TRNA (guanine26-N2)-dimethyltransferase

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TRNA (guanine26-N2)-dimethyltransferase
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EC no. 2.1.1.216
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TRNA (guanine26-N2)-dimethyltransferase (EC 2.1.1.216, Trm1p, TRM1, tRNA (m22G26)dimethyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (guanine26-N2)-dimethyltransferase. [1] [2] [3] [4] This enzyme catalyses the following chemical reaction

2 S-adenosyl-L-methionine + guanine 26 in tRNA 2 S-adenosyl-L-homocysteine + N2-dimethylguanine26 in tRNA

The enzyme dissociates from its tRNA substrate between the two consecutive methylation reactions.

Related Research Articles

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In enzymology, a tRNA (guanine-N1-)-methyltransferase (EC 2.1.1.31) is an enzyme that catalyzes the chemical reaction

In enzymology, a tRNA (guanine-N2-)-methyltransferase (EC 2.1.1.32) is an enzyme that catalyzes the chemical reaction

16S rRNA (guanine1207-N2)-methyltransferase (EC 2.1.1.172, m2G1207 methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:16S rRNA (guanine1207-N2)-methyltransferase. This enzyme catalyses the following chemical reaction

23S rRNA (adenine2503-C2,C8)-dimethyltransferase (EC 2.1.1.194, Cfr, Cfr methyltransferase, Cfr rRNA methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (adenine2503-C2,C8)-dimethyltransferase. This enzyme catalyses the following chemical reaction

TRNA (cytidine32/uridine32-2'-O)-methyltransferase (EC 2.1.1.200, YfhQ, tRNA:Cm32/Um32 methyltransferase, TrMet(Xm32), TrmJ) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (cytidine32/uridine32-2'-O)-methyltransferase. This enzyme catalyses the following chemical reaction

Multisite-specific tRNA:(cytosine-C5)-methyltransferase is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (cytosine-C5)-methyltransferase. This enzyme catalyses the following chemical reaction

TRNA (cytosine34-C5)-methyltransferase is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (cytosine34-C5)-methyltransferase. This enzyme catalyses the following chemical reaction

TRNA (cytidine32/guanosine34-2'-O)-methyltransferase is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (cytidine32/guanosine34-2'-O)-methyltransferase. This enzyme catalyses the following chemical reaction

tRNA (cytidine56-2'-O)-methyltransferase is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (cytidine56-2'-O)-methyltransferase. This enzyme catalyses the following chemical reaction

TRNA (guanine10-N2)-dimethyltransferase (EC 2.1.1.213, PAB1283, N(2),N(2)-dimethylguanosine tRNA methyltransferase, Trm-G10, PabTrm-G10, PabTrm-m2 2G10 enzyme) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (guanine10-N2)-dimethyltransferase. This enzyme catalyses the following chemical reaction

TRNA (guanine10-N2)-methyltransferase (EC 2.1.1.214, (m2G10) methyltransferase, Trm11-Trm112 complex) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (guanine10-N2)-methyltransferase. This enzyme catalyses the following chemical reaction

TRNA (guanine26-N2/guanine27-N2)-dimethyltransferase (EC 2.1.1.215, Trm1, tRNA (N2,N2-guanine)-dimethyltransferase, tRNA (m2(2G26) methyltransferase, Trm1[tRNA (m2(2)G26) methyltransferase]) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase. This enzyme catalyses the following chemical reaction

TRNA (adenine22-N1)-methyltransferase (EC 2.1.1.217, TrmK, YqfN, Sp1610 (gene), tRNA: m1A22 methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (adenine22-N1)-methyltransferase. This enzyme catalyses the following chemical reaction

TRNA (adenine9-N1)-methyltransferase (EC 2.1.1.218, Trm10p, tRNA(m1G9/m1A9)-methyltransferase, tRNA(m1G9/m1A9)MTase, TK0422p (gene), tRNA m1A9-methyltransferase, tRNA m1A9 Mtase) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (adenine9-N1)-methyltransferase. This enzyme catalyses the following chemical reaction

TRNA (adenine57-N1/adenine58-N1)-methyltransferase (EC 2.1.1.219, TrmI, PabTrmI, AqTrmI, MtTrmI) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (adenine57/adenine58-N1)-methyltransferase. This enzyme catalyses the following chemical reaction:

TRNA (adenine58-N1)-methyltransferase (EC 2.1.1.220, tRNA m1A58 methyltransferase, tRNA (m1A58) methyltransferase, TrmI, tRNA (m1A58) Mtase, Rv2118cp, Gcd10p-Gcd14p, Trm61p-Trm6p) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (adenine58-N1)-methyltransferase. This enzyme catalyses the following chemical reaction

TRNA (guanine9-N1)-methyltransferase (EC 2.1.1.221, Trm10p, tRNA(m1G9/m1A9)-methyltransferase, tRNA(m1G9/m1A9)MTase, tRNA (guanine-N(1)-)-methyltransferase, tRNA m1G9-methyltransferase, tRNA m1G9 MTase) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (guanine9-N1)-methyltransferase. This enzyme catalyses the following chemical reaction

TRNA (guanine6-N2)-methyltransferase (EC 2.1.1.256, methyltransferase Trm14, m2G6 methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (guanine6-N2)-methyltransferase. This enzyme catalyses the following chemical reaction

TRNA (pseudouridine54-N1)-methyltransferase (EC 2.1.1.257, TrmY, m1Psi methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (pseudouridine54-N1)-methyltransferase. This enzyme catalyses the following chemical reaction

References

  1. ↑ Constantinesco F, Motorin Y, Grosjean H (August 1999). "Characterisation and enzymatic properties of tRNA(guanine 26, N (2), N (2))-dimethyltransferase (Trm1p) from Pyrococcus furiosus". Journal of Molecular Biology. 291 (2): 375–92. doi:10.1006/jmbi.1999.2976. PMID   10438627.
  2. ↑ Constantinesco F, Benachenhou N, Motorin Y, Grosjean H (August 1998). "The tRNA(guanine-26,N2-N2) methyltransferase (Trm1) from the hyperthermophilic archaeon Pyrococcus furiosus: cloning, sequencing of the gene and its expression in Escherichia coli". Nucleic Acids Research. 26 (16): 3753–61. doi:10.1093/nar/26.16.3753. PMC   147764 . PMID   9685492.
  3. ↑ Liu J, Liu J, Stråby KB (November 1998). "Point and deletion mutations eliminate one or both methyl group transfers catalysed by the yeast TRM1 encoded tRNA (m22G26)dimethyltransferase". Nucleic Acids Research. 26 (22): 5102–8. doi:10.1093/nar/26.22.5102. PMC   147968 . PMID   9801306.
  4. ↑ Liu J, Zhou GQ, Stråby KB (January 1999). "Caenorhabditis elegans ZC376.5 encodes a tRNA (m2/2G(26))dimethyltransferance in which (246)arginine is important for the enzyme activity". Gene. 226 (1): 73–81. doi:10.1016/s0378-1119(98)00550-2. PMID   10048958.
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