Marcus Raichle

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Marcus Raichle
Marcus Raichle in 2014
Born (1937-03-15) March 15, 1937 (age 81)
Known for default mode, functional neuroimaging
Awards Grawemeyer Award in Psychology (2001)
Kavli Prize in Neuroscience (2014)
Scientific career
Fields Neuroimaging
Institutions Washington University in St. Louis

Marcus E. Raichle (born March 15, 1937) is an American neurologist at the Washington University School of Medicine in Saint Louis, Missouri. He is a professor in the Department of Radiology with joint appointments in Neurology, Neurobiology and Biomedical Engineering. His research over the past 40 years has focused on the nature of functional brain imaging signals arising from PET and fMRI and the application of these techniques to the study of the human brain in health and disease. [1] He received the Kavli Prize in Neuroscience “for the discovery of specialized brain networks for memory and cognition", together with Brenda Milner and John O’Keefe in 2014.

Contents

Career

Noteworthy accomplishments of Marcus Raichle include the discovery of the relative independence of blood flow and oxygen consumption during changes in brain activity which provided the physiological basis of fMRI; [2] the discovery of a default mode of brain function (i.e., organized intrinsic activity) and its signature system, [3] the brain’s default mode network; [4] and, the discovery that aerobic glycolysis contributes to brain function independent of oxidative phosphorylation. [5] [6]

Honors

Awards

In 2001, he was a co-recipient of Grawemeyer Award in Psychology, with Michael Posner and Steven Petersen of the University of Louisville. [7] In 2010, he was awarded the Ariëns Kappers Medal from the Royal Netherlands Academy of Arts and Sciences. In 2014, he was a co-recipient of the Kavli Prize in Neuroscience, awarded by the Norwegian Academy of Science and Letters, with Brenda Milner of the Montreal Neurological Institute at McGill University and John O’Keefe of University College London. [8]

Selected publications

References

  1. "Academy Members". academyofsciencestl.org. Archived from the original on October 8, 2011.
  2. Petersen, SE; Fox PT; Posner MI; Mintun M; Raichle ME (1988). "Positron emission tomographic studies of the cortical anatomy of single-word processing". Nature. 331 (6157): 585–589. doi:10.1038/331585a0. PMID   3277066.
  3. Raichle, M. E.; MacLeod, A. M.; Snyder, A. Z.; Powers, W. J.; Gusnard, D. A.; Shulman, G. L. (2001-01-16). "A default mode of brain function". Proceedings of the National Academy of Sciences of the United States of America. 98 (2): 676–682. doi:10.1073/pnas.98.2.676. ISSN   0027-8424. PMC   14647 . PMID   11209064.
  4. Fox, MD; Zhang D; Snyder DZ; Raichle ME (2009). "The global signal and observed anticorrelated resting state brain networks". J. Neurophysiol. 101 (6): 3270–3283. doi:10.1152/jn.90777.2008. PMC   2694109 . PMID   19339462.
  5. Vaishnavi, SN; Vlassenko AG; Rundle MM; Snyder AZ; Mintun MA; Raichle ME (2010). "Regional aerobic glycolysis in the human brain". PNAS. 107 (41): 17757–17762. doi:10.1073/pnas.1010459107. PMC   2955101 . PMID   20837536.
  6. Vlassenko AG, Vaishnavi SN, Couture L, Sacco D, Shannon BJ, Mac, RH, Morris JC, Raichle ME, Mintun MA (2010). "Spatial correlation between brain aerobic glycolysis and amyloid-β deposition". PNAS. 107 (41): 17763–17767. doi:10.1073/pnas.1010461107. PMC   2955133 . PMID   20837517.
  7. "2001– Michael Posner, Marcus Raichle and Steven Petersen". grawemeyer.org. Archived from the original on May 21, 2014.
  8. Bhattacharjee, Yudhijit (May 29, 2014). "Nine Scientists Share Three Kavli Prizes".