Tetrahydrocolumbamine 2-O-methyltransferase

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tetrahydrocolumbamine 2-O-methyltransferase
Identifiers
EC no. 2.1.1.89
CAS no. 93792-09-7
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In enzymology, a tetrahydrocolumbamine 2-O-methyltransferase (EC 2.1.1.89) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + 5,8,13,13a-tetrahydrocolumbamine S-adenosyl-L-homocysteine + tetrahydropalmatine

Thus, the two substrates of this enzyme are S-adenosyl methionine and 5,8,13,13a-tetrahydrocolumbamine, whereas its two products are S-adenosylhomocysteine and tetrahydropalmatine.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:5,8,13,13a-tetrahydrocolumbamine 2-O-methyltransferase. This enzyme is also called tetrahydrocolumbamine methyltransferase. This enzyme participates in alkaloid biosynthesis i.

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References


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