Taxus chinensis

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Taxus chinensis
Taxus chinensis.jpg
Morton Arboretum Acc. 1378-56-2
CITES Appendix II (CITES) [2]
Scientific classification OOjs UI icon edit-ltr.svg
Kingdom: Plantae
Clade: Tracheophytes
Clade: Gymnospermae
Division: Pinophyta
Class: Pinopsida
Order: Cupressales
Family: Taxaceae
Genus: Taxus
Species:
T. chinensis
Binomial name
Taxus chinensis
Subspecies

Taxus chinensis var. mairei

Taxus chinensis is a species of yew. It is commonly called the Chinese yew , though this term also refers to Taxus celebica or Taxus sumatrana .

This plant is used to produce medicines for cancer treatment, [3] [4] including Paclitaxel [5] and Taxifolin (found in Taxus chinensis var. mairei). [6] It can also be used in many other ways and is protected in various ways under Chinese and international law. [4] [7] This protection is in place due to the species' importance to cancer treatment, and its susceptibility to anthropomorphic disturbance. Currently, the species is suffering the consequences of its economic and scientific exploitation for the production of the aforementioned anticancer drugs. [8] [9]

Related Research Articles

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Paclitaxel, sold under the brand name Taxol among others, is a chemotherapy medication used to treat ovarian cancer, esophageal cancer, breast cancer, lung cancer, Kaposi's sarcoma, cervical cancer, and pancreatic cancer. It is administered by intravenous injection. There is also an albumin-bound formulation.

<i>Taxus</i> Genus of conifers in the yew family Taxaceae

Taxus is a genus of coniferous trees or shrubs known as yews in the family Taxaceae. Yews occur around the globe in temperate zones of the northern hemisphere, northernmost in Norway and southernmost in the South Celebes. Some populations exist in tropical highlands.

<span class="mw-page-title-main">Taxaceae</span> Family of conifers

Taxaceae, commonly called the yew family, is a coniferous family which includes six extant and two extinct genera, and about 30 species of plants, or in older interpretations three genera and 7 to 12 species.

<i>Alpinia zerumbet</i> Species of flowering plant

Alpinia zerumbet, commonly known as shell ginger among other names, is a perennial species of ginger native to East Asia. The plants can grow up to 2.5 to 3 meters tall and bear colorful funnel-shaped flowers. They are grown as ornamentals and their leaves are used in cuisine and traditional medicine.

<i>Taxus brevifolia</i> Species of conifer

Taxus brevifolia, the Pacific yew or western yew, is a species of tree in the yew family Taxaceae native to the Pacific Northwest of North America. It is a small evergreen conifer, thriving in moisture and otherwise tending to take the form of a shrub.

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<span class="mw-page-title-main">Taxane</span> Chemical compound

Taxanes are a class of diterpenes. They were originally identified from plants of the genus Taxus (yews), and feature a taxadiene core. Paclitaxel (Taxol) and docetaxel (Taxotere) are widely used as chemotherapy agents. Cabazitaxel was FDA approved to treat hormone-refractory prostate cancer.

<i>Taxus canadensis</i> Species of plant

Taxus canadensis, the Canada yew or Canadian yew, is a conifer native to central and eastern North America, thriving in swampy woods, ravines, riverbanks and on lake shores. Locally called simply "yew", this species is also referred to as American yew or ground-hemlock.

<span class="mw-page-title-main">Paclitaxel total synthesis</span> Ongoing research into paclitaxel synthesis

Paclitaxel total synthesis in organic chemistry is a major ongoing research effort in the total synthesis of paclitaxel (Taxol). This diterpenoid is an important drug in the treatment of cancer but, also expensive because the compound is harvested from a scarce resource, namely the Pacific yew. Not only is the synthetic reproduction of the compound itself of great commercial and scientific importance, but it also opens the way to paclitaxel derivatives not found in nature but with greater potential.

<i>Taxus wallichiana</i> Species of conifer

Taxus wallichiana, the Himalayan yew, is a species of yew, native to the Himalaya and parts of south-east Asia. The species has a variety of uses in traditional medicine. It is currently classified as endangered by the IUCN.

<i>Taxus floridana</i> Species of conifer

Taxus floridana, the Florida yew, is a species of yew, endemic to a small area of under 10 km² on the eastern side of the Apalachicola River in mesophytic forests of northern Florida at altitudes of 15–40 m. It is listed as critically endangered. It is protected in reserves at the Torreya State Park and at the Nature Conservancy's Apalachicola Bluffs and Ravines Preserve, and has legal protection under the United States and Florida Endangered Species laws.

<i>Taxus globosa</i> Species of conifer

Taxus globosa, the Mexican yew, is an evergreen shrub and one of the eight species of yew. The Mexican yew is a rare species, only known to be found in a small number of locations in eastern Mexico, Guatemala, El Salvador and Honduras, and is listed as an endangered species. The Mexican yew is a shrub that grows to an average height of 4.6m. It has large, sharp light green needles growing in ranks on either side of its branches.

<span class="mw-page-title-main">Taxifolin</span> Chemical compound

Taxifolin (5,7,3',4'-flavan-on-ol), also known as dihydroquercetin, belongs to the subclass flavanonols in the flavonoids, which in turn is a class of polyphenols. It is extracted from plants such as Siberian larch and milk thistle.

Bidoup Nui Ba National Park is a national park in districts of Đam Rông and Lạc Dương, in the province of Lâm Đồng, Vietnam.

<span class="mw-page-title-main">Yunnanxane</span> Chemical compound

Yunnanxane is a bioactive taxane diterpenoid first isolated from Taxus wallichiana. Yunnanxane was later isolated from cell cultures of Taxus cuspidata and Taxus chinensis. Four homologous esters of yunnanxane have also been isolated from Taxus. Yunnanxane is reported to have anticancer activity in vitro.

Nông Thị Xuân (1932–1957) was a mistress of Viet Minh leader Ho Chi Minh, who mothered a child with Hồ and died in a vehicle accident shortly after Xuân was an ethnic Nùng from Cao Bằng Province.

Trichoderma theobromicola is a species of endophytic fungus in the family Hypocreaceae. It was first isolated from the trunk of a healthy cacao tree in Amazonian Peru. It produces a volatile antibiotic that inhibits development of M. roreri.

Trichoderma paucisporum is a species of endophytic fungus in the family Hypocreaceae. It was first isolated in Ecuador from cacao pods infected with frosty pod rot, Moniliophthora roreri. It produces a volatile antibiotic that inhibits development of M. roreri.

<i>Taxus mairei</i> Species of plant in the family Taxaceae

Taxus mairei, Maire's yew, is a species of conifer in the yew family Taxaceae, native to Nepal, Assam, central and southern China, Hainan, Taiwan and Vietnam. It is extensively harvested for its paclitaxel (taxol) content in China.

<span class="mw-page-title-main">8th Central Committee of the Communist Party of Vietnam</span> Central Committee of the Communist Party of Vietnam

The 8th Central Committee of the Communist Party of Vietnam (CPV) was elected at the 8th CPV National Congress. It elected the 8th Politburo and the 8th Secretariat.

References

  1. Thomas, P.; Li, N.; Christian, T. (2013). "Taxus chinensis". IUCN Red List of Threatened Species . 2013: e.T42548A2987120. doi: 10.2305/IUCN.UK.2013-1.RLTS.T42548A2987120.en . Retrieved 11 November 2021.
  2. "Appendices | CITES". cites.org. Retrieved 2024-01-17.
  3. "藥用植物圖像數據庫 - 紅豆杉 Hongdoushan". 藥用植物圖像數據庫.
  4. 1 2 "Taxus chinensis (Chinese Yew)". North Carolina Extension Gardener Plant Toolbox. North Carolina State University. Retrieved 2022-07-20.
  5. Pyo, Sang-Hyun; Park, Heung-Bok; Song, Bong-Kyu; Han, Byung-Hee; Kim, Jin-Hyun (2004). "A large-scale purification of paclitaxel from cell cultures of Taxus chinensis". Process Biochemistry. 39 (12): 1985–1991. doi:10.1016/j.procbio.2003.09.028.
  6. Li, Cunfang; Huo, Changhong; Zhang, Manli; Shi, Qingwen (2008). "Chemistry of Chinese yew, Taxus chinensis var. mairei". Biochemical Systematics and Ecology. 36 (4): 266–282. Bibcode:2008BioSE..36..266L. doi:10.1016/j.bse.2007.08.002.
  7. Zhang, Jin-Tun; Ru, Wenming (2010). "Population characteristics of endangered species Taxus chinensis var. mairei and its conservation strategy in Shanxi, China". Population Ecology. 52 (3): 407–416. Bibcode:2010PopEc..52..407Z. doi:10.1007/s10144-009-0192-y. ISSN   1438-3896. S2CID   24740840.
  8. Vu, Dinh Duy; Bui, Thi Tuyet Xuan; Nguyen, Minh Tam; Vu, Dinh Giap; Nguyen, Minh Duc; Bui, Van Thang; Huang, Xiaohua; Zhang, Yi (2017-03-01). "Genetic diversity in two threatened species in Vietnam: Taxus chinensis and Taxus wallichiana". Journal of Forestry Research. 28 (2): 265–272. doi:10.1007/s11676-016-0323-1. ISSN   1993-0607. S2CID   255350116.
  9. Liao, Weifang; Zhao, Shengying; Zhang, Meng; Dong, Kaige; Chen, Ying; Fu, Chunhua; Yu, Longjiang (2017). "Transcriptome Assembly and Systematic Identification of Novel Cytochrome P450s in Taxus chinensis". Frontiers in Plant Science. 8: 1468. doi: 10.3389/fpls.2017.01468 . ISSN   1664-462X. PMC   5572210 . PMID   28878800.