Putrescine oxidase

putrescine oxidase
Identifiers
EC no.	1.4.3.10
CAS no.	9076-87-3
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, a putrescine oxidase (EC 1.4.3.10) is an enzyme that catalyzes the chemical reaction

putrescine + O₂ + H₂O ⇌ 4-aminobutanal + NH₃ + H₂O₂

The 3 substrates of this enzyme are putrescine, O₂, and H₂O, whereas its 3 products are 4-aminobutanal, NH₃, and H₂O₂.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH₂ group of donors with oxygen as acceptor. The systematic name of this enzyme class is putrescine:oxygen oxidoreductase (deaminating). This enzyme participates in urea cycle and metabolism of amino groups. It employs one cofactor, FAD.

References

• DeSa RJ (September 1972). "Putrescine oxidase from Micrococcus rubens. Purification and properties of the enzyme". The Journal of Biological Chemistry. 247 (17): 5527–34. doi: 10.1016/S0021-9258(20)81137-5 . PMID   4341347.
• Yamada H (1971). "Putrescine oxidase (Micrococcus rubens)". Metabolism of Amino Acids and Amines Part B. Methods Enzymol. Vol. 17B. pp. 726–730. doi:10.1016/0076-6879(71)17126-1. ISBN   978-0-12-181877-7.