Provincial Trunk Highway 1 is Manitoba's section of the Trans-Canada Highway. It is a heavily used, 4-lane divided highway, with the exception of a short 18 km section in the southeastern corner of the province. It is the main link between southern Manitoba's largest cities, and also serves as the province's main transportation link to the neighbouring provinces of Saskatchewan and Ontario. The highway is the only major east-west divided highway in Manitoba, and carries a large majority of east-west traffic within and through the province. It has full freeway status sections at Portage la Prairie and Winnipeg. The total distance of the Trans-Canada Highway in Manitoba is approximately 490 km (300 mi).
Provincial Trunk Highway 6 is a provincial primary highway located in the Canadian province of Manitoba. It runs from the Perimeter Highway of Winnipeg to the Thompson south city limits. It is also the main highway connecting Winnipeg to northern Manitoba. The speed limit is 100 km/h. The route is also used to deliver nickel from the Thompson mine to the Royal Canadian Mint in Winnipeg. The section of highway between its southern terminus near Winnipeg and the second junction with PTH 68 near Eriksdale is part of the Northern Woods and Water Route. The portion of the highway between Ponton and Thompson was known as Highway 391 prior to 1986.
Provincial Trunk Highway 2 is a 315-kilometre (196-mile) highway in the Canadian province of Manitoba. It runs from Highway 13 at the Manitoba-Saskatchewan border to Winnipeg's Perimeter Highway near Oak Bluff.
Provincial Trunk Highway 60 is a provincial highway in the Canadian province of Manitoba. It runs from PTH 10 to PTH 6. Much of its length runs adjacent to the north shore of Lake Winnipegosis.
Provincial Trunk Highway 3 (PTH 3) is a major provincial highway located in the Canadian province of Manitoba. It runs from the Saskatchewan boundary to the southwest city limits of Winnipeg, where it continues as Winnipeg Route 155. Prior before to the implementation of Winnipeg's City Route System, it extended to Pembina Highway.
Provincial Trunk Highway 39 is a provincial highway in the Canadian province of Manitoba. It runs from PTH 6 to PTH 10.
Provincial Trunk Highway 17 is a provincial highway in the Interlake Region of the Canadian province of Manitoba. It runs from a junction with PR 224 and PR 325 near Hodgson to a junction with PTH 9 near Winnipeg Beach.
Provincial Trunk Highway 11 (PTH 11) is a provincial primary highway located in the Eastman Region of the Canadian province of Manitoba. It runs from an intersection with PTH 59 near Victoria Beach to an intersection with PTH 1.
Provincial Trunk Highway 32 is a provincial primary highway located in the Canadian province of Manitoba. It runs from PTH 14 at Winkler to the U.S. border, where it becomes North Dakota State Highway 32. Between its northern end and its intersection with PR 243, PTH 32 follows the Boundary Commission Trail.
Provincial Trunk Highway 5 is a provincial primary highway located in the Canadian province of Manitoba.
The Northern Woods and Water Route is a 2,400-kilometre (1,500 mi) route through northern British Columbia, Alberta, Saskatchewan and Manitoba in Western Canada. As early as the 1950s, community groups came together to establish a northern travel route; this was proposed as the Northern Yellowhead Transportation Route. The Northern Woods and Water Route Association was established in 1974, and encouraged promotion of the route with the promise of an increase in tourist travel. The route was designated in 1974 and is well signed throughout its component highways. The route starts at Dawson Creek as the Spirit River Highway and ends at the Perimeter of Winnipeg, Manitoba, after running through the northern regions of the western provinces. From west to east, the Northern Woods and Water Route (NWWR) incorporates portions of British Columbia Highway 49; Alberta Highways 49, 2A, 2, & 55; Saskatchewan Highways 55 & 9; Manitoba Provincial Road 283 and Trunk Highways 10, 5, 68 & 6. The halfway point of the NWWR is approximately at Goodsoil, Saskatchewan.
Provincial Trunk Highway 10 is a provincial primary highway located in the Canadian province of Manitoba.
Highway 10 is a provincial paved undivided highway in the Canadian province of Saskatchewan. It runs from Highway 1 near Balgonie until it transitions into PTH 5 at the Manitoba border. Highway 10 is about 225 km (140 mi) long. It passes through Fort Qu'Appelle, Balcarres, Melville, and Yorkton. It intersects Highway 1 and Highway 16.
Highway 49 and Provincial Trunk Highway 49 is a provincial highway in the Canadian provinces of Saskatchewan and Manitoba. Most of the highway is in the east-central part of Saskatchewan and only a very short section is in Manitoba. It runs from Saskatchewan Highway 35 between the communities of Fosston and Hendon to the Saskatchewan — Manitoba border, before ending at Provincial Trunk Highway 83 south of the community of Benito. The combined highway is about 166.4 kilometres (103.4 mi) in length — 165.2 kilometres (102.7 mi) is in Saskatchewan and 1.2 kilometres (0.7 mi) is in Manitoba.
Provincial Road 283 is a provincial road in Manitoba, Canada which succeeds Saskatchewan Highway 9 at the Saskatchewan provincial boundary and terminates at Manitoba Highway PTH 10 in The Pas.
Provincial Trunk Highway 22 is a short north-south provincial highway in the Canadian province of Manitoba. It runs from PTH 23 near Elgin to PTH 2 and PR 250 in Souris. This highway is the main access road to the renowned Souris Swinging Bridge.
Provincial Trunk Highway 25 is a provincial highway in the Canadian province of Manitoba. It is a short east-west route starting at PR 259 at Wheatland, east through Rivers, and terminating at PTH 10 six kilometres (3.7 mi) north of Forrest. PTH 25 serves as the major route, via PTH 10, between Rivers and Brandon.
Provincial Trunk Highway 50 is a provincial highway in the south-central region of the Canadian province of Manitoba. It runs from PTH 16 to PTH 5 and PR 361 in the village of McCreary.
Provincial Trunk Highway 41 is a short provincial highway in the far southwest region of the Canadian province of Manitoba. It runs from PTH 1 and PR 542 in the village of Kirkella to PTH 16 and PTH 83 just south of Binscarth.
Provincial Trunk Highway 21 is a provincial highway in the Canadian province of Manitoba. It runs from the U.S. border to PTH 45 and PR 577 in the village of Oakburn.
Highway 3 at Saskatchewan border near Westgate 
PTH 10 near Baden 
