| Portrait | Name
(Birth–Death)
Constituency | Political party | Title | Took office | Left office | Deputy Minister | Prime Minister
(Cabinet) |
|---|
| | Ong Kee Hui
(1914–2000)
MP for Bandar Kuching | Alliance (SUPP) | Minister of Technology, Research and Local Government | 1970 | 1972 | Vacant | Abdul Razak Hussein
(I) |
|---|
|  | Lee San Choon
(1935–2023)
MP for Segamat Selatan | Alliance (MCA) | Minister of Technology, Research and Coordination of New Villages | 1972 | 1974 | Abdul Razak Hussein
(I) |
|---|
| | Mohamed Yaacob
(1926–2009)
MP for Tanah Merah | BN (UMNO) | Minister of Energy, Technology and Research | 1974 | 1976 | Abdul Razak Hussein
(II) |
|---|
| | Ong Kee Hui
(1914–2000)
MP for Bandar Kuching | BN (SUPP) | Minister of Science, Technology and Environment | 1976 | 1982 | Abdullah Ahmad
(1976–1978)
Vacant
(1978–1979)
Clarence Elong Mansul
(1979–1981)
Vacant
(1981–1982) | Hussein Onn
(I · II)
Mahathir Mohamad
(I) |
|---|
| | Stephen Yong Kuet Tze
(1921–2001)
MP for Padawan | 1982 | 26 October 1990 | Vacant
(1982–1987)
Law Hieng Ding
(1979–1980) | Mahathir Mohamad
(II · III) |
|---|
| | Law Hieng Ding
(1935–2018)
MP for Sarikei | 27 October 1990 | 26 March 2004 | Peter Chin Fah Kui
(1990–1995)
Abu Bakar Daud
(1995–1999)
Zainal Dahlan
(1999–2004) | Mahathir Mohamad
(IV · V · VI)
Abdullah Ahmad Badawi
(I) |
|---|
|  | Jamaluddin Jarjis
(1951–2015)
MP for Rompin | BN (UMNO) | Minister of Science, Technology and Innovation | 27 March 2004 | 18 March 2008 | Kong Cho Ha | Abdullah Ahmad Badawi
(II) |
|---|
|  | Maximus Ongkili
(b. 1953)
MP for Kota Marudu | BN (PBS) | 19 March 2008 | 15 May 2013 | Fadillah Yusof | Abdullah Ahmad Badawi
(III)
Najib Razak
(I) |
|---|
| | Ewon Ebin
(b. 1954)
MP for Ranau | BN (UPKO) | 16 May 2013 | 29 July 2015 | Abu Bakar Mohamad Diah | Najib Razak
(II) |
|---|
| | Wilfred Madius Tangau
(b. 1958)
MP for Tuaran | 29 July 2015 | 9 May 2018 |
|---|
|  | Yeo Bee Yin
(b. 1983)
MP for Bakri | PH (DAP) | Minister of Energy, Science, Technology, Environment and Climate Change | 2 July 2018 | 24 February 2020 | Isnaraissah Munirah Majilis | Mahathir Mohamad
(VII) |
|---|
|  | Khairy Jamaluddin
(b. 1976)
MP for Rembau | BN (UMNO) | Minister of Science, Technology and Innovation | 10 March 2020 | 16 August 2021 | Ahmad Amzad Hashim | Muhyiddin Yassin
(I) |
|---|
|  | Adham Baba
(b.1962)
MP for Tenggara | BN (UMNO) | 30 August 2021 | 24 November 2022 | Ismail Sabri Yaakob
(I) |
|---|
|  | Chang Lih Kang
(b. 1980)
MP for Tanjong Malim | PH (PKR) | 3 December 2022 | Incumbent | Arthur Joseph Kurup
(2022–2023)
Yusof Apdal
(2023–current) | Anwar Ibrahim
(I) |
|---|
|
