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An inverted microscope is a microscope with its light source and condenser on the top, above the stage pointing down, while the objectives and turret are below the stage pointing up. It was invented in 1850 by J. Lawrence Smith, a faculty member of Tulane University.
Tuberculosis is diagnosed by finding Mycobacterium tuberculosis bacteria in a clinical specimen taken from the patient. While other investigations may strongly suggest tuberculosis as the diagnosis, they cannot confirm it.
Tuberculosis management describes the techniques and procedures utilized in treating tuberculosis (TB).
Cayetano Heredia University is a private nonprofit university located in Lima, Peru. It was named in honor of Cayetano Heredia, one of the eminent Peruvian physicians of the 19th century. The university is overseen by a board of trustees (patronato) and is not owned by any private or state entity. It is considered one of the top medical schools in Peru, along the Faculty of Medicine "San Fernando" of National University of San Marcos, and is currently one of the major producers and publishers of scientific research in the country.
Humberto Guerra Allison, is a physician and scientist. He graduated from Universidad Peruana Cayetano Heredia (MD) and Baylor College of Medicine. With Hugo Lumbreras, he co-founded a Tropical Medicine Institute at Cayetano Heredia University, the Instituto de Medicina Tropical Alexander von Humboldt at Lima, Peru. Guerra later directed the Institute.
In microbiology, the minimum inhibitory concentration (MIC) is the lowest concentration of a chemical, usually a drug, which prevents visible growth of a bacterium or bacteria. MIC depends on the microorganism, the affected human being, and the antibiotic itself. It is often expressed in micrograms per milliliter (μg/mL) or milligrams per liter (mg/L).
The disk diffusion test is a culture-based microbiology assay used in diagnostic and drug discovery laboratories. In diagnostic labs, the assay is used to determine the susceptibility of bacteria isolated from a patient's infection to clinically approved antibiotics. This allows physicians to prescribe the most appropriate antibiotic treatment. In drug discovery labs, especially bioprospecting labs, the assay is used to screen biological material and drug candidates for antibacterial activity. When bioprospecting, the assay can be performed with paired strains of bacteria to achieve dereplication and provisionally identify antibacterial mechanism of action.
Mycobacterium fortuitum is a nontuberculous species of the phylum Actinomycetota, belonging to the genus Mycobacterium.
Extensively drug-resistant tuberculosis (XDR-TB) is a form of tuberculosis caused by bacteria that are resistant to some of the most effective anti-TB drugs. XDR-TB strains have arisen after the mismanagement of individuals with multidrug-resistant TB (MDR-TB).
The National Tuberculosis Elimination Program (NTEP) is the Public Health initiative of the Government of India that organizes its anti-Tuberculosis efforts. It functions as a flagship component of the National Health Mission (NHM) and provides technical and managerial leadership to anti-tuberculosis activities in the country. As per the National Strategic Plan 2017–25, the program has a vision of achieving a "TB free India",with a strategies under the broad themes of "Prevent, Detect,Treat and Build pillars for universal coverage and social protection". The program provides, various free of cost, quality tuberculosis diagnosis and treatment services across the country through the government health system.
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The Xpert MTB/RIF is a cartridge-based nucleic acid amplification test (NAAT) for simultaneous rapid tuberculosis diagnosis and rapid antibiotic sensitivity test. It is an automated diagnostic test that can identify Mycobacterium tuberculosis (MTB) DNA and resistance to rifampicin (RIF). It was co-developed by the laboratory of Professor David Alland at the University of Medicine and Dentistry of New Jersey (UMDNJ), Cepheid Inc. and Foundation for Innovative New Diagnostics, with additional financial support from the US National Institutes of Health (NIH).
The Iquitos Satellite Laboratory (IQTLAB) was established in 2002 in the city of Iquitos, Peru by doctor Margaret Kosek, biologist Maribel Paredes Olortegui, and nurse Pablo Peñataro Yori, with the collaboration of the Dr. Robert Gilman working group in Lima, Peru and the US Naval Medical Research Unit No. 6 (NAMRU-6).
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Javier Mariátegui Chiappe was a renowned Peruvian intellectual and psychiatrist. He was the last of the children of José Carlos Mariátegui and Anna Chiappe. Studied at the University of San Marcos where he also started teaching; he was also a founder of Cayetano Heredia University. He was also the founding director of the National Institute of Mental Health “Honorio Delgado - Hideyo Noguchi”. He died in Lima.
Tuberculosis in India is a major health problem, causing about 220,000 deaths every year. In 2020, the Indian government made statements to eliminate tuberculosis from the country by 2025 through its National TB Elimination Program. Interventions in this program include major investment in health care, providing supplemental nutrition credit through the Nikshay Poshan Yojana, organizing a national epidemiological survey for tuberculosis, and organizing a national campaign to tie together the Indian government and private health infrastructure for the goal of eliminating the disease.
The National Tuberculosis Institute is a Government of India institute, under the Directorate General of Health Services, Ministry of Health and Family Welfare, dedicated to advanced research on Tuberculosis. The Institute is located along Bellary Road, in Bengaluru, Karnataka state, India.
Ramiro Castro de la Mata was a physician, scientist, pharmacologist, professor and founder of the University Cayetano Heredia in Lima, Peru. He was recognized internationally as an expert in drug addiction.
Dionicia Gamboa is a Peruvian parasitologist and professor at Institute of Tropical Medicine Alexander von Humboldt, Cayetano Heredia University. Her research focusses on Plasmodium vivax, a major malaria parasite species in South America.
Patricia Jannet García Funegra is a Peruvian professor of public and global health at Cayetano Heredia University. She originally trained as a clinician before focusing on research and public health. Her work also focuses on reproductive health, sexually transmitted diseases, and medical informatics. In 2016-17 García was the Minister of Health of Peru. She was the first Peruvian to be elected to the US National Academy of Medicine in 2016.
References
- ↑ Minion J, Leung E, Menzies D, Pai M (2010). "Microscopic-observation drug susceptibility and thin layer agar assays for the detection of drug resistant tuberculosis: a systematic review and meta-analysis". Lancet Infect Dis. 10 (10): 688–698. doi:10.1016/S1473-3099(10)70165-1. PMID 20813587.
