lake Manitoba.
Provincial Road 278 (PR 278) is a 41.8-kilometre-long (26.0 mi) north–south highway in the Rural Municipality of Alonsa, Manitoba. Running along the western coastlines of both Lake Manitoba and Ebb and Flow Lake, it serves as the only road access to the Ebb and Flow First Nation, as well as connecting Kinosota, Bacon Ridge, Eddystone, Reedy Creek, and Silver Ridge. Margaret Bruce Provincial Park can also be accessed from the highway.
Provincial Road 430 is a 38.8-kilometre-long (24.1 mi) north–south highway in the Central Plains Region of Manitoba. Serving as a northern continuation of PTH 13, it provides road access to the town of St. Ambroise and St. Ambroise Beach Provincial Park on the southern shores of Lake Manitoba.
PTH 5 / PR 361 at McCreary 
PTH 16 (TCH) / YH near Westbourne 
