Unsaturated rhamnogalacturonyl hydrolase

Unsaturated rhamnogalacturonyl hydrolase
Identifiers
EC no.	3.2.1.172
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Unsaturated rhamnogalacturonyl hydrolase (EC 3.2.1.172, YteR, YesR) is an enzyme with systematic name 2-O-(4-deoxy-beta-L-threo-hex-4-enopyranuronosyl)-alpha-L-rhamnopyranose hydrolase. ^{[1] [2] [3]} This enzyme catalyses the following chemical reaction

2-O-(4-deoxy-beta-L-threo-hex-4-enopyranuronosyl)-alpha-L-rhamnopyranose + H₂O ${\displaystyle \rightleftharpoons }$ 5-dehydro-4-deoxy-D-glucuronate + L-rhamnopyranose

The enzyme is part of the degradation system for rhamnogalacturonan I in Bacillus subtilis strain 168.

References

1. Itoh T, Ochiai A, Mikami B, Hashimoto W, Murata K (July 2006). "A novel glycoside hydrolase family 105: the structure of family 105 unsaturated rhamnogalacturonyl hydrolase complexed with a disaccharide in comparison with family 88 enzyme complexed with the disaccharide". Journal of Molecular Biology. 360 (3): 573–85. doi:10.1016/j.jmb.2006.04.047. PMID   16781735.
2. Zhang R, Minh T, Lezondra L, Korolev S, Moy SF, Collart F, Joachimiak A (August 2005). "1.6 A crystal structure of YteR protein from Bacillus subtilis, a predicted lyase". Proteins. 60 (3): 561–5. doi:10.1002/prot.20410. PMC   2792013 . PMID   15906318.
3. Itoh T, Ochiai A, Mikami B, Hashimoto W, Murata K (September 2006). "Structure of unsaturated rhamnogalacturonyl hydrolase complexed with substrate". Biochemical and Biophysical Research Communications. 347 (4): 1021–9. Bibcode:2006BBRC..347.1021I. doi:10.1016/j.bbrc.2006.07.034. PMID   16870154.

External links

• Unsaturated+rhamnogalacturonyl+hydrolase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)