NADPH dehydrogenase (quinone)

Last updated
NADPH dehydrogenase (quinone)
Identifiers
EC no. 1.6.5.10
CAS no. 37256-37-4
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
Search
PMC articles
PubMed articles
NCBI proteins

In enzymology, a NADPH dehydrogenase (quinone) (EC 1.6.5.10) is an enzyme that catalyzes the chemical reaction

Contents

NADPH + H+ + acceptor NADP+ + reduced acceptor

The 3 substrates of this enzyme are NADPH, H+, and acceptor, whereas its two products are NADP+ and reduced acceptor.

This enzyme belongs to the family of oxidoreductases, specifically those acting on NADH or NADPH with other acceptors. The systematic name of this enzyme class is NADPH:(quinone-acceptor) oxidoreductase. Other names in common use include reduced nicotinamide adenine dinucleotide phosphate (quinone), dehydrogenase, NADPH oxidase, and NADPH2 dehydrogenase (quinone). It has 2 cofactors: FAD, and Flavoprotein. Several compounds are known to inhibit this enzyme, including Folate, and Dicumarol.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1F5V.

See also

Related Research Articles

A dehydrogenase is an enzyme belonging to the group of oxidoreductases that oxidizes a substrate by reducing an electron acceptor, usually NAD+/NADP+ or a flavin coenzyme such as FAD or FMN. Like all catalysts, they catalyze reverse as well as forward reactions, and in some cases this has physiological significance: for example, alcohol dehydrogenase catalyzes the oxidation of ethanol to acetaldehyde in animals, but in yeast it catalyzes the production of ethanol from acetaldehyde.

<span class="mw-page-title-main">Shikimate dehydrogenase</span> Enzyme involved in amino acid biosynthesis

In enzymology, a shikimate dehydrogenase (EC 1.1.1.25) is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">Acetoacetyl-CoA reductase</span> InterPro Family

In enzymology, an acetoacetyl-CoA reductase (EC 1.1.1.36) is an enzyme that catalyzes the chemical reaction

In enzymology, an aryl-alcohol dehydrogenase (NADP+) (EC 1.1.1.91) is an enzyme that catalyzes the chemical reaction

In enzymology, a D-xylose 1-dehydrogenase (NADP+) (EC 1.1.1.179) is an enzyme that catalyzes the chemical reaction

In enzymology, a fructose 5-dehydrogenase (NADP+) (EC 1.1.1.124) is an enzyme that catalyzes the chemical reaction

In enzymology, a glycerol 2-dehydrogenase (NADP+) (EC 1.1.1.156) is an enzyme that catalyzes the chemical reaction

In enzymology, a glycerol-3-phosphate 1-dehydrogenase (NADP+) (EC 1.1.1.177) is an enzyme that catalyzes the chemical reaction

In enzymology, a lactaldehyde reductase (NADPH) (EC 1.1.1.55) is an enzyme that catalyzes the chemical reaction

In enzymology, a L-xylose 1-dehydrogenase (EC 1.1.1.113) is an enzyme that catalyzes the chemical reaction

Malate dehydrogenase (NADP<sup>+</sup>)

In enzymology, a malate dehydrogenase (NADP+) (EC 1.1.1.82) is an enzyme that catalyzes the chemical reaction

In enzymology, a sorbose 5-dehydrogenase (NADP+) (EC 1.1.1.123) is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">3-Hydroxybutyryl-CoA dehydrogenase</span> Class of enzymes

In enzymology, a 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157) is an enzyme that catalyzes the chemical reaction

In enzymology, an enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) (EC 1.3.1.39) is an enzyme that catalyzes the chemical reaction

In enzymology, an orotate reductase (NADPH) (EC 1.3.1.15) is an enzyme that catalyzes the chemical reaction

In enzymology, a hydrogen dehydrogenase (NADP+) (EC 1.12.1.3) is an enzyme that catalyzes the chemical reaction

In enzymology, a formyltetrahydrofolate dehydrogenase (EC 1.5.1.6) is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">NADPH dehydrogenase</span>

In enzymology, a NADPH dehydrogenase (EC 1.6.99.1) is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">NAD(P)H dehydrogenase (quinone)</span>

In enzymology, a NAD(P)H dehydrogenase (quinone) (EC 1.6.5.2) is an enzyme that catalyzes the chemical reaction

In enzymology, a NADPH:quinone reductase (EC 1.6.5.5) is an enzyme that catalyzes the chemical reaction

References


    This page is based on this Wikipedia article
    Text is available under the CC BY-SA 4.0 license; additional terms may apply.
    Images, videos and audio are available under their respective licenses.